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Romila Mascarenhas
Romila Mascarenhas
Verified email at umich.edu
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Cited by
Cited by
Year
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator …
JI Juncosa, K Takaya, HV Le, MJ Moschitto, PM Weerawarna, ...
Journal of the American Chemical Society 140 (6), 2151-2164, 2018
702018
Structural and biochemical characterization of AidC, a quorum-quenching lactonase with atypical selectivity
R Mascarenhas, PW Thomas, CX Wu, BP Nocek, QQ Hoang, D Liu, ...
Biochemistry 54 (28), 4342-4353, 2015
232015
An Interprotein Co–S Coordination Complex in the B12-Trafficking Pathway
Z Li, R Mascarenhas, UT Twahir, A Kallon, A Deb, M Yaw, J Penner-Hahn, ...
Journal of the American Chemical Society 142 (38), 16334-16345, 2020
212020
Selective targeting by a mechanism-based inactivator against pyridoxal 5′-phosphate-dependent enzymes: Mechanisms of inactivation and alternative turnover
R Mascarenhas, HV Le, KD Clevenger, HJ Lehrer, D Ringe, NL Kelleher, ...
Biochemistry 56 (37), 4951-4961, 2017
202017
The human B12 trafficking protein CblC processes nitrocobalamin
R Mascarenhas, Z Li, C Gherasim, M Ruetz, R Banerjee
Journal of Biological Chemistry 295 (28), 9630-9640, 2020
192020
Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12
R Mascarenhas, M Ruetz, L McDevitt, M Koutmos, R Banerjee
Proceedings of the National Academy of Sciences 117 (48), 30412-30422, 2020
162020
Human B12-dependent enzymes: Methionine synthase and Methylmalonyl-CoA mutase
R Mascarenhas, H Gouda, M Ruetz, R Banerjee
Methods in enzymology 668, 309-326, 2022
112022
Structural analysis reveals a pyruvate-binding activator site in the Agrobacterium tumefaciens ADP–glucose pyrophosphorylase
BL Hill, R Mascarenhas, HP Patel, MDA Diez, R Wu, AA Iglesias, D Liu, ...
Journal of Biological Chemistry 294 (4), 1338-1348, 2019
102019
Substrate trapping in the siderophore tailoring enzyme PvdQ
KD Clevenger, R Mascarenhas, D Catlin, R Wu, NL Kelleher, EJ Drake, ...
ACS chemical biology 12 (3), 643-647, 2017
92017
On the simultaneous activation of Agrobacterium tumefaciens ADP-glucose pyrophosphorylase by pyruvate and fructose 6-phosphate
MDA Diez, CM Figueroa, MC Esper, R Mascarenhas, MC Aleanzi, D Liu, ...
Biochimie 171, 23-30, 2020
52020
Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation
JV Roman, R Mascarenhas, K Ceric, DP Ballou, R Banerjee
Journal of Biological Chemistry 299 (12), 2023
32023
Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B12 repair
H Gouda, R Mascarenhas, M Ruetz, M Yaw, R Banerjee
Proceedings of the National Academy of Sciences 120 (11), e2220677120, 2023
32023
Cyclobutanone inhibitor of cobalt-functionalized metallo-γ-lactonase AiiA with cyclobutanone ring opening in the active site
CT Reidl, R Mascarenhas, TSH Mohammad, MR Lutz Jr, PW Thomas, ...
ACS omega 6 (21), 13567-13578, 2021
32021
Patient mutations in human ATP: cob (I) alamin adenosyltransferase differentially affect its catalytic versus chaperone functions
H Gouda, R Mascarenhas, S Pillay, M Ruetz, M Koutmos, R Banerjee
Journal of Biological Chemistry 297 (6), 2021
22021
Cobalt–Sulfur Coordination Chemistry Drives B12 Loading onto Methionine Synthase
R Mascarenhas, A Guha, Z Li, M Ruetz, S An, J Seravalli, R Banerjee
Journal of the American Chemical Society 145 (45), 24678-24689, 2023
12023
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair
R Mascarenhas, M Ruetz, H Gouda, N Heitman, M Yaw, R Banerjee
Nature Communications 14 (1), 4332, 2023
12023
The impact of patient mutations on coenzyme B12 loading and repair
M Ruetz, R Mascarenhas, H Gouda, N Heitman, R Banerjee
Journal of Biological Chemistry 299 (3), S336, 2023
2023
Human Methionine B12-dependent synthase enzymes: and Methylmalonyl-CoA mutase
R Mascarenhas, H Gouda, M Ruetz, R Banerjee
Coenzyme B12 Enzymes Part A, 309, 2022
2022
Reply to Sysel et al.: Comment on the importance of using nitric oxide gas in the synthesis of nitrosylcobalamin and ICH-validated methods to assess purity and stability
R Mascarenhas, Z Li, C Gherasim, M Ruetz, R Banerjee
The Journal of Biological Chemistry 295 (43), 14790, 2020
2020
Interprotein Co–S Coordination Complex in the B₁₂-Trafficking Pathway
Z Li, R Mascarenhas, UT Twahir, A Kallon, A Deb, M Yaw, J Penner-Hahn, ...
2020
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