Alfredo Iacoangeli
Title
Cited by
Cited by
Year
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
2742018
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis
Project MinE ALS Sequencing Consortium
European Journal of Human Genetics 26 (10), 1537, 2018
612018
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein
SMK Farhan, DP Howrigan, LE Abbott, JR Klim, SD Topp, AE Byrnes, ...
Nature neuroscience 22 (12), 1966-1974, 2019
452019
C9orf72 intermediate expansions of 24–30 repeats are associated with ALS
A Iacoangeli, A Al Khleifat, AR Jones, W Sproviero, A Shatunov, ...
Acta neuropathologica communications 7 (1), 1-7, 2019
332019
The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public
RAA van der Spek, W Van Rheenen, SL Pulit, KP Kenna, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (5-6), 432-440, 2019
292019
PepComposer: computational design of peptides binding to a given protein surface
A Obarska-Kosinska, A Iacoangeli, R Lepore, A Tramontano
Nucleic acids research 44 (W1), W522-W528, 2016
262016
Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias
PR Mehta, AR Jones, S Opie-Martin, A Shatunov, A Iacoangeli, ...
Journal of Neurology, Neurosurgery & Psychiatry 90 (3), 268-271, 2019
192019
Targeted genetic screen in amyotrophic lateral sclerosis reveals novel genetic variants with synergistic effect on clinical phenotype
J Cooper-Knock, H Robins, I Niedermoser, M Wyles, PR Heath, ...
Frontiers in molecular neuroscience 10, 370, 2017
182017
Genomic and phenomic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
medRxiv, 2020
142020
Association of NIPA1 repeat expansions with amyotrophic lateral sclerosis in a large international cohort
GHP Tazelaar, AM Dekker, JJFA van Vugt, RA van der Spek, ...
Neurobiology of aging 74, 234. e9-234. e15, 2019
142019
ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization
GHP Tazelaar, S Boeynaems, M De Decker, JJFA van Vugt, L Kool, ...
Brain communications 2 (2), fcaa064, 2020
132020
Reconsidering the causality of TIA1 mutations in ALS
RA Van Der Spek, W Van Rheenen, SL Pulit, KP Kenna, N Ticozzi, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19 (1-2), 1-3, 2018
122018
Genome-wide meta-analysis finds the ACSL5-ZDHHC6 Locus is associated with als and links weight loss to the disease genetics
A Iacoangeli, T Lin, A Al Khleifat, AR Jones, S Opie-Martin, JRI Coleman, ...
Cell reports 33 (4), 108323, 2020
102020
Telomere length is greater in ALS than in controls: a whole genome sequencing study
A Al Khleifat, A Iacoangeli, A Shatunov, T Fang, W Sproviero, AR Jones, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (3-4), 229-234, 2019
82019
A knowledge-based machine learning approach to gene prioritisation in amyotrophic lateral sclerosis
DM Bean, A Al-Chalabi, RJB Dobson, A Iacoangeli
Genes 11 (6), 668, 2020
72020
DNAscan: personal computer compatible NGS analysis, annotation and visualisation
A Iacoangeli, A Al Khleifat, W Sproviero, A Shatunov, AR Jones, ...
BMC bioinformatics 20 (1), 1-10, 2019
7*2019
UK case control study of smoking and risk of amyotrophic lateral sclerosis
S Opie-Martin, A Jones, A Iacoangeli, A Al-Khleifat, M Oumar, PJ Shaw, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21 (3-4), 222-227, 2020
42020
ALSgeneScanner: a pipeline for the analysis and interpretation of DNA sequencing data of ALS patients
A Iacoangeli, A Al Khleifat, W Sproviero, A Shatunov, AR Jones, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (3-4), 207-215, 2019
42019
Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
W van Rheenen, R van der Spek, M Bakker, L van den Berg, J Veldink, ...
32021
Rare variant burden analysis within enhancers identifies CAV1 as an ALS risk gene
J Cooper-Knock, S Zhang, KP Kenna, T Moll, JP Franklin, S Allen, ...
Cell Reports 34 (5), 2021
32021
The system can't perform the operation now. Try again later.
Articles 1–20