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Dr. Ahmad Al-Khliefat
Dr. Ahmad Al-Khliefat
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Detection of long repeat expansions from PCR-free whole-genome sequence data
E Dolzhenko, JJ Van Vugt, RJ Shaw, MA Bekritsky, M Van Blitterswijk, ...
Genome research 27 (11), 1895-1903, 2017
3182017
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ...
Nature genetics 53 (12), 1636-1648, 2021
2752021
A multicentre validation study of the diagnostic value of plasma neurofilament light
NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ...
Nature communications 12 (1), 3400, 2021
2712021
Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study
T Fang, A Al Khleifat, JH Meurgey, A Jones, PN Leigh, G Bensimon, ...
The Lancet Neurology 17 (5), 416-422, 2018
2372018
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
2232021
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis
European Journal of Human Genetics 26 (10), 1537-1546, 2018
1322018
What causes amyotrophic lateral sclerosis?
S Martin, A Al Khleifat, A Al-Chalabi
F1000Research 6, 2017
1252017
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein
SMK Farhan, DP Howrigan, LE Abbott, JR Klim, SD Topp, AE Byrnes, ...
Nature neuroscience 22 (12), 1966-1974, 2019
1102019
C9orf72 intermediate expansions of 24–30 repeats are associated with ALS
A Iacoangeli, A Al Khleifat, AR Jones, W Sproviero, A Shatunov, ...
Acta neuropathologica communications 7, 1-7, 2019
1002019
A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK
S Morgan, A Shatunov, W Sproviero, AR Jones, M Shoai, D Hughes, ...
Brain 140 (6), 1611-1618, 2017
952017
Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial
N Riva, G Mora, G Sorarù, C Lunetta, OE Ferraro, Y Falzone, L Leocani, ...
The Lancet Neurology 18 (2), 155-164, 2019
892019
Comparison of the King’s and MiToS staging systems for ALS
T Fang, A Al Khleifat, DR Stahl, C Lazo La Torre, C Murphy, ...
Amyotrophic lateral sclerosis and frontotemporal degeneration 18 (3-4), 227-232, 2017
852017
Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias
PR Mehta, AR Jones, S Opie-Martin, A Shatunov, A Iacoangeli, ...
Journal of Neurology, Neurosurgery & Psychiatry 90 (3), 268-271, 2019
602019
Association of variants in the SPTLC1 gene with juvenile amyotrophic lateral sclerosis
JO Johnson, R Chia, DE Miller, R Li, R Kumaran, Y Abramzon, ...
JAMA neurology 78 (10), 1236-1248, 2021
542021
Genome-wide meta-analysis finds the ACSL5-ZDHHC6 locus is associated with ALS and links weight loss to the disease genetics
A Iacoangeli, T Lin, A Al Khleifat, AR Jones, S Opie-Martin, JRI Coleman, ...
Cell Reports 33 (4), 2020
472020
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS
PJ Hop, RAJ Zwamborn, E Hannon, GL Shireby, MF Nabais, EM Walker, ...
Science translational medicine 14 (633), eabj0264, 2022
462022
A standard operating procedure for King’s ALS clinical staging
R Balendra, A Al Khleifat, T Fang, A Al-Chalabi
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (3-4), 159-164, 2019
432019
Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis
A Al Khleifat, A Iacoangeli, JJFA Van Vugt, H Bowles, M Moisse, ...
NPJ genomic medicine 7 (1), 8, 2022
302022
Whole-genome sequencing reveals that variants in the interleukin 18 receptor accessory protein 3′ UTR protect against ALS
C Eitan, A Siany, E Barkan, T Olender, KR van Eijk, M Moisse, ...
Nature neuroscience 25 (4), 433-445, 2022
252022
The impact of age on genetic testing decisions in amyotrophic lateral sclerosis
PR Mehta, A Iacoangeli, S Opie-Martin, JJFA van Vugt, A Al Khleifat, ...
Brain 145 (12), 4440-4447, 2022
232022
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