| Glucose depletion rapidly inhibits translation initiation in yeast MP Ashe, SK De Long, AB Sachs Molecular biology of the cell 11 (3), 833-848, 2000 | 466 | 2000 |
| Global translational responses to oxidative stress impact upon multiple levels of protein synthesis D Shenton, JB Smirnova, JN Selley, K Carroll, SJ Hubbard, GD Pavitt, ... Journal of Biological Chemistry 281 (39), 29011-29021, 2006 | 443 | 2006 |
| Stress-dependent relocalization of translationally primed mRNPs to cytoplasmic granules that are kinetically and spatially distinct from P-bodies NP Hoyle, LM Castelli, SG Campbell, LEA Holmes, MP Ashe The Journal of cell biology 179 (1), 65-74, 2007 | 260 | 2007 |
| The yeast poly (A)-binding protein Pab1p stimulates in vitro poly (A)-dependent and cap-dependent translation by distinct mechanisms LJ Otero, MP Ashe, AB Sachs The EMBO Journal 18 (11), 3153-3163, 1999 | 165 | 1999 |
| The HIV-1 5′ LTR poly (A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site MP Ashe, LH Pearson, NJ Proudfoot The EMBO journal 16 (18), 5752-5763, 1997 | 157 | 1997 |
| Poly (A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site. MP Ashe, P Griffin, W James, NJ Proudfoot Genes & development 9 (23), 3008-3025, 1995 | 151 | 1995 |
| Gcn4 Is Required for the Response to Peroxide Stress in the Yeast Saccharomyces cerevisiae C Mascarenhas, LC Edwards-Ingram, L Zeef, D Shenton, MP Ashe, ... Molecular biology of the cell 19 (7), 2995-3007, 2008 | 130 | 2008 |
| Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways JB Smirnova, JN Selley, F Sanchez-Cabo, K Carroll, AA Eddy, ... Molecular and cellular biology 25 (21), 9340-9349, 2005 | 123 | 2005 |
| TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors JR Rohde, S Campbell, SA Zurita-Martinez, NS Cutler, M Ashe, ... Molecular and cellular biology 24 (19), 8332-8341, 2004 | 106 | 2004 |
| A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols MP Ashe, JW Slaven, SK De Long, S Ibrahimo, AB Sachs The EMBO journal 20 (22), 6464-6474, 2001 | 106 | 2001 |
| Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast C Lawless, RD Pearson, JN Selley, JB Smirnova, CM Grant, MP Ashe, ... BMC genomics 10, 1-20, 2009 | 101 | 2009 |
| Loss of translational control in yeast compromised for the major mRNA decay pathway LEA Holmes, SG Campbell, SK De Long, AB Sachs, MP Ashe Molecular and cellular biology 24 (7), 2998-3010, 2004 | 98 | 2004 |
| Global mRNA selection mechanisms for translation initiation J Costello, LM Castelli, W Rowe, CJ Kershaw, D Talavera, ... Genome biology 16 (1), 1-21, 2015 | 90 | 2015 |
| Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up … LM Castelli, J Lui, SG Campbell, W Rowe, LAH Zeef, LEA Holmes, ... Molecular biology of the cell 22 (18), 3379-3393, 2011 | 89 | 2011 |
| Adaptation to stress in yeast: to translate or not? CE Simpson, MP Ashe Biochemical Society Transactions 40 (4), 794-799, 2012 | 85 | 2012 |
| Stem-loop 1 of the U1 snRNP plays a critical role in the suppression of HIV-1 polyadenylation. MP Ashe, A Furger, NJ Proudfoot Rna 6 (2), 170-177, 2000 | 85 | 2000 |
| Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control SG Campbell, NP Hoyle, MP Ashe The Journal of cell biology 170 (6), 925-934, 2005 | 82 | 2005 |
| Granules harboring translationally active mRNAs provide a platform for P-body formation following stress J Lui, LM Castelli, M Pizzinga, CE Simpson, NP Hoyle, KL Bailey, ... Cell reports 9 (3), 944-954, 2014 | 64 | 2014 |
| Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins AG Cridge, LM Castelli, JB Smirnova, JN Selley, W Rowe, SJ Hubbard, ... Nucleic acids research 38 (22), 8039-8050, 2010 | 62 | 2010 |
| The mTOR-S6 kinase pathway promotes stress granule assembly AP Sfakianos, LE Mellor, YF Pang, P Kritsiligkou, H Needs, ... Cell Death & Differentiation 25 (10), 1766-1780, 2018 | 56 | 2018 |
Chris GrantProfessor of Biochemistry, University of ManchesterVerified email at manchester.ac.uk
