Wolfgang A Linke
Wolfgang A Linke
Professor of Physiology, University of Münster
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Cited by
Cited by
Cardioprotection and lifespan extension by the natural polyamine spermidine
T Eisenberg, M Abdellatif, S Schroeder, U Primessnig, S Stekovic, T Pendl, ...
Nature medicine 22 (12), 1428-1438, 2016
Myocardial structure and function differ in systolic and diastolic heart failure
L van Heerebeek, A Borbély, HWM Niessen, JGF Bronzwaer, ...
Circulation 113 (16), 1966-1973, 2006
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ...
Science 349 (6251), 982-986, 2015
Reverse engineering of the giant muscle protein titin
H Li, WA Linke, AF Oberhauser, M Carrion-Vazquez, JG Kerkvliet, H Lu, ...
Nature 418 (6901), 998-1002, 2002
Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair
M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, ...
Circulation 135 (19), 1832-1847, 2017
Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction
C Franssen, S Chen, A Unger, HI Korkmaz, GW De Keulenaer, C Tschöpe, ...
JACC: Heart Failure 4 (4), 312-324, 2016
Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs
M Krüger, S Kötter, A Grützner, P Lang, C Andresen, MM Redfield, E Butt, ...
Circulation Research 104 (1), 87-94, 2009
Titin isoform switch in ischemic human heart disease
C Neagoe, M Kulke, F del Monte, JK Gwathmey, PP de Tombe, RJ Hajjar, ...
Circulation 106 (11), 1333-1341, 2002
The translational landscape of the human heart
S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ...
Cell 178 (1), 242-260. e29, 2019
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts
I Makarenko, CA Opitz, MC Leake, C Neagoe, M Kulke, JK Gwathmey, ...
Circulation research 95 (7), 708-716, 2004
Gigantic business: titin properties and function through thick and thin
WA Linke, N Hamdani
Circulation research 114 (6), 1052-1068, 2014
Sense and stretchability: the role of titin and titin-associated proteins in myocardial stress-sensing and mechanical dysfunction
WA Linke
Cardiovascular research 77 (4), 637-648, 2008
Differential cardiac remodeling in preload versus afterload
K Toischer, AG Rokita, B Unsöld, W Zhu, G Kararigas, S Sossalla, ...
Circulation 122 (10), 993-1003, 2010
Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles
LG Prado, I Makarenko, C Andresen, M Krüger, CA Opitz, WA Linke
The Journal of general physiology 126 (5), 461-480, 2005
Towards a molecular understanding of the elasticity of titin
WA Linke, M Ivemeyer, N Olivieri, B Kolmerer, CJ Rüegg, S Labeit
Journal of molecular biology 261 (1), 62-71, 1996
The giant protein titin: emerging roles in physiology and pathophysiology
S Labeit, B Kolmerer, WA Linke
Circulation Research 80 (2), 290-294, 1997
Myocardial titin hypophosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model
N Hamdani, C Franssen, A Lourenço, I Falcăo-Pires, D Fontoura, S Leite, ...
Circulation: Heart Failure 6 (6), 1239-1249, 2013
I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure
WA Linke, DE Rudy, T Centner, M Gautel, C Witt, S Labeit, CC Gregorio
The Journal of cell biology 146 (3), 631-644, 1999
Nature of PEVK-titin elasticity in skeletal muscle
WA Linke, M Ivemeyer, P Mundel, MR Stockmeier, B Kolmerer
Proceedings of the National Academy of Sciences 95 (14), 8052-8057, 1998
Titin-truncating variants affect heart function in disease cohorts and the general population
S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, ...
Nature genetics 49 (1), 46-53, 2017
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