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Janet Brownlees
Janet Brownlees
Director
Verified email at merck.com
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Cited by
Year
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ...
Human molecular genetics 16 (22), 2720-2728, 2007
4532007
Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments
S Ackerley, P Thornhill, AJ Grierson, J Brownlees, BH Anderton, PN Leigh, ...
The Journal of cell biology 161 (3), 489-495, 2003
2422003
Charcot–Marie–Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
J Brownlees, S Ackerley, AJ Grierson, NJO Jacobsen, K Shea, ...
Human molecular genetics 11 (23), 2837-2844, 2002
2412002
Glutamate slows axonal transport of neurofilaments in transfected neurons
S Ackerley, AJ Grierson, J Brownlees, P Thornhill, BH Anderton, PN Leigh, ...
The Journal of cell biology 150 (1), 165-176, 2000
2162000
Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3β transgenes
J Brownlees, NG Irving, JP Brion, BJM Gibb, U Wagner, J Woodgett, ...
Neuroreport 8 (15), 3251-3255, 1997
1781997
Peptidases, peptides, and the mammalian blood–brain barrier
J Brownlees, CH Williams
Journal of neurochemistry 60 (3), 793-803, 1993
1671993
Phosphorylation of thr668 in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress‐activated protein kinase 1b (Jun N‐terminalá…
CL Standen, J Brownlees, AJ Grierson, S Kesavapany, KF Lau, ...
Journal of neurochemistry 76 (1), 316-320, 2001
1482001
p38α stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis
S Ackerley, AJ Grierson, S Banner, MS Perkinton, J Brownlees, HL Byers, ...
Molecular and Cellular Neuroscience 26 (2), 354-364, 2004
1462004
Axonal transport of neurofilaments in normal and disease states
CCJ Miller, S Ackerley, J Brownlees, AJ Grierson, NJO Jacobsen, ...
Cellular and Molecular Life Sciences CMLS 59 (2), 323-330, 2002
1232002
p35/cdk5 binds and phosphorylates β‐catenin and regulates β‐catenin/presenilin‐1 interaction
S Kesavapany, KF Lau, DM McLoughlin, J Brownlees, S Ackerley, ...
European Journal of Neuroscience 13 (2), 241-247, 2001
1232001
Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3
J Brownlees, A Yates, NP Bajaj, D Davis, BH Anderton, PN Leigh, ...
Journal of Cell Science 113 (3), 401-407, 2000
1212000
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth
EL Tudor, MS Perkinton, A Schmidt, S Ackerley, J Brownlees, ...
Journal of biological chemistry 280 (41), 34735-34740, 2005
982005
Mint2/X11‐like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease
DM McLoughlin, NG Irving, J Brownlees, JP Brion, K Leroy, CCJ Miller
European journal of neuroscience 11 (6), 1988-1994, 1999
981999
Overexpression of the mouse dishevelled-1 protein inhibits GSK-3β-mediated phosphorylation of tau in transfected mammalian cells
U Wagner, J Brownlees, NG Irving, FR Lucas, PC Salinas, CCJ Miller
FEBS letters 411 (2-3), 369-372, 1997
631997
Neuropathological abnormalities in transgenic mice harbouring a phosphorylation mutant neurofilament transgene
BJM Gibb, JP Brion, J Brownlees, BH Anderton, CCJ Miller
Journal of neurochemistry 70 (2), 492-500, 1998
571998
Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X
G Antonios, H Borgers, BC Richard, A Brau▀, J Mei▀ner, S Weggen, ...
Scientific reports 5 (1), 1-14, 2015
482015
Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses
E Redondo-Castro, D Faust, S Fox, AG Baldwin, S Osborne, MJ Haley, ...
Scientific reports 8 (1), 1-11, 2018
252018
Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF
TM Chapman, KJ Gillen, C Wallace, MT Lee, P Bakrania, P Khurana, ...
Bioorganic & Medicinal Chemistry Letters 25 (19), 4097-4103, 2015
252015
Gigaxonin is associated with the Golgi and dimerises via its BTB domain
VC Cullen, J Brownlees, S Banner, BH Anderton, PN Leigh, CE Shaw, ...
Neuroreport 15 (5), 873-876, 2004
212004
N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1–XPF
TM Chapman, C Wallace, KJ Gillen, P Bakrania, P Khurana, PJ Coombs, ...
Bioorganic & medicinal chemistry letters 25 (19), 4104-4108, 2015
202015
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