Lasse Ebdrup Pedersen
Lasse Ebdrup Pedersen
NNF Center for Biosustainability at The Technical University of Denmark
Verified email at biosustain.DTU.dk - Homepage
Title
Cited by
Cited by
Year
Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae
T Jakočiūnas, I Bonde, M Herrgård, SJ Harrison, M Kristensen, ...
Metabolic engineering 28, 213-222, 2015
2782015
Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway
JS Lee, TB Kallehauge, LE Pedersen, HF Kildegaard
Scientific reports 5, 8572, 2015
1402015
Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web‐based target finding tool
C Ronda, LE Pedersen, HG Hansen, TB Kallehauge, MJ Betenbaugh, ...
Biotechnology and bioengineering 111 (8), 1604-1616, 2014
1362014
CRMAGE: CRISPR optimized mage recombineering
C Ronda, LE Pedersen, MOA Sommer, AT Nielsen
Scientific reports 6 (1), 1-11, 2016
1312016
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell Systems 3 (5), 434-443. e8, 2016
1222016
One‐step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment
LM Grav, JS Lee, S Gerling, TB Kallehauge, AH Hansen, S Kol, GM Lee, ...
Biotechnology journal 10 (9), 1446-1456, 2015
872015
CRISPy-web: An online resource to design sgRNAs for CRISPR applications
K Blin, LE Pedersen, T Weber, SY Lee
Synthetic and Systems Biotechnology 1 (2), 118-121, 2016
602016
Accelerated homology‐directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment
JS Lee, LM Grav, LE Pedersen, GM Lee, HF Kildegaard
Biotechnology and bioengineering 113 (11), 2518-2523, 2016
492016
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
TB Kallehauge, S Li, LE Pedersen, TK Ha, D Ley, MR Andersen, ...
Scientific reports 7 (1), 1-12, 2017
352017
Evolutionary and experimental analyses of inorganic phosphate transporter PiT family reveals two related signature sequences harboring highly conserved aspartic acids critical …
P Bøttger, L Pedersen
The FEBS journal 272 (12), 3060-3074, 2005
322005
CasPER, a method for directed evolution in genomic contexts using mutagenesis and CRISPR/Cas9
T Jakočiūnas, LE Pedersen, AV Lis, MK Jensen, JD Keasling
Metabolic engineering 48, 288-296, 2018
282018
Regulation of cell proliferation and cell density by the inorganic phosphate transporter PiT1
K Byskov, N Jensen, IB Kongsfelt, M Wielsøe, LE Pedersen, C Haldrup, ...
Cell division 7 (1), 7, 2012
272012
Elucidation of the CHO super-ome (CHO-SO) by proteoinformatics
A Kumar, D Baycin-Hizal, D Wolozny, LE Pedersen, NE Lewis, K Heffner, ...
Journal of proteome research 14 (11), 4687-4703, 2015
212015
Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data
AM Lund, CS Kaas, J Brandl, LE Pedersen, HF Kildegaard, C Kristensen, ...
BMC systems biology 11 (1), 37, 2017
122017
High levels of the type III inorganic phosphate transporter PiT1 (SLC20A1) can confer faster cell adhesion
IB Kongsfelt, K Byskov, LE Pedersen, L Pedersen
Experimental cell research 326 (1), 57-67, 2014
92014
Awakening dormant glycosyltransferases in CHO cells with CRISPRa
KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ...
Biotechnology and Bioengineering 117 (2), 593-598, 2020
52020
Multiplex secretome engineering enhances recombinant protein production and purity
S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ...
Nature communications 11 (1), 1-10, 2020
32020
Technical University of Denmark
MJ Herrgard
Denmark, 0
3
Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion
D Ley, S Pereira, LE Pedersen, J Arnsdorf, H Hefzi, AM Davy, TK Ha, ...
Metabolic engineering 56, 120-129, 2019
22019
Adaptive laboratory evolution reveals general and specific chemical tolerance mechanisms and enhances biochemical production
RM Lennen, K Jensen, ET Mohammed, S Malla, RA Börner, K Chekina, ...
BioRxiv, 634105, 2019
22019
The system can't perform the operation now. Try again later.
Articles 1–20