p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs CJ Chang, CH Chao, W Xia, JY Yang, Y Xiong, CW Li, WH Yu, ... Nature cell biology 13 (3), 317-323, 2011 | 876 | 2011 |
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway DF Lee, HP Kuo, CT Chen, JM Hsu, CK Chou, Y Wei, HL Sun, LY Li, ... Cell 130 (3), 440-455, 2007 | 813 | 2007 |
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3 TL Cha, BP Zhou, W Xia, Y Wu, CC Yang, CT Chen, B Ping, AP Otte, ... science 310 (5746), 306-310, 2005 | 617 | 2005 |
EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling CJ Chang, JY Yang, W Xia, CT Chen, X Xie, CH Chao, WA Woodward, ... Cancer cell 19 (1), 86-100, 2011 | 469 | 2011 |
Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization Q Ding, X He, JM Hsu, W Xia, CT Chen, LY Li, DF Lee, JC Liu, Q Zhong, ... Molecular and cellular biology 27 (11), 4006-4017, 2007 | 467 | 2007 |
KEAP1 E3 ligase-mediated downregulation of NF-κB signaling by targeting IKKβ DF Lee, HP Kuo, M Liu, CK Chou, W Xia, Y Du, J Shen, CT Chen, L Huo, ... Molecular cell 36 (1), 131-140, 2009 | 423 | 2009 |
Tyrosine phosphorylation controls PCNA function through protein stability SC Wang, Y Nakajima, YL Yu, W Xia, CT Chen, CC Yang, EW McIntush, ... Nature cell biology 8 (12), 1359-1368, 2006 | 372 | 2006 |
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion JM Hsu, W Xia, YH Hsu, LC Chan, WH Yu, JH Cha, CT Chen, HW Liao, ... Nature communications 9 (1), 1908, 2018 | 338 | 2018 |
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation JM Hsu, CT Chen, CK Chou, HP Kuo, LY Li, CY Lin, HJ Lee, YN Wang, ... Nature cell biology 13 (2), 174-181, 2011 | 258 | 2011 |
Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3β activity and associates with poor prognosis in human breast cancer Q Ding, X He, W Xia, JM Hsu, CT Chen, LY Li, DF Lee, JY Yang, X Xie, ... Cancer research 67 (10), 4564-4571, 2007 | 246 | 2007 |
Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth TL Cha, L Qiu, CT Chen, Y Wen, MC Hung Cancer research 65 (6), 2287-2295, 2005 | 233 | 2005 |
Blocking c-Met–mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors Y Du, H Yamaguchi, Y Wei, JL Hsu, HL Wang, YH Hsu, WC Lin, WH Yu, ... Nature medicine 22 (2), 194-201, 2016 | 228 | 2016 |
Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation K Liang, FJ Esteva, C Albarracin, K Stemke-Hale, Y Lu, G Bianchini, ... Cancer cell 18 (5), 423-435, 2010 | 171 | 2010 |
ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway HP Kuo, DF Lee, CT Chen, M Liu, CK Chou, HJ Lee, Y Du, X Xie, Y Wei, ... Science signaling 3 (108), ra9-ra9, 2010 | 120 | 2010 |
Caspase-independent cell death is involved in the negative effect of egf receptor inhibitors on cisplatin in non–small cell lung cancer cells H Yamaguchi, JL Hsu, CT Chen, YN Wang, MC Hsu, SS Chang, Y Du, ... Clinical cancer research 19 (4), 845-854, 2013 | 116 | 2013 |
IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression M Liu, DF Lee, CT Chen, CJ Yen, LY Li, HJ Lee, CJ Chang, WC Chang, ... Molecular cell 45 (2), 171-184, 2012 | 114 | 2012 |
IKKβ suppression of TSC1 function links the mTOR pathway with insulin resistance DF Lee, HP Kuo, CT Chen, Y Wei, CK Chou, JY Hung, CJ Yen, MC Hung International journal of molecular medicine 22 (5), 633-638, 2008 | 102 | 2008 |
The role of PIM1 in the ibrutinib-resistant ABC subtype of diffuse large B-cell lymphoma HP Kuo, SA Ezell, S Hsieh, KJ Schweighofer, LWK Cheung, S Wu, ... American journal of cancer research 6 (11), 2489, 2016 | 76 | 2016 |
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma CJ Yen, JG Izzo, DF Lee, S Guha, Y Wei, TT Wu, CT Chen, HP Kuo, ... Cancer research 68 (8), 2632-2640, 2008 | 74 | 2008 |
Angiogenin/ribonuclease 5 is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer YN Wang, HH Lee, CK Chou, WH Yang, Y Wei, CT Chen, J Yao, JL Hsu, ... Cancer Cell 33 (4), 752-769. e8, 2018 | 70 | 2018 |