| Direct protein-lipid interactions shape the conformational landscape of secondary transporters C Martens, M Shekhar, AJ Borysik, AM Lau, E Reading, E Tajkhorshid, ... Nature communications 9 (1), 4151, 2018 | 130 | 2018 |
| Structural lipids enable the formation of functional oligomers of the eukaryotic purine symporter UapA E Pyle, AC Kalli, S Amillis, Z Hall, AM Lau, AC Hanyaloglu, G Diallinas, ... Cell chemical biology 25 (7), 840-848. e4, 2018 | 78 | 2018 |
| Deuteros 2.0: peptide-level significance testing of data from hydrogen deuterium exchange mass spectrometry AM Lau, J Claesen, K Hansen, A Politis Bioinformatics 37 (2), 270-272, 2021 | 69 | 2021 |
| Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry AMC Lau, Z Ahdash, C Martens, A Politis Bioinformatics 35 (17), 3171-3173, 2019 | 66 | 2019 |
| Surface accessibility and dynamics of macromolecular assemblies probed by covalent labeling mass spectrometry and integrative modeling C Schmidt, JA Macpherson, AM Lau, KW Tan, F Fraternali, A Politis Analytical chemistry 89 (3), 1459-1468, 2017 | 62 | 2017 |
| Integrating hydrogen–deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins C Martens, M Shekhar, AM Lau, E Tajkhorshid, A Politis Nature protocols 14 (11), 3183-3204, 2019 | 52 | 2019 |
| Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome SV Faull, AMC Lau, C Martens, Z Ahdash, K Hansen, H Yebenes, ... Nature communications 10 (1), 3814, 2019 | 49 | 2019 |
| A mass‐spectrometry‐based modelling workflow for accurate prediction of IgG antibody conformations in the gas phase K Hansen, AM Lau, K Giles, JM McDonnell, WB Struwe, BJ Sutton, ... Angewandte Chemie 130 (52), 17440-17445, 2018 | 49 | 2018 |
| Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterized proteins SM Kandathil, JG Greener, AM Lau, DT Jones Proceedings of the National Academy of Sciences 119 (4), e2113348119, 2022 | 47* | 2022 |
| Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB E Reading, Z Ahdash, C Fais, V Ricci, X Wang-Kan, E Grimsey, J Stone, ... Nature communications 11 (1), 5565, 2020 | 43 | 2020 |
| Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter R Jia, C Martens, M Shekhar, S Pant, GA Pellowe, AM Lau, HE Findlay, ... Nature communications 11 (1), 6162, 2020 | 39 | 2020 |
| Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry A Stützer, LM Welp, M Raabe, T Sachsenberg, C Kappert, A Wulf, AM Lau, ... Nature communications 11 (1), 5250, 2020 | 34 | 2020 |
| Mechanistic insight into the assembly of the HerA–NurA helicase–nuclease DNA end resection complex Z Ahdash, AM Lau, RT Byrne, K Lammens, A Stüetzer, H Urlaub, PJ Booth, ... Nucleic Acids Research 45 (20), 12025-12038, 2017 | 29 | 2017 |
| Zinc-induced oligomerization of zinc α2 glycoprotein reveals multiple fatty acid-binding sites H Zahid, L Miah, AM Lau, L Brochard, D Hati, TTT Bui, AF Drake, J Gor, ... Biochemical Journal 473 (1), 43-54, 2016 | 29 | 2016 |
| Structural predictions of the functions of membrane proteins from HDX-MS AM Lau, R Jia, RT Bradshaw, A Politis Biochemical Society Transactions, 2020 | 10 | 2020 |
| Ea-538 monn Reading, Emad Tajkhorshid, Paula J. Booth, and Argyris Politis. 539 Direct protein-lipid interactions shape the conformational landscape of 540 secondary transporters C Martens, M Shekhar, AJ Borysik, AM Lau Nature Communications 9 (1), 1-12, 0 | 8 | |
| Machine learning methods for predicting protein structure from single sequences SM Kandathil, AM Lau, DT Jones Current Opinion in Structural Biology 81, 102627, 2023 | 7 | 2023 |
| Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding AM Lau, H Zahid, J Gor, SJ Perkins, AR Coker, LC McDermott Biochemical Journal 476 (19), 2815-2834, 2019 | 7 | 2019 |
| Analyzing protein architectures and protein-ligand complexes by integrative structural mass spectrometry Z Ahdash, AM Lau, C Martens, A Politis JoVE (Journal of Visualized Experiments), e57966, 2018 | 6 | 2018 |
| Integrative Mass Spectrometry–Based Approaches for Modeling Macromolecular Assemblies AM Lau, A Politis Multiprotein Complexes: Methods and Protocols, 221-241, 2021 | 5 | 2021 |
Argyris PolitisGroup Leader, EPSRC Research Fellow, University of ManchesterVerified email at manchester.ac.uk
