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Matthew H Spitzer
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Mass cytometry: single cells, many features
MH Spitzer, GP Nolan
Cell 165 (4), 780-791, 2016
9172016
Systemic immunity is required for effective cancer immunotherapy
MH Spitzer, Y Carmi, NE Reticker-Flynn, SS Kwek, D Madhireddy, ...
Cell 168 (3), 487-502. e15, 2017
6792017
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites
D Dodd, MH Spitzer, W Van Treuren, BD Merrill, AJ Hryckowian, ...
Nature 551 (7682), 648-652, 2017
6542017
Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm
ER Zunder, R Finck, GK Behbehani, ED Amir, S Krishnaswamy, ...
Nature protocols 10 (2), 316-333, 2015
4232015
Systemic immunity in cancer
KJ Hiam-Galvez, BM Allen, MH Spitzer
Nature reviews cancer 21 (6), 345-359, 2021
3522021
Intratumoral CD4+ T cells mediate anti-tumor cytotoxicity in human bladder cancer
DY Oh, SS Kwek, SS Raju, T Li, E McCarthy, E Chow, D Aran, A Ilano, ...
Cell 181 (7), 1612-1625. e13, 2020
3062020
Automated mapping of phenotype space with single-cell data
N Samusik, Z Good, MH Spitzer, KL Davis, GP Nolan
Nature methods 13 (6), 493-496, 2016
2992016
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states
D Furman, J Chang, L Lartigue, CR Bolen, F Haddad, B Gaudilliere, ...
Nature medicine 23 (2), 174-184, 2017
2812017
The transcriptional landscape of αβ T cell differentiation
M Mingueneau, T Kreslavsky, D Gray, T Heng, R Cruse, J Ericson, ...
Nature immunology 14 (6), 619-632, 2013
2612013
An interactive reference framework for modeling a dynamic immune system
MH Spitzer, PF Gherardini, GK Fragiadakis, N Bhattacharya, RT Yuan, ...
Science 349 (6244), 1259425, 2015
2292015
Conditional density-based analysis of T cell signaling in single-cell data
S Krishnaswamy, MH Spitzer, M Mingueneau, SC Bendall, O Litvin, ...
Science 346 (6213), 1250689, 2014
2202014
Engineered tumor-targeted T cells mediate enhanced anti-tumor efficacy both directly and through activation of the endogenous immune system
MP Avanzi, O Yeku, X Li, DP Wijewarnasuriya, DG van Leeuwen, ...
Cell reports 23 (7), 2130-2141, 2018
2152018
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity
Y Carmi, MH Spitzer, IL Linde, BM Burt, TR Prestwood, N Perlman, ...
Nature 521 (7550), 99-104, 2015
1972015
Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry
G Han, MH Spitzer, SC Bendall, WJ Fantl, GP Nolan
Nature protocols 13 (10), 2121-2148, 2018
1472018
Systemic dysfunction and plasticity of the immune macroenvironment in cancer models
BM Allen, KJ Hiam, CE Burnett, A Venida, R DeBarge, I Tenvooren, ...
Nature medicine 26 (7), 1125-1134, 2020
1452020
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ...
Science translational medicine 13 (612), eabh2624, 2021
1002021
Depletion of microbiome-derived molecules in the host using Clostridium genetics
CJ Guo, BM Allen, KJ Hiam, D Dodd, W Van Treuren, S Higginbottom, ...
Science 366 (6471), eaav1282, 2019
792019
Comprehensive immune monitoring of clinical trials to advance human immunotherapy
FJ Hartmann, J Babdor, PF Gherardini, EAD Amir, K Jones, B Sahaf, ...
Cell reports 28 (3), 819-831. e4, 2019
762019
Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice
M Mingueneau, S Krishnaswamy, MH Spitzer, SC Bendall, EL Stone, ...
Proceedings of the National Academy of Sciences 111 (46), 16466-16471, 2014
632014
Jak1 integrates cytokine sensing to regulate hematopoietic stem cell function and stress hematopoiesis
M Kleppe, MH Spitzer, S Li, CE Hill, L Dong, E Papalexi, S De Groote, ...
Cell stem cell 21 (4), 489-501. e7, 2017
622017
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Articles 1–20