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Gary Brennan
Gary Brennan
Assistant Professor, University College Dublin
Verified email at ucd.ie
Title
Cited by
Cited by
Year
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis
RC McKiernan, EM Jimenez-Mateos, I Bray, T Engel, GP Brennan, T Sano, ...
PloS one 7 (5), e35921, 2012
1372012
The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes
S McClelland, GP Brennan, C Dubé, S Rajpara, S Iyer, C Richichi, ...
Elife 3, e01267, 2014
1312014
Dual and opposing roles of microRNA-124 in epilepsy are mediated through inflammatory and NRSF-dependent gene networks
GP Brennan, D Dey, Y Chen, KP Patterson, EJ Magnetta, AM Hall, ...
Cell reports 14 (10), 2402-2412, 2016
1122016
MicroRNAs as regulators of brain function and targets for treatment of epilepsy
GP Brennan, DC Henshall
Nature Reviews Neurology 16 (9), 506-519, 2020
1062020
Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy
R Raoof, S Bauer, H El Naggar, NMC Connolly, GP Brennan, E Brindley, ...
EBioMedicine 38, 127-141, 2018
982018
A microRNA‐129‐5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses
M Rajman, F Metge, R Fiore, S Khudayberdiev, A Aksoy‐Aksel, S Bicker, ...
The EMBO journal 36 (12), 1770-1787, 2017
942017
microRNAs in the pathophysiology of epilepsy
GP Brennan, DC Henshall
Neuroscience letters 667, 47-52, 2018
752018
Rapid, coordinate inflammatory responses after experimental febrile status epilepticus: implications for epileptogenesis
KP Patterson, GP Brennan, M Curran, E Kinney-Lang, C Dubé, F Rashid, ...
Eneuro 2 (5), 2015
592015
Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy
GP Brennan, TZ Baram, NP Poolos
Cold Spring Harbor Perspectives in Medicine, 2016
582016
Enduring memory impairments provoked by developmental febrile seizures are mediated by functional and structural effects of neuronal restrictive silencing factor
KP Patterson, JM Barry, MM Curran, A Singh-Taylor, G Brennan, ...
Journal of Neuroscience 37 (14), 3799-3812, 2017
562017
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy
MT Venø, CR Reschke, G Morris, NMC Connolly, J Su, Y Yan, T Engel, ...
Proceedings of the National Academy of Sciences 117 (27), 15977-15988, 2020
502020
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo
GP Brennan, EM Jimenez-Mateos, RC McKiernan, T Engel, G Tzivion, ...
PloS one 8 (1), e54491, 2013
472013
Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
GP Brennan, S Bauer, T Engel, EM Jimenez-Mateos, F Del Gallo, ...
Neurobiology of Disease 144, 105048, 2020
442020
A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22
T Engel, GP Brennan, A Sanz-Rodriguez, M Alves, E Beamer, O Watters, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (2), 255-266, 2017
382017
Regulatory Mechanisms of the RNA Modification m6A and Significance in Brain Function in Health and Disease
J Mathoux, DC Henshall, GP Brennan
Frontiers in cellular neuroscience 15, 671932, 2021
342021
Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures
VR Vangoor, CR Reschke, K Senthilkumar, LL Van De Haar, M De Wit, ...
Journal of Neuroscience 39 (26), 5064-5079, 2019
332019
Epigenetic principles underlying epileptogenesis and epilepsy syndromes
K Conboy, DC Henshall, GP Brennan
Neurobiology of disease 148, 105179, 2021
292021
Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury
T Engel, J Martinez-Villarreal, C Henke, EM Jimenez-Mateos, ...
Molecular neurodegeneration 12, 1-17, 2017
272017
The role of Sirt1 in epileptogenesis
AM Hall, GP Brennan, TM Nguyen, A Singh-Taylor, HS Mun, MJ Sargious, ...
Eneuro 4 (1), 2017
252017
Altered biogenesis and microRNA content of hippocampal exosomes following experimental status epilepticus
A Batool, TDM Hill, NT Nguyen, E Langa, M Diviney, C Mooney, ...
Frontiers in Neuroscience 13, 1404, 2020
242020
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