The health-e-AME faith-based physical activity initiative: Description and baseline findings S Wilcox, M Laken, T Anderson, M Bopp, D Bryant, R Carter, O Gethers, ... Health Promotion Practice 8 (1), 69-78, 2007 | 87 | 2007 |
Biophysical and computational methods to analyze amino acid interaction networks in proteins KF O'Rourke, SD Gorman, DD Boehr Computational and structural biotechnology journal 14, 245-251, 2016 | 63 | 2016 |
Amino Acid Networks in a (β/α)8 Barrel Enzyme Change during Catalytic Turnover JM Axe, EM Yezdimer, KF O’Rourke, NE Kerstetter, W You, CA Chang, ... Journal of the American Chemical Society 136 (19), 6818-6821, 2014 | 54 | 2014 |
Engineered control of enzyme structural dynamics and function DD Boehr, RN D'Amico, KF O'Rourke Protein Science 27 (4), 825-838, 2018 | 43 | 2018 |
Assigning methyl resonances for protein solution-state NMR studies SD Gorman, D Sahu, KF O'Rourke, DD Boehr Methods 148, 88-99, 2018 | 26 | 2018 |
Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase JM Axe, KF O'Rourke, NE Kerstetter, EM Yezdimer, YM Chan, A Chasin, ... Protein Science 24 (4), 484-494, 2015 | 23 | 2015 |
Loop‐loop interactions govern multiple steps in indole‐3‐glycerol phosphate synthase catalysis MJ Zaccardi, KF O'Rourke, EM Yezdimer, LJ Loggia, S Woldt, DD Boehr Protein Science 23 (3), 302-311, 2014 | 19 | 2014 |
Controlling Active Site Loop Dynamics in the (β/α)8 Barrel Enzyme Indole-3-Glycerol Phosphate Synthase KF O’Rourke, AM Jelowicki, DD Boehr Catalysts 6 (9), 129, 2016 | 14 | 2016 |
Coordinated network changes across the catalytic cycle of alpha tryptophan synthase KF O'Rourke, D Sahu, YK Bosken, RN D'Amico, AC Chia-en, DD Boehr Structure 27 (9), 1405-1415. e5, 2019 | 12 | 2019 |
Substitution of a surface-exposed residue involved in an allosteric network enhances tryptophan synthase function in cells RN D’Amico, YK Bosken, KF O’Rourke, AM Murray, W Admasu, ... Frontiers in Molecular Biosciences 8, 679915, 2021 | 9 | 2021 |
Distinct conformational dynamics and allosteric networks in alpha tryptophan synthase during active catalysis KF O'Rourke, RN D'Amico, D Sahu, DD Boehr Protein Science 30 (3), 543-557, 2021 | 6 | 2021 |
Millisecond timescale motions connect amino acid interaction networks in alpha tryptophan synthase KF O'Rourke, JM Axe, RN D'Amico, D Sahu, DD Boehr Frontiers in Molecular Biosciences 5, 92, 2018 | 6 | 2018 |
Allosteric networks regulate function in multi‐enzyme complexes DD Boehr, R D'Amico, K O'Rourke, Y Bosken, D Sahu, C Chang The FASEB Journal 36, 2022 | | 2022 |
A surface‐exposed, network substitution results in a gain‐of‐function in tryptophan synthase6. 5.0 RN D’Amico, KF O’Rourke, Y Bosken, AM Murray, CA Chang, DD Boehr The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
The Evolution of Dynamic Amino Acid Interaction Networks Around the Catalytic Cycle of a Tryptophan Synthase D Boehr, K O'Rourke, R D'Amico, D Sahu PROTEIN SCIENCE 27, 19-20, 2018 | | 2018 |
The evolution of dynamic amino acid interaction networks around the catalytic cycle of α tryptophan synthase DD Boehr, KF O'Rourke, RN D'Amico, D Sahu The FASEB Journal 32, 527.6-527.6, 2018 | | 2018 |
Amino acid networks in enzyme catalysis D Boehr, KF O'Rourke, JM Axe, D Sahu, R D'Amico The FASEB Journal 31, 273.1-273.1, 2017 | | 2017 |
Conformational Dynamics and Long-Range Interactions in Tryptophan Biosynthetic Enzymes KF O'Rourke The Pennsylvania State University, 2017 | | 2017 |
Tuning Catalytic Activity by Perturbing Amino Acid Networks in a (beta/alpha) 8 Barrel Enzyme K O'Rourke PROTEIN SCIENCE 25, 84-84, 2016 | | 2016 |
Controlling Active Site Loop Dynamics in the (β/α) 8 Barrel Enzyme Indole-3-Glycerol Phosphate Synthase. AM Jelowicki, DD Boehr, KF O'Rourke Catalysts (2073-4344) 6 (9), 2016 | | 2016 |