Jan Van den Bossche
Jan Van den Bossche
Principal Investigator, VU University Medical Center Amsterdam
Verified email at - Homepage
Cited by
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Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity
K Movahedi, M Guilliams, J Van den Bossche, R Van den Bergh, ...
Blood, The Journal of the American Society of Hematology 111 (8), 4233-4244, 2008
Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C (high) MonocytesOrigin and Functions of Tumor Macrophage Subsets
K Movahedi, D Laoui, C Gysemans, M Baeten, G Stangé, ...
Cancer research 70 (14), 5728-5739, 2010
Macrophage immunometabolism: where are we (going)?
J Van den Bossche, LA O’Neill, D Menon
Trends in immunology 38 (6), 395-406, 2017
Mitochondrial dysfunction prevents repolarization of inflammatory macrophages
J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ...
Cell reports 17 (3), 684-696, 2016
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans
FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ...
Circulation 134 (8), 611-624, 2016
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
D Laoui, K Movahedi, E Van Overmeire, J Van den Bossche, E Schouppe, ...
International Journal of Developmental Biology 55 (7-8-9), 861-867, 2011
Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis
J Van den Bossche, J Baardman, MPJ de Winther
JoVE (Journal of Visualized Experiments), e53424, 2015
Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs
J Van den Bossche, B Malissen, A Mantovani, P De Baetselier, ...
Blood, The Journal of the American Society of Hematology 119 (7), 1623-1633, 2012
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions
MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ...
EMBO molecular medicine 6 (9), 1124-1132, 2014
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia
SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ...
European heart journal 38 (20), 1584-1593, 2017
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
J Van den Bossche, P Bogaert, J Van Hengel, CJ Guérin, G Berx, ...
Blood, The Journal of the American Society of Hematology 114 (21), 4664-4674, 2009
A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia
J Baardman, SGS Verberk, KHM Prange, M van Weeghel, ...
Cell reports 25 (8), 2044-2052. e5, 2018
Single-cell metabolic profiling of human cytotoxic T cells
FJ Hartmann, D Mrdjen, E McCaffrey, DR Glass, NF Greenwald, ...
Nature biotechnology 39 (2), 186-197, 2021
Metabolic alterations in aging macrophages: ingredients for inflammaging?
AA Van Beek, J Van den Bossche, PG Mastroberardino, MPJ De Winther, ...
Trends in immunology 40 (2), 113-127, 2019
Pivotal Advance: Arginase‐1‐independent polyamine production stimulates the expression of IL‐4‐induced alternatively activated macrophage markers while inhibiting LPS‐induced …
J Van den Bossche, WH Lamers, ES Koehler, JMC Geuns, L Alhonen, ...
Journal of leukocyte biology 91 (5), 685-699, 2012
Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site
D Laoui, E Van Overmeire, K Movahedi, J Van den Bossche, E Schouppe, ...
Immunobiology 216 (11), 1192-1202, 2011
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality
MR Boon, SAA van den Berg, Y Wang, J van den Bossche, ...
PLoS One 8 (9), e74083, 2013
Macrophage polarization: the epigenetic point of view
J Van den Bossche, AE Neele, MA Hoeksema, MPJ De Winther
Current opinion in lipidology 25 (5), 367-373, 2014
Nuclear receptor Nur77 limits the macrophage inflammatory response through transcriptional reprogramming of mitochondrial metabolism
DS Koenis, L Medzikovic, PB van Loenen, M van Weeghel, S Huveneers, ...
Cell reports 24 (8), 2127-2140. e7, 2018
Immunometabolism in the single-cell era
MN Artyomov, J Van den Bossche
Cell metabolism 32 (5), 710-725, 2020
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