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Adam Nelson
Adam Nelson
Professor of Chemical Biology, University of Leeds
Verified email at leeds.ac.uk - Homepage
Title
Cited by
Cited by
Year
Synthesis of natural‐product‐like molecules with over eighty distinct scaffolds
D Morton, S Leach, C Cordier, S Warriner, A Nelson
Angewandte Chemie International Edition 48 (1), 104-109, 2009
2622009
Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries
C Cordier, D Morton, S Murrison, A Nelson, C O'Leary-Steele
Natural product reports 25 (4), 719-737, 2008
2482008
Recent advances and applications of iridium-catalysed asymmetric allylic substitution
P Tosatti, A Nelson, SP Marsden
Organic & biomolecular chemistry 10 (16), 3147-3163, 2012
2182012
Asymmetric Phase‐Transfer Catalysis
A Nelson
Angewandte Chemie International Edition 38 (11), 1583-1585, 1999
2091999
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase
AN Bullock, JÉ Debreczeni, OY Fedorov, A Nelson, BD Marsden, S Knapp
Journal of medicinal chemistry 48 (24), 7604-7614, 2005
2032005
Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells
MP Storm, HK Bone, CG Beck, PY Bourillot, V Schreiber, T Damiano, ...
Journal of Biological Chemistry 282 (9), 6265-6273, 2007
1862007
Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution
GJ Williams, S Domann, A Nelson, A Berry
Proceedings of the National Academy of Sciences 100 (6), 3143-3148, 2003
1482003
Convergent, Regiospecific Synthesis of Quinolines from o-Aminophenylboronates
J Horn, SP Marsden, A Nelson, D House, GG Weingarten
Organic letters 10 (18), 4117-4120, 2008
1432008
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3
HK Bone, AS Nelson, CE Goldring, D Tosh, MJ Welham
Journal of cell science, jcs. 081679, 2011
1372011
Engineering aldolases as biocatalysts
CL Windle, M Müller, A Nelson, A Berry
Current opinion in chemical biology 19, 25-33, 2014
1142014
Directed evolution of enzymes for biocatalysis and the life sciences
GJ Williams, AS Nelson, A Berry
Cellular and Molecular Life Sciences CMLS 61 (24), 3034-3046, 2004
1102004
A divergent synthetic approach to diverse molecular scaffolds: assessment of lead-likeness using LLAMA, an open-access computational tool
I Colomer, CJ Empson, P Craven, Z Owen, RG Doveston, I Churcher, ...
Chemical Communications 52 (45), 7209-7212, 2016
1082016
Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective
A Karawajczyk, F Giordanetto, J Benningshof, D Hamza, T Kalliokoski, ...
Drug Discovery Today 20 (11), 1310-1316, 2015
1062015
Towards phase-transfer catalysts with a chiral anion: inducing asymmetry in the reactions of cations
C Carter, S Fletcher, A Nelson
Tetrahedron: Asymmetry 14 (14), 1995-2004, 2003
1022003
Directed evolution of aldolases for exploitation in synthetic organic chemistry
A Bolt, A Berry, A Nelson
Archives of biochemistry and biophysics 474 (2), 318-330, 2008
962008
Predicting and Experimentally Validating Hot-Spot Residues at Protein–Protein Interfaces
AA Ibarra, GJ Bartlett, Z Hegedüs, S Dutt, F Hobor, KA Horner, ...
ACS chemical biology 14 (10), 2252-2263, 2019
842019
A unified lead-oriented synthesis of over fifty molecular scaffolds
RG Doveston, P Tosatti, M Dow, DJ Foley, HY Li, AJ Campbell, D House, ...
Organic & biomolecular chemistry 13 (3), 859-865, 2015
802015
Creation of a pair of stereochemically complementary biocatalysts
GJ Williams, T Woodhall, LM Farnsworth, A Nelson, A Berry
Journal of the American Chemical Society 128 (50), 16238-16247, 2006
802006
High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers
HL Martin, M Adams, J Higgins, J Bond, EE Morrison, SM Bell, S Warriner, ...
PloS one 9 (2), e88338, 2014
782014
Evaluating new chemistry to drive molecular discovery: fit for purpose?
DJ Foley, A Nelson, SP Marsden
Angewandte Chemie International Edition 55 (44), 13650-13657, 2016
772016
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