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Patrizia Porazzi
Patrizia Porazzi
Senior Research Investigator at Center for Immunotherapies @UPenn
Verified email at pennmedicine.upenn.edu
Title
Cited by
Cited by
Year
Thyroid gland development and function in the zebrafish model
P Porazzi, D Calebiro, F Benato, N Tiso, L Persani
Molecular and cellular endocrinology 312 (1-2), 14-23, 2009
2092009
Wnt activation promotes neuronal differentiation of glioblastoma
E Rampazzo, L Persano, F Pistollato, E Moro, C Frasson, P Porazzi, ...
Cell death & disease 4 (2), e500-e500, 2013
1282013
Generation and application of signaling pathway reporter lines in zebrafish
E Moro, A Vettori, P Porazzi, M Schiavone, E Rampazzo, A Casari, O Ek, ...
Molecular genetics and genomics 288, 231-242, 2013
782013
JAG1 loss-of-function variations as a novel predisposing event in the pathogenesis of congenital thyroid defects
T De Filippis, F Marelli, G Nebbia, P Porazzi, S Corbetta, L Fugazzola, ...
The Journal of Clinical Endocrinology & Metabolism 101 (3), 861-870, 2016
642016
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice
G Casella, J Rasouli, A Boehm, W Zhang, D Xiao, LLW Ishikawa, ...
Science translational medicine 12 (568), eaba0599, 2020
592020
Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and-independent effects by CDK6-specific PROTACs
M De Dominici, P Porazzi, Y Xiao, A Chao, HY Tang, G Kumar, P Fortina, ...
Blood, The Journal of the American Society of Hematology 135 (18), 1560-1573, 2020
582020
Disruptions of global and JAGGED1-mediated notch signaling affect thyroid morphogenesis in the zebrafish
P Porazzi, F Marelli, F Benato, T de Filippis, D Calebiro, F Argenton, ...
Endocrinology 153 (11), 5645-5658, 2012
532012
Selective modulation of protein kinase AI and II reveals distinct roles in thyroid cell gene expression and growth
D Calebiro, T de Filippis, S Lucchi, F Martinez, P Porazzi, R Trivellato, ...
Molecular endocrinology 20 (12), 3196-3211, 2006
482006
Expanding the genotypic and phenotypic spectrum in a diverse cohort of 104 individuals with Wiedemann‐Steiner syndrome
SE Sheppard, IM Campbell, MH Harr, N Gold, D Li, HT Bjornsson, ...
American Journal of Medical Genetics Part A 185 (6), 1649-1665, 2021
412021
Increased risk for non-autoimmune hypothyroidism in young patients with congenital heart defects
E Passeri, M Frigerio, T De Filippis, R Valaperta, P Capelli, E Costa, ...
The Journal of Clinical Endocrinology & Metabolism 96 (7), E1115-E1119, 2011
392011
Structure of nascent chromatin is essential for hematopoietic lineage specification
S Petruk, SA Mariani, M De Dominici, P Porazzi, V Minieri, J Cai, ...
Cell reports 19 (2), 295-306, 2017
352017
Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia
KA Urtishak, LS Wang, B Culjkovic-Kraljacic, JW Davenport, P Porazzi, ...
Oncogene 38 (13), 2241-2262, 2019
342019
Absence of primary hypothyroidism and goiter in Slc26a4 (-/-) mice fed on a low iodine diet
D Calebiro, P Porazzi, M Bonomi, S Lisi, A Grindati, D De Nittis, ...
Journal of endocrinological investigation 34, 593-598, 2011
322011
Targeting STAT5 or STAT5-regulated pathways suppresses leukemogenesis of Ph+ acute lymphoblastic leukemia
V Minieri, M De Dominici, P Porazzi, SA Mariani, O Spinelli, A Rambaldi, ...
Cancer research 78 (20), 5793-5807, 2018
272018
Targeting CDK6 and BCL2 exploits the “MYB addiction” of Ph+ acute lymphoblastic leukemia
M De Dominici, P Porazzi, AR Soliera, SA Mariani, S Addya, P Fortina, ...
Cancer research 78 (4), 1097-1109, 2018
252018
Modulation of BCL-2 in both T cells and tumor cells to enhance chimeric antigen receptor T-cell immunotherapy against cancer
YG Lee, P Guruprasad, G Ghilardi, R Pajarillo, CT Sauter, R Patel, ...
Cancer discovery 12 (10), 2372-2391, 2022
242022
Targeting chemotherapy to decondensed H3K27me3-marked chromatin of AML cells enhances leukemia suppression
P Porazzi, S Petruk, L Pagliaroli, M De Dominici, D Deming, MV Puccetti, ...
Cancer research 82 (3), 458-471, 2022
182022
Mechanisms of resistance to chimeric antigen receptor-T cells in haematological Malignancies
M Ruella, F Korell, P Porazzi, MV Maus
Nature Reviews Drug Discovery 22 (12), 976-995, 2023
162023
Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related …
L Pagliaroli, P Porazzi, AT Curtis, C Scopa, HMM Mikkers, C Freund, ...
Nature Communications 12 (1), 6469, 2021
162021
IFN-β acts on monocytes to ameliorate CNS autoimmunity by inhibiting proinflammatory cross-talk between monocytes and Th cells
J Rasouli, G Casella, LLW Ishikawa, R Thome, A Boehm, A Ertel, ...
Frontiers in immunology 12, 679498, 2021
122021
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