| Misfolded CuZnSOD and amyotrophic lateral sclerosis JS Valentine, PJ Hart Proceedings of the National Academy of Sciences 100 (7), 3617-3622, 2003 | 661 | 2003 |
| Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS JS Elam, AB Taylor, R Strange, S Antonyuk, PA Doucette, JA Rodriguez, ... Nature Structural & Molecular Biology 10 (6), 461-467, 2003 | 399 | 2003 |
| Crystal structure of the human TβR2 ectodomain–TGF-β3 complex PJ Hart, S Deep, AB Taylor, Z Shu, CS Hinck, AP Hinck Nature structural biology 9 (3), 203-208, 2002 | 368 | 2002 |
| Sequence-specific recognition and cooperative dimerization of N-terminal aromatic peptides in aqueous solution by a synthetic host LM Heitmann, AB Taylor, PJ Hart, AR Urbach Journal of the American Chemical Society 128 (38), 12574-12581, 2006 | 330 | 2006 |
| Molecular recognition of insulin by a synthetic receptor JM Chinai, AB Taylor, LM Ryno, ND Hargreaves, CA Morris, PJ Hart, ... Journal of the American Chemical Society 133 (23), 8810-8813, 2011 | 326 | 2011 |
| A Structure-Based Mechanism for Copper−Zinc Superoxide Dismutase, PJ Hart, MM Balbirnie, NL Ogihara, AM Nersissian, MS Weiss, ... Biochemistry 38 (7), 2167-2178, 1999 | 320 | 1999 |
| The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis RW Strange, S Antonyuk, MA Hough, PA Doucette, JA Rodriguez, PJ Hart, ... Journal of molecular biology 328 (4), 877-891, 2003 | 305 | 2003 |
| Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease M Prudencio, PJ Hart, DR Borchelt, PM Andersen Human molecular genetics 18 (17), 3217-3226, 2009 | 292 | 2009 |
| Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants MA Hough, JG Grossmann, SV Antonyuk, RW Strange, PA Doucette, ... Proceedings of the National Academy of Sciences 101 (16), 5976-5981, 2004 | 275 | 2004 |
| Structure of the Hsp110: Hsc70 nucleotide exchange machine JP Schuermann, J Jiang, J Cuellar, O Llorca, L Wang, LE Gimenez, S Jin, ... Molecular cell 31 (2), 232-243, 2008 | 266 | 2008 |
| Shall we dance? How a multicopper oxidase chooses its electron transfer partner L Quintanar, C Stoj, AB Taylor, PJ Hart, DJ Kosman, EI Solomon Accounts of chemical research 40 (6), 445-452, 2007 | 250 | 2007 |
| The crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1-Å resolution Y Liu, PJ Hart, MP Schlunegger, D Eisenberg Proceedings of the National Academy of Sciences 95 (7), 3437-3442, 1998 | 238 | 1998 |
| Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS CM Karch, M Prudencio, DD Winkler, PJ Hart, DR Borchelt Proceedings of the National Academy of Sciences 106 (19), 7774-7779, 2009 | 228 | 2009 |
| The copper-iron connection in biology: structure of the metallo-oxidase Fet3p AB Taylor, CS Stoj, L Ziegler, DJ Kosman, PJ Hart Proceedings of the National Academy of Sciences 102 (43), 15459-15464, 2005 | 224 | 2005 |
| A missing link in cupredoxins: Crystal structure of cucumber stellacyanin at 1.6 Å resolution PJ Hart, D Eisenberg, AM Nersissian, JS Valentine, RG Herrmann, ... Protein science 5 (11), 2175-2183, 1996 | 224 | 1996 |
| The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 Å resolution PJ Hart, HD Pfluger, AF Monzingo, T Hollis, JD Robertus J. Mol. Biol 248, 402-413, 1995 | 213 | 1995 |
| Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant: Insights into the molecular basis for dimer stability PA Doucette, LJ Whitson, X Cao, V Schirf, B Demeler, JS Valentine, ... Journal of Biological Chemistry 279 (52), 54558-54566, 2004 | 212 | 2004 |
| Uclacyanins, stellacyanins, and plantacyanins are distinct subfamilies of phytocyanins: Plant‐specific mononuclear blue copper proteins AM Nersissian, JS Valentine, C Immoos, MG Hill, PJ Hart, G Williams, ... Protein Science 7 (9), 1915-1929, 1998 | 200 | 1998 |
| Chitinases, chitosanases, and lysozymes can be divided into procaryotic and eucaryotic families sharing a conserved core AF Monzingo, EM Marcotte, PJ Hart, JD Robertas nature structural biology 3 (2), 133-140, 1996 | 194 | 1996 |
| Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites CLL Valentim, D Cioli, FD Chevalier, X Cao, AB Taylor, SP Holloway, ... Science 342 (6164), 1385-1389, 2013 | 168 | 2013 |
Brad S. RothbergProfessor of Medical Genetics & Molecular Biochemistry, Temple University School of MedicineVerified email at temple.edu
