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An Xu
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GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability
WL Hu, L Jin, AN Xu, YF Wang, RF Thorne, XD Zhang, M Wu
Nature cell biology 20 (4), 492-502, 2018
2622018
Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism
H Kim, S Yoo, R Zhou, A Xu, JM Bernitz, Y Yuan, AM Gomes, MG Daniel, ...
Proceedings of the National Academy of Sciences 115 (47), E11128-E11137, 2018
522018
Li–Fraumeni syndrome disease model: a platform to develop precision cancer therapy targeting oncogenic p53
R Zhou, A Xu, J Gingold, LC Strong, R Zhao, DF Lee
Trends in pharmacological sciences 38 (10), 908-927, 2017
492017
BECN1s, a short splice variant of BECN1, functions in mitophagy
B Cheng, A Xu, M Qiao, Q Wu, W Wang, Y Mei, M Wu
Autophagy 11 (11), 2048-2056, 2015
282015
Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies
J Tu, Z Huo, Y Yu, D Zhu, A Xu, MF Huang, R Hu, R Wang, JA Gingold, ...
Proceedings of the National Academy of Sciences 119 (16), e2117857119, 2022
162022
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome
BE Jewell, A Xu, D Zhu, MF Huang, L Lu, M Liu, EL Underwood, JH Park, ...
PLoS Genetics 17 (12), e1009971, 2021
132021
Modeling osteosarcoma using Li-fraumeni syndrome patient-derived induced pluripotent stem cells
R Zhou, A Xu, J Tu, M Liu, JA Gingold, R Zhao, DF Lee
JoVE (Journal of Visualized Experiments), e57664, 2018
132018
Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase
J Tu, Z Huo, M Liu, D Wang, A Xu, R Zhou, D Zhu, J Gingold, J Shen, ...
Stem cell research 28, 29-32, 2018
132018
RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III–dependent transcription
F Wang, K Zhao, S Yu, A Xu, W Han, Y Mei
Journal of Biological Chemistry 294 (1), 130-141, 2019
122019
Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing
Z Huo, J Tu, A Xu, Y Li, D Wang, M Liu, R Zhou, D Zhu, Y Lin, JA Gingold, ...
Stem cell research 34, 101360, 2019
122019
LncRNA H19 suppresses osteosarcomagenesis by regulating snoRNAs and DNA repair protein complexes
DF Lee, A Xu, MF Huang, D Zhu, JA Gingold, B Chang, D Wang, CC Lai, ...
Frontiers in Genetics 11, 1773, 2020
112020
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing
A Xu, R Zhou, J Tu, Z Huo, D Zhu, D Wang, JA Gingold, H Mata, PH Rao, ...
Stem cell research 29, 215-219, 2018
102018
A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing
R Zhou, A Xu, D Wang, D Zhu, H Mata, Z Huo, J Tu, M Liu, AMT Mohamed, ...
Stem cell research 27, 131-135, 2018
102018
Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1
PS Huang, MH Wen, X Xie, A Xu, DF Lee, TY Chen
Stem cell research 54, 102415, 2021
52021
Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
JH Choe, T Kawase, A Xu, A Guzman, AZ Obradovic, AM Low-Calle, ...
Cancer Discovery, OF1-OF24, 2023
42023
Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation
A Xu, M Liu, MF Huang, Y Zhang, R Hu, JA Gingold, Y Liu, D Zhu, ...
Nature Communications 14 (1), 1694, 2023
42023
Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation
BE Jewell, M Liu, L Lu, R Zhou, J Tu, D Zhu, Z Huo, A Xu, D Wang, H Mata, ...
Stem cell research 33, 36-40, 2018
32018
Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
D Chachad, LR Patel, CV Recio, R Pourebrahim, EM Whitley, W Wang, ...
Cancer Research, CAN-22-3464, 2023
22023
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