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Simon Sau Yin Law
Simon Sau Yin Law
Postdoctoral Researcher, RIKEN
Verified email at alumni.ubc.ca
Title
Cited by
Cited by
Year
An ectosteric inhibitor of cathepsin K inhibits bone resorption in ovariectomized mice
P Panwar, L Xue, K Søe, K Srivastava, S Law, JM Delaisse, D Brömme
Journal of Bone and Mineral Research 32 (12), 2415-2430, 2017
522017
Polymer-coated carbon nanotube hybrids with functional peptides for gene delivery into plant mitochondria
SSY Law, G Liou, Y Nagai, J Giménez-Dejoz, A Tateishi, K Tsuchiya, ...
Nature communications 13 (1), 2417, 2022
302022
Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib
S Law, PM Andrault, AH Aguda, NT Nguyen, N Kruglyak, GD Brayer, ...
Biochemical Journal 474 (5), 851-864, 2017
282017
Tanshinones that selectively block the collagenase activity of cathepsin K provide a novel class of ectosteric antiresorptive agents for bone
P Panwar, S Law, A Jamroz, P Azizi, D Zhang, M Ciufolini, D Brömme
British journal of pharmacology 175 (6), 902-923, 2018
242018
Affinity crystallography: A new approach to extracting high-affinity enzyme inhibitors from natural extracts
AH Aguda, V Lavallee, P Cheng, TM Bott, LG Meimetis, S Law, ...
Journal of natural products 79 (8), 1962-1970, 2016
232016
A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K
S Law, P Panwar, J Li, AH Aguda, A Jamroz, RVC Guido, D Brömme
PloS one 12 (10), e0186869, 2017
112017
Organelle-targeted gene delivery in plants by nanomaterials
SSY Law, T Miyamoto, K Numata
Chemical Communications 59 (47), 7166-7181, 2023
52023
Cellular internalization mechanism of novel Raman probes designed for plant cells
K Midorikawa, K Tsuchiya, SSY Law, Y Miyagi, T Asai, T Iino, Y Ozeki, ...
RSC Chemical Biology 1 (4), 204-208, 2020
52020
Erratum to: An Ectosteric Inhibitor of Cathepsin K Inhibits Bone Resorption in Ovariectomized Mice: ECTOSTERIC INHIBITOR OF CATK INHIBITS BONE RESORPTION (Journal of Bone and …
P Panwar, L Xue, K Søe, K Srivastava, S Law, JM Delaisse, D Brömme
Journal of Bone and Mineral Research 34 (4), 777-778, 2019
52019
Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening
S Law, X Du, P Panwar, NS Honson, T Pfeifer, M Roberge, D Brömme
Biochemical Journal 476 (3), 499-512, 2019
42019
Deuterium-and Alkyne-Based Bioorthogonal Raman Probes for In Situ Quantitative Metabolic Imaging of Lipids within Plants
SSY Law, M Asanuma, J Shou, Y Ozeki, Y Kodama, K Numata
JACS Au 3 (6), 1604-1614, 2023
32023
Leupeptazin, a highly modified tripeptide isolated from cultures of a Streptomyces sp. inhibits cathepsin K
N Kruglyak, DE Williams, H Chen, S Law, J Kaleta, I Villanueva, ...
Bioorganic & Medicinal Chemistry Letters 27 (6), 1397-1400, 2017
12017
Cross-linking polybutadiene rubber via a thiol-ene reaction with polycysteine as a degradable cross-linker
K Tsuchiya, K Terada, Y Tsuji, SSY Law, H Masunaga, T Katashima, ...
Polymer Journal, 1-10, 2023
2023
Optimal glycan density for interactions between Siglec-8 and sialyl sulfo oligosaccharides
R Naka, SSY Law, A Tateishi, K Numata, M Ohmae
Polymer Journal 55 (12), 1379-1386, 2023
2023
Substrate-specific inhibitors of cathepsin K
S Law, AH Aguda, U Dalwadi, Z Jiang, NT Nguyen, A O'Donoghue, ...
BRITISH JOURNAL OF PHARMACOLOGY 176 (16), 3073-3074, 2019
2019
Allosteric or ectosteric inhibition of cathepsin K by an exosite inhibitor
S Law, D Bromme
JOURNAL OF BONE AND MINERAL RESEARCH 33, 178-178, 2018
2018
Structural insights into inhibitory mechanisms of cathepsin K
SSY Law
University of British Columbia, 2018
2018
Identification of mouse cathepsin K structural elements that regulate its collagenase activity and the potency of odanacatib.
S Law, PM Andrault, AH Aguda, A Yamroz, M Lee, GD Brayer, D Bromme
JOURNAL OF BONE AND MINERAL RESEARCH 32, S276-S276, 2017
2017
Ectosteric inhibitors of cathepsin K prevent bone resorption
P Panwar, K Søe, S Law, JM Delaissé, D Brömme
Journal of Bone and Mineral Research 30 (Suppl. 1), SU0341, 2015
2015
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Articles 1–19