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Mariella Gruber Filbin
Mariella Gruber Filbin
Dana-Farber Cancer Institute, Boston Childrens Hospital, Harvard Medical SChool
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
21672018
An integrative model of cellular states, plasticity, and genetics for glioblastoma
C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ...
Cell 178 (4), 835-849. e21, 2019
17022019
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ...
Nature 539 (7628), 309-313, 2016
9752016
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ...
Science 355 (6332), eaai8478, 2017
8512017
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
5502018
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
RG Majzner, S Ramakrishna, KW Yeom, S Patel, H Chinnasamy, ...
Nature 603 (7903), 934-941, 2022
4372022
Resolving medulloblastoma cellular architecture by single-cell genomics
V Hovestadt, KS Smith, L Bihannic, MG Filbin, MKL Shaw, A Baumgartner, ...
Nature 572 (7767), 74-79, 2019
3332019
Stalled developmental programs at the root of pediatric brain tumors
S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ...
Nature genetics 51 (12), 1702-1713, 2019
1902019
Developmental origins and emerging therapeutic opportunities for childhood cancer
M Filbin, M Monje
Nature medicine 25 (3), 367-376, 2019
1542019
Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma
GL Lin, S Nagaraja, MG Filbin, ML Suvà, H Vogel, M Monje
Acta neuropathologica communications 6, 1-12, 2018
1542018
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities
M Gruber Filbin, SK Dabral, MF Pazyra-Murphy, S Ramkissoon, AL Kung, ...
Nature medicine 19 (11), 1518-1523, 2013
1432013
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG
JN Anastas, BM Zee, JH Kalin, M Kim, R Guo, S Alexandrescu, MA Blanco, ...
Cancer cell 36 (5), 528-544. e10, 2019
1392019
Histone variant and cell context determine H3K27M reprogramming of the enhancer landscape and oncogenic state
S Nagaraja, MA Quezada, SM Gillespie, M Arzt, JJ Lennon, PJ Woo, ...
Molecular cell 76 (6), 965-980. e12, 2019
1312019
Single-cell RNA-seq reveals cellular hierarchies and impaired developmental trajectories in pediatric ependymoma
J Gojo, B Englinger, L Jiang, JM Hübner, MKL Shaw, OA Hack, ...
Cancer cell 38 (1), 44-59. e9, 2020
1202020
Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis
CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ...
Cell 183 (6), 1617-1633. e22, 2020
1152020
Molecular and clinicopathologic features of gliomas harboring NTRK fusions
M Torre, V Vasudevaraja, J Serrano, M DeLorenzo, S Malinowski, ...
Acta Neuropathologica Communications 8, 1-14, 2020
982020
Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors
SH Ramkissoon, P Bandopadhayay, J Hwang, LA Ramkissoon, ...
Neuro-oncology 19 (7), 986-996, 2017
922017
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
I Liu, L Jiang, ER Samuelsson, S Marco Salas, A Beck, OA Hack, D Jeong, ...
Nature Genetics 54 (12), 1881-1894, 2022
612022
Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma
N Manoharan, J Choi, C Chordas, MA Zimmerman, J Scully, J Clymer, ...
Journal of Neuro-Oncology 149, 253-262, 2020
572020
Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
ZJ Reitman, BR Paolella, G Bergthold, K Pelton, S Becker, R Jones, ...
Nature communications 10 (1), 3731, 2019
552019
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