| SOX9 is required for maintenance of the pancreatic progenitor cell pool PA Seymour, KK Freude, MN Tran, EE Mayes, J Jensen, R Kist, G Scherer, ... Proceedings of the National Academy of Sciences 104 (6), 1865-1870, 2007 | 695 | 2007 |
| Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors AE Schaffer, KK Freude, SB Nelson, M Sander Developmental cell 18 (6), 1022-1029, 2010 | 336 | 2010 |
| Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation A Ochalek, B Mihalik, HX Avci, A Chandrasekaran, A Téglási, I Bock, ... Alzheimer's research & therapy 9, 1-19, 2017 | 191 | 2017 |
| Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation VM Kalscheuer, K Freude, L Musante, LR Jensen, HG Yntema, J Gécz, ... Nature genetics 35 (4), 313-315, 2003 | 190 | 2003 |
| Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine–binding protein cause nonsyndromic X-linked mental retardation K Freude, K Hoffmann, LR Jensen, MB Delatycki, V Des Portes, B Moser, ... The American Journal of Human Genetics 75 (2), 305-309, 2004 | 172 | 2004 |
| A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation PA Seymour, KK Freude, CL Dubois, HP Shih, NA Patel, M Sander Developmental biology 323 (1), 19-30, 2008 | 152 | 2008 |
| Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells KK Freude, M Penjwini, JL Davis, FM LaFerla, M Blurton-Jones Journal of Biological Chemistry 286 (27), 24264-24274, 2011 | 132 | 2011 |
| A Sox9/Fgf feed-forward loop maintains pancreatic organ identity PA Seymour, HP Shih, NA Patel, KK Freude, R Xie, CJ Lim, M Sander Development 139 (18), 3363-3372, 2012 | 130 | 2012 |
| Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome I Borg, K Freude, S Kübart, K Hoffmann, C Menzel, F Laccone, H Firth, ... European Journal of Human Genetics 13 (8), 921-927, 2005 | 120 | 2005 |
| Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid KC Walls, P Coskun, JL Gallegos-Perez, N Zadourian, K Freude, ... Journal of Biological Chemistry 287 (36), 30317-30327, 2012 | 97 | 2012 |
| Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain N Prakash, E Puelles, K Freude, D Trümbach, D Omodei, M Di Salvio, ... Oxford University Press for The Company of Biologists Limited 136 (15), 2545 …, 2009 | 88 | 2009 |
| Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B Y Zhang, B Schmid, NK Nikolaisen, MA Rasmussen, BI Aldana, M Agger, ... Stem cell reports 8 (3), 648-658, 2017 | 79 | 2017 |
| Implications of glycosylation in Alzheimer’s disease H Haukedal, KK Freude Frontiers in Neuroscience 14, 625348, 2021 | 73 | 2021 |
| Neurosphere based differentiation of human iPSC improves astrocyte differentiation S Zhou, K Szczesna, A Ochalek, J Kobolák, E Varga, C Nemes, ... Stem Cells International 2016, 2016 | 70 | 2016 |
| Glial cells in glaucoma: friends, foes, and potential therapeutic targets MY García-Bermúdez, KK Freude, ZA Mouhammad, P Van Wijngaarden, ... Frontiers in neurology 12, 624983, 2021 | 63 | 2021 |
| Induced pluripotent stem cells throughout the animal kingdom: availability and applications LV de Figueiredo Pessôa, FF Bressan, KK Freude World Journal of Stem Cells 11 (8), 491, 2019 | 57 | 2019 |
| Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges A Poon, Y Zhang, A Chandrasekaran, P Phanthong, B Schmid, ... New biotechnology 39, 190-198, 2017 | 57 | 2017 |
| Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1 C Pires, B Schmid, C Petræus, A Poon, N Nimsanor, TT Nielsen, ... Stem Cell Research 17 (2), 285-288, 2016 | 57 | 2016 |
| Implications of microglia in amyotrophic lateral sclerosis and frontotemporal dementia H Haukedal, K Freude Journal of molecular biology 431 (9), 1818-1829, 2019 | 55 | 2019 |
| Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer’s disease HR Frederiksen, H Haukedal, K Freude BioMed research international 2019, 2019 | 52 | 2019 |
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