Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2032 | 2013 |
Ionization− reactivity relationships for cysteine thiols in polypeptides G Bulaj, T Kortemme, DP Goldenberg Biochemistry 37 (25), 8965-8972, 1998 | 491 | 1998 |
Formation of disulfide bonds in proteins and peptides G Bulaj Biotechnology advances 23 (1), 87-92, 2005 | 305 | 2005 |
Conotoxins and the posttranslational modification of secreted gene products O Buczek, G Bulaj, BM Olivera Cellular and Molecular Life Sciences CMLS 62, 3067-3079, 2005 | 285 | 2005 |
Conus venoms-a rich source of peptide-based therapeutics TS Han, RW Teichert, BM Olivera, G Bulaj Current pharmaceutical design 14 (24), 2462-2479, 2008 | 230 | 2008 |
Converting peptides into drug leads by lipidation L Zhang, G Bulaj Current medicinal chemistry 19 (11), 1602-1618, 2012 | 211 | 2012 |
Conotoxins-new vistas for peptide therapeutics RM Jones, G Bulaj Current pharmaceutical design 6 (12), 1249-1285, 2000 | 170 | 2000 |
Structure/function characterization of μ-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels MM Zhang, BR Green, P Catlin, B Fiedler, L Azam, A Chadwick, H Terlau, ... Journal of Biological Chemistry 282 (42), 30699-30706, 2007 | 164 | 2007 |
μ-Conotoxins that differentially block sodium channels NaV1. 1 through 1.8 identify those responsible for action potentials in sciatic nerve MJ Wilson, D Yoshikami, L Azam, J Gajewiak, BM Olivera, G Bulaj, ... Proceedings of the National Academy of Sciences 108 (25), 10302-10307, 2011 | 152 | 2011 |
Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels G Bulaj, PJ West, JE Garrett, M Watkins, MM Zhang, RS Norton, BJ Smith, ... Biochemistry 44 (19), 7259-7265, 2005 | 143 | 2005 |
Efficient oxidative folding of conotoxins and the radiation of venomous cone snails G Bulaj, O Buczek, I Goodsell, EC Jimenez, J Kranski, JS Nielsen, ... Proceedings of the National Academy of Sciences 100 (suppl_2), 14562-14568, 2003 | 128 | 2003 |
Folding of Conotoxins: Formation of the Native Disulfide Bridges During Chemical Synthesis and Biosynthesis of Conus Peptides G Bulaj, BM Olivera Antioxidants & redox signaling 10 (1), 141-156, 2008 | 127 | 2008 |
Isolation and Characterization of a Novel ConusPeptide with Apparent Antinociceptive Activity JM McIntosh, GO Corpuz, RT Layer, JE Garrett, JD Wagstaff, G Bulaj, ... Journal of Biological Chemistry 275 (42), 32391-32397, 2000 | 118 | 2000 |
Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide O Buczek, D Yoshikami, G Bulaj, EC Jimenez, BM Olivera Journal of Biological Chemistry 280 (6), 4247-4253, 2005 | 117 | 2005 |
Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst JA McIntosh, CR Robertson, V Agarwal, SK Nair, GW Bulaj, EW Schmidt Journal of the American Chemical Society 132 (44), 15499-15501, 2010 | 116 | 2010 |
μ-Conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons PJ West, G Bulaj, JE Garrett, BM Olivera, D Yoshikami Biochemistry 41 (51), 15388-15393, 2002 | 114 | 2002 |
Synthetic μO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1. 8 and has a long-lasting analgesic activity G Bulaj, MM Zhang, BR Green, B Fiedler, RT Layer, S Wei, JS Nielsen, ... Biochemistry 45 (23), 7404-7414, 2006 | 104 | 2006 |
Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads VD Twede, G Miljanich, BM Olivera, G Bulaj Current opinion in drug discovery & development 12 (2), 231, 2009 | 100 | 2009 |
Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins A Walewska, MM Zhang, JJ Skalicky, D Yoshikami, BM Olivera, G Bulaj Angewandte Chemie 121 (12), 2255-2258, 2009 | 95 | 2009 |
Structure and Sodium Channel Activity of an Excitatory I1-Superfamily Conotoxin, O Buczek, D Wei, JJ Babon, X Yang, B Fiedler, P Chen, D Yoshikami, ... Biochemistry 46 (35), 9929-9940, 2007 | 93 | 2007 |