cathal mahon
cathal mahon
Denali Therapeutics
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Global landscape of HIV–human protein complexes
S Jaeger, P Cimermancic, N Gulbahce, JR Johnson, KE McGovern, ...
Nature 481 (7381), 365-370, 2012
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
S Jäger, DY Kim, JF Hultquist, K Shindo, RS LaRue, E Kwon, M Li, ...
Nature 481 (7381), 371-375, 2012
GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data
ME Fahey, MJ Bennett, C Mahon, S Jäger, L Pache, D Kumar, A Shapiro, ...
Bmc Bioinformatics 12 (1), 1-13, 2011
Cullin E3 ligases and their rewiring by viral factors
C Mahon, NJ Krogan, CS Craik, E Pick
Biomolecules 4 (4), 897-930, 2014
Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii
CS Mahon, AJ O'Donoghue, DH Goetz, PG Murray, CS Craik, MG Tuohy
Microbiology 155 (Pt 11), 3673, 2009
Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii
AJ O'Donoghue, CS Mahon, DH Goetz, JM O'Malley, DM Gallagher, ...
Journal of Biological Chemistry 283 (43), 29186-29195, 2008
Restriction of human polyomavirus BK virus DNA replication in murine cells and extracts
C Mahon, B Liang, I Tikhanovich, JR Abend, MJ Imperiale, HP Nasheuer, ...
Journal of virology 83 (11), 5708-5717, 2009
Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr
AB DePaula-Silva, PA Cassiday, J Chumley, A Bosque, ...
Virology 477, 10-17, 2015
Talaromyces emersonii enzyme systems
MG Tuohy, PG Murray, TC Gilleran, CM Collins, FJ Reen, LP McLoughlin, ...
US Patent App. 12/278,915, 2010
Comparison of DNA replication in Xenopus laevis and Simian Virus 40
M Oehlmann, C Mahon, HP Nasheuer
Advances in Molecular Oncology, 3-16, 2007
Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region
K Schlepckow, KM Monroe, G Kleinberger, L Cantuti‐Castelvetri, ...
EMBO molecular medicine 12 (4), e11227, 2020
Blockage of HBV virus replication and inhibition of cccDNA establishment by Core protein Allosteric modifiers (CpAMs)
Q Huang, Y Zong, A Mercier, R Kumar, C Mahon, Y Zhou, PC Li, L Guo, ...
Hepatology 63 (1 SUPP), 937A-938A, 2016
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ...
Science Translational Medicine 12 (545), 2020
Preclinical Characterization of Potent Core Protein Assembly Modulators for the Treatment of Chronic Hepatitis B
Q Huang, A Mercier, Y Zhou, K Henne, GR Kumar, S Sun, L Guo, J Liu, ...
Journal of Hepatology 64 (2), S584, 2016
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, ...
Science Translational Medicine 12 (545), 2020
Improved brain uptake and efficacy of iduronate 2-sulfatase with the enzyme transport vehicle
AG Henry, MS Kariolis, JC Ullman, JA Getz, A Arguello, C Mahon, J Wang, ...
Molecular Genetics and Metabolism 126 (2), S72, 2019
Novel FACS based method demonstrates CNS cell-type distribution and efficacy of a BBB penetrant ERT in a mouse model of MPS II
JC Ullman, AA Nugent, A Arguello, A Bhalla, T Sandmann, S Lianoglou, ...
Molecular Genetics and Metabolism 129 (2), S155, 2020
Brain delivery and efficacy of an intravenously-administered lysosomal enzyme using a blood-brain barrier transport vehicle
AG Henry, J Ullman, A Arguello, J Getz, A Bhalla, C Mahon, J Wang, ...
Molecular Genetics and Metabolism 129 (2), S72, 2020
Fusion proteins comprising enzyme replacement therapy enzymes
A Henry, M Kariolis, C Mahon, AP Silverman, A Srivastava
US Patent App. 16/355,339, 2019
Cullin E3 ligases and their rewiring by viral factors.
N Krogan, C Craik, C Mahon, NJ Krogan, CS Craik, E Pick
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