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Jason Drury
Jason Drury
Verified email at stjude.org
Title
Cited by
Cited by
Year
Human aldo–keto reductases: function, gene regulation, and single nucleotide polymorphisms
TM Penning, JE Drury
Archives of biochemistry and biophysics 464 (2), 241-250, 2007
3132007
Permeation and activation of the M2 ion channel of influenza A virus
JA Mould, JE Drury, SM Frings, UB Kaupp, A Pekosz, RA Lamb, LH Pinto
Journal of Biological Chemistry 275 (40), 31038-31050, 2000
1822000
Crystal structure of human liver Δ4-3-ketosteroid 5β-reductase (AKR1D1) and implications for substrate binding and catalysis
L Di Costanzo, JE Drury, TM Penning, DW Christianson
Journal of Biological Chemistry 283 (24), 16830-16839, 2008
732008
Inhibition of human steroid 5β-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex
JE Drury, L Di Costanzo, TM Penning, DW Christianson
Journal of Biological Chemistry 284 (30), 19786-19790, 2009
712009
Molecular basis of 1-deoxygalactonojirimycin arylthiourea binding to human α-galactosidase A: pharmacological chaperoning efficacy on Fabry disease mutants
Y Yu, T Mena-Barragan, K Higaki, JL Johnson, JE Drury, RL Lieberman, ...
ACS chemical biology 9 (7), 1460-1469, 2014
552014
Characterization of disease-related 5β-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency
JE Drury, R Mindnich, TM Penning
Journal of Biological Chemistry 285 (32), 24529-24537, 2010
512010
Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1)
M Chen, JE Drury, TM Penning
Steroids 76 (5), 484-490, 2011
492011
Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)
L Di Costanzo, JE Drury, DW Christianson, TM Penning
Molecular and cellular endocrinology 301 (1-2), 191-198, 2009
362009
Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector
BA Piras, JE Drury, CL Morton, Y Spence, TD Lockey, AC Nathwani, ...
Molecular Therapy-Methods & Clinical Development 3, 16015, 2016
262016
Conversion of Human Steroid 5β-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H EXAMPLE OF PERFECT ENZYME ENGINEERING
M Chen, JE Drury, DW Christianson, TM Penning
Journal of Biological Chemistry 287 (20), 16609-16622, 2012
192012
The effect of disease associated point mutations on 5β-reductase (AKR1D1) enzyme function
R Mindnich, JE Drury, TM Penning
Chemico-biological interactions 191 (1-3), 250-254, 2011
172011
Conversion of scFv peptide-binding specificity for crystal chaperone development
JC Pai, JA Culver, JE Drury, RS Motani, RL Lieberman, JA Maynard
Protein Engineering, Design & Selection 24 (5), 419-428, 2011
172011
Catalytic properties of intramembrane aspartyl protease substrate hydrolysis evaluated using a FRET peptide cleavage assay
SH Naing, KM Vukoti, JE Drury, JL Johnson, S Kalyoncu, SE Hill, ...
ACS chemical biology 10 (9), 2166-2174, 2015
152015
A*-3-Ketosteroid 53-Reductase (AKR1D1): Properties and Role in
JE Drury, T Penning
Enzymology and Molecular Biology of Carbonyl Metabolism 13, 332, 2007
3*2007
Structure–function relationship of the M2 ion channel of influenza A virus
JA Mould, K Shuck, JE Drury, SM Frings, UB Kaupp, A Pekosz, RA Lamb, ...
International Congress Series 1219, 389-396, 2001
12001
Abstract/Details
JE Drury, TM Penning
1*
Structural Analysis of the Change-of-Function E120H Mutation in Human Liver triangle (4)-3-Ketosteroid 5 beta-Reductase (AKR1D1).
M Chen, JE Drury, TM Penning, DW Christianson
ENDOCRINE REVIEWS 31 (3), 2010
2010
Structural Analysis of the Change-of-Function E120H Mutation in Human Liver Δ4-3-Ketosteroid 5β-Reductase (AKR1D1).
M Chen, JE Drury, TM Penning, DW Christianson
Posters I, P3-25-P3-25, 2010
2010
Expression, characterization, and structural analysis of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and its disease-related mutant P133R
JE Drury
University of Pennsylvania, 2009
2009
BIOL 16-Cortisone, progesterone and testosterone binding in the active site of delta (4)-3-ketosteroid 5 beta-reductase: A crystallographic study
L Di Costanzo, JE Drury, TM Penning, DW Christianson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 236, 2008
2008
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