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Matthew Dearman
Matthew Dearman
RIA iMED Bioscience
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile
L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ...
Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018
662018
Efficacious inhaled PDE4 inhibitors with low emetic potential and long duration of action for the treatment of COPD
C De Savi, RJ Cox, DJ Warner, AR Cook, MR Dickinson, A McDonough, ...
Journal of Medicinal Chemistry 57 (11), 4661-4676, 2014
322014
Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators
M Hemmerling, K Edman, M Lepistö, A Eriksson, S Ivanova, J Dahmén, ...
Bioorganic & Medicinal Chemistry Letters 26 (23), 5741-5748, 2016
202016
Effects of a selective glucocorticoid receptor modulator (AZD9567) versus prednisolone in healthy volunteers: two phase 1, single-blind, randomised controlled trials
TH Myrbäck, S Prothon, K Edman, J Leander, M Hashemi, M Dearman, ...
The Lancet Rheumatology 2 (1), e31-e41, 2020
162020
SAT0245 Azd9567: a novel oral selective glucocorticoid receptor modulator, demonstrated to have an improved therapeutic ratio compared to prednisolone in pre-clinical studies …
R Hendrickx, T Hegelund-Myrbäck, M Dearman, S Prothon, G Edenro, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 984-985, 2018
22018
Identification of AZD9567, an anti-inflammatory glucocorticoid receptor modulator with improved side effect profile
L Ripa, M Dearman, G Edenro, K Edman, R Hendrickx, M Lepisto, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
12017
Inhaled bacterial mimetic increases PAD4-dependent NETosis in the lungs
T Andreasson, L Odqvist, S Arlbrandt, C Wingren, P Berntsson, M Rhedin, ...
European Respiratory Journal 56 (suppl 64), 2020
2020
SAT0251 Selective glucocorticoid receptor modulator shows potent anti-inflammatory effect with improved metabolic profile in a phase i study supported by in vitro data
TH Myrbäck, S Prothon, M Dearman, G Edenro, J Leander, M Hashemi, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 987-987, 2018
2018
Next generation glucocorticoid receptor modulators
K Edman, G Belfield, M Dearman, G Edenro, S Geschwindner, ...
Endocrine Abstracts 54, 2018
2018
Biphasic Granulocytic Inflammation And Bronchoconstriction Towards Serotonin Occurs Detached From Parenchymal Hyperresponsiveness In A Rat Model Of Allergic Asthma
B Fuchs, MS Dearman, M Fredberg, A Smailagic, L Swedin
B33. GRANULOCYTE ACTIVATION IN LUNG DISEASE, A2757-A2757, 2014
2014
B33 GRANULOCYTE ACTIVATION IN LUNG DISEASE: Biphasic Granulocytic Inflammation And Bronchoconstriction Towards Serotonin Occurs Detached From Parenchymal Hyperresponsiveness In …
B Fuchs, MS Dearman, M Fredberg, A Smailagic, L Swedin
American Journal of Respiratory and Critical Care Medicine 189, 1, 2014
2014
Cellular pathology of allergic airway inflammatory responses to ovalbumin (OVA) following adoptive transfer of CD4+ T lymphocytes to naive rats
KJ Escott, M Dearman, M Foster, A Bahl
Journal of Allergy and Clinical Immunology 113 (2), S248, 2004
2004
Functional responses to MIP-1 alpha in isolated human peripheral blood eosinophils
MS Dearman, J Purdy, ME Leeson, AK Bahl
CLINICAL AND EXPERIMENTAL ALLERGY 31 (1), 159-159, 2001
2001
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