Olaf Groß
Olaf Groß
Institute of Neuropathology, Medical Center – University of Freiburg
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Syk-and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
S LeibundGut-Landmann, O Groß, MJ Robinson, F Osorio, EC Slack, ...
Nature immunology 8 (6), 630-638, 2007
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
O Gross, H Poeck, M Bscheider, C Dostert, N Hannesschläger, S Endres, ...
Nature 459 (7245), 433-436, 2009
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
O Gross, A Gewies, K Finger, M Schäfer, T Sparwasser, C Peschel, ...
Nature 442 (7103), 651-656, 2006
A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections
EO Glocker, A Hennigs, M Nabavi, AA Schäffer, C Woellner, U Salzer, ...
New England Journal of Medicine 361 (18), 1727-1735, 2009
The inflammasome: an integrated view
O Gross, CJ Thomas, G Guarda, J Tschopp
Immunological reviews 243 (1), 136-151, 2011
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation
MJC Jordão, R Sankowski, SM Brendecke, Sagar, G Locatelli, YH Tai, ...
Science 363 (6425), eaat7554, 2019
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ...
Nature immunology 11 (1), 63-69, 2010
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection
MJ Robinson, F Osorio, M Rosas, RP Freitas, E Schweighoffer, O Groß, ...
Journal of Experimental Medicine 206 (9), 2037-2051, 2009
Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1
O Groß, AS Yazdi, CJ Thomas, M Masin, LX Heinz, G Guarda, M Quadroni, ...
Immunity 36 (3), 388-400, 2012
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
JE Vince, WWL Wong, I Gentle, KE Lawlor, R Allam, L O'Reilly, K Mason, ...
Immunity 36 (2), 215-227, 2012
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
C Dostert, G Guarda, JF Romero, P Menu, O Gross, A Tardivel, ML Suva, ...
PloS one 4 (8), e6510, 2009
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria
CJ Groß, R Mishra, KS Schneider, G Médard, J Wettmarshausen, ...
Immunity 45 (4), 761-773, 2016
Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy
K Shahzad, F Bock, W Dong, H Wang, S Kopf, S Kohli, S Ranjan, J Wolter, ...
Kidney international 87 (1), 74-84, 2015
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRγ–Syk–Card9–dependent innate immune activation
K Werninghaus, A Babiak, O Groß, C Hölscher, H Dietrich, EM Agger, ...
Journal of Experimental Medicine 206 (1), 89-97, 2009
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses
M Ritter, O Gross, S Kays, J Ruland, F Nimmerjahn, S Saijo, J Tschopp, ...
Proceedings of the National Academy of Sciences 107 (47), 20459-20464, 2010
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation
M Yabal, N Müller, H Adler, N Knies, CJ Groß, RB Damgaard, ...
Cell reports 7 (6), 1796-1808, 2014
Clostridium difficile toxin–induced inflammation and intestinal injury are mediated by the inflammasome
J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ...
Gastroenterology 139 (2), 542-552. e3, 2010
The inflammasome drives GSDMD-independent secondary pyroptosis and IL-1 release in the absence of caspase-1 protease activity
KS Schneider, CJ Groß, RF Dreier, BS Saller, R Mishra, O Gorka, R Heilig, ...
Cell reports 21 (13), 3846-3859, 2017
Immune modulatory effects of oncogenic KRAS in cancer
S Hamarsheh, O Groß, T Brummer, R Zeiser
Nature communications 11 (1), 5439, 2020
The adaptor molecule CARD9 is essential for tuberculosis control
A Dorhoi, C Desel, V Yeremeev, L Pradl, V Brinkmann, HJ Mollenkopf, ...
Journal of Experimental Medicine 207 (4), 777-792, 2010
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