An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells RD Jones, Y Qian, V Siciliano, B DiAndreth, J Huh, R Weiss, ... Nature communications 11 (1), 5690, 2020 | 82 | 2020 |
Context-aware synthetic biology by controller design: Engineering the mammalian cell N Shakiba, RD Jones, R Weiss, D Del Vecchio Cell systems 12 (6), 561-592, 2021 | 40 | 2021 |
A ‘poly-transfection’method for rapid, one-pot characterization and optimization of genetic systems JJ Gam, B DiAndreth, RD Jones, J Huh, R Weiss Nucleic Acids Research 47 (18), e106-e106, 2019 | 38 | 2019 |
miRNA sensitivity to Drosha levels correlates with pre-miRNA secondary structure H Sperber, A Beem, S Shannon, R Jones, P Banik, Y Chen, S Ku, ... Rna 20 (5), 621-631, 2014 | 34 | 2014 |
Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles RD Jones, Y Qian, K Ilia, B Wang, MT Laub, D Del Vecchio, R Weiss Nature communications 13 (1), 1720, 2022 | 25 | 2022 |
Effects of antioxidants and pro-oxidants on cytotoxicity of dihydroartemisinin to Molt-4 human leukemia cells T Gerhardt, R Jones, J Park, R Lu, HW Chan, Q Fang, N Singh, H Lai Anticancer Research 35 (4), 1867-1871, 2015 | 25 | 2015 |
Principles of synthetic biology: a MOOC for an emerging field DA Anderson, RD Jones, AP Arkin, R Weiss Synthetic Biology 4 (1), ysz010, 2019 | 11 | 2019 |
Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies H Kaul, N Werschler, RD Jones, MM Siu, M Tewary, A Hagner, J Ostblom, ... Stem cell reports 18 (1), 377-393, 2023 | 9 | 2023 |
Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells L Prochazka, YS Michaels, C Lau, RD Jones, M Siu, T Yin, D Wu, E Jang, ... Molecular Systems Biology 18 (11), e10886, 2022 | 5* | 2022 |
Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts K Ilia, N Shakiba, T Bingham, RD Jones, MM Kaminski, E Aravera, ... Science Advances 9 (48), eadg8495, 2023 | 4* | 2023 |
Single cell HaloChip assay on paper for point-of-care diagnosis L Ma, Y Qiao, R Jones, N Singh, M Su Analytical and bioanalytical chemistry 408, 7753-7759, 2016 | 4 | 2016 |
Sex biased human thymic architecture guides T cell development through spatially defined niches LN Stankiewicz, K Salim, EA Flaschner, YX Wang, JM Edgar, BZB Lin, ... bioRxiv, 2023 | 3 | 2023 |
Rapid Development of Cell State Identification Circuits with Poly-Transfection N Wauford, R Jones, C Van De Mark, R Weiss JoVE (Journal of Visualized Experiments), e64793, 2023 | 1 | 2023 |
A tunable phosphorylation-based feedback controller of mammalian gene expression RD Jones, Y Qian, D Del Vecchio, R Weiss US Patent App. 18/039,583, 2024 | | 2024 |
Phosphorylation-based mirna sensor R Weiss, RD Jones, J Huh US Patent App. 17/811,593, 2023 | | 2023 |
Selected Abstract: Integrating Synthetic Biology and Niche Engineering to Produce TCR-and CAR-T Cells from Pluripotent Stem Cells RD Jones 10th International Mammalian Synthetic Biology Workshop, 2023 | | 2023 |
Engineered incoherent feed forward loop and uses thereof R Weiss, RD Jones, BE DiAndreth, D Del Vecchio, Y Qian US Patent App. 17/153,276, 2021 | | 2021 |
Engineered herpes simplex virus-1 (hsv-1) vectors and uses thereof R Weiss, MH Foley, J Huh, RD Jones US Patent App. 16/741,827, 2020 | | 2020 |
Phosphorylation-based mirna sensor R Weiss, RD Jones, J Huh US Patent App. 16/528,772, 2020 | | 2020 |
Genetic devices for robust, context-independent control of gene expression levels in mammalian cells RD Jones Massachusetts Institute of Technology, 2020 | | 2020 |