Mass cytometry: single cells, many features MH Spitzer, GP Nolan Cell 165 (4), 780-791, 2016 | 1194 | 2016 |
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites D Dodd, MH Spitzer, W Van Treuren, BD Merrill, AJ Hryckowian, ... Nature 551 (7682), 648-652, 2017 | 979 | 2017 |
Systemic immunity in cancer KJ Hiam-Galvez, BM Allen, MH Spitzer Nature reviews cancer 21 (6), 345-359, 2021 | 871 | 2021 |
Systemic immunity is required for effective cancer immunotherapy MH Spitzer, Y Carmi, NE Reticker-Flynn, SS Kwek, D Madhireddy, ... Cell 168 (3), 487-502. e15, 2017 | 863 | 2017 |
Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm ER Zunder, R Finck, GK Behbehani, ED Amir, S Krishnaswamy, ... Nature protocols 10 (2), 316-333, 2015 | 527 | 2015 |
Intratumoral CD4+ T cells mediate anti-tumor cytotoxicity in human bladder cancer DY Oh, SS Kwek, SS Raju, T Li, E McCarthy, E Chow, D Aran, A Ilano, ... Cell 181 (7), 1612-1625. e13, 2020 | 523 | 2020 |
Automated mapping of phenotype space with single-cell data N Samusik, Z Good, MH Spitzer, KL Davis, GP Nolan Nature methods 13 (6), 493-496, 2016 | 387 | 2016 |
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states D Furman, J Chang, L Lartigue, CR Bolen, F Haddad, B Gaudilliere, ... Nature medicine 23 (2), 174-184, 2017 | 380 | 2017 |
The transcriptional landscape of αβ T cell differentiation M Mingueneau, T Kreslavsky, D Gray, T Heng, R Cruse, J Ericson, ... Nature immunology 14 (6), 619-632, 2013 | 300 | 2013 |
Engineered tumor-targeted T cells mediate enhanced anti-tumor efficacy both directly and through activation of the endogenous immune system MP Avanzi, O Yeku, X Li, DP Wijewarnasuriya, DG van Leeuwen, ... Cell reports 23 (7), 2130-2141, 2018 | 285 | 2018 |
An interactive reference framework for modeling a dynamic immune system MH Spitzer, PF Gherardini, GK Fragiadakis, N Bhattacharya, RT Yuan, ... Science 349 (6244), 1259425, 2015 | 263 | 2015 |
Systemic dysfunction and plasticity of the immune macroenvironment in cancer models BM Allen, KJ Hiam, CE Burnett, A Venida, R DeBarge, I Tenvooren, ... Nature medicine 26 (7), 1125-1134, 2020 | 262 | 2020 |
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity Y Carmi, MH Spitzer, IL Linde, BM Burt, TR Prestwood, N Perlman, ... Nature 521 (7550), 99-104, 2015 | 247 | 2015 |
Conditional density-based analysis of T cell signaling in single-cell data S Krishnaswamy, MH Spitzer, M Mingueneau, SC Bendall, O Litvin, ... Science 346 (6213), 1250689, 2014 | 244 | 2014 |
Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry G Han, MH Spitzer, SC Bendall, WJ Fantl, GP Nolan Nature protocols 13 (10), 2121-2148, 2018 | 205 | 2018 |
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19 MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ... Science translational medicine 13 (612), eabh2624, 2021 | 183 | 2021 |
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis NE Reticker-Flynn, W Zhang, JA Belk, PA Basto, NK Escalante, ... Cell 185 (11), 1924-1942. e23, 2022 | 168 | 2022 |
Depletion of microbiome-derived molecules in the host using Clostridium genetics CJ Guo, BM Allen, KJ Hiam, D Dodd, W Van Treuren, S Higginbottom, ... Science 366 (6471), eaav1282, 2019 | 134 | 2019 |
Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes MK Rahim, TLH Okholm, KB Jones, EE McCarthy, CC Liu, JL Yee, ... Cell 186 (6), 1127-1143. e18, 2023 | 124 | 2023 |
The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes S Dong, KJ Hiam-Galvez, CT Mowery, KC Herold, SE Gitelman, ... JCI insight 6 (18), 2021 | 124 | 2021 |