CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy SP Sardi, J Clarke, C Kinnecom, TJ Tamsett, L Li, LM Stanek, MA Passini, ... Proceedings of the National Academy of Sciences 108 (29), 12101-12106, 2011 | 339 | 2011 |
Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies SP Sardi, J Clarke, C Viel, M Chan, TJ Tamsett, CM Treleaven, J Bu, ... Proceedings of the National Academy of Sciences 110 (9), 3537-3542, 2013 | 285 | 2013 |
Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis JC Dodge, CM Treleaven, J Pacheco, S Cooper, C Bao, M Abraham, ... Proceedings of the National Academy of Sciences 112 (26), 8100-8105, 2015 | 129 | 2015 |
Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis JC Dodge, CM Treleaven, JA Fidler, TJ Tamsett, C Bao, M Searles, ... Proceedings of the National Academy of Sciences 110 (26), 10812-10817, 2013 | 116 | 2013 |
NAD+ activates KNa channels in dorsal root ganglion neurons TJ Tamsett, KE Picchione, A Bhattacharjee Journal of Neuroscience 29 (16), 5127-5134, 2009 | 105 | 2009 |
Gene transfer to the CNS is efficacious in immune-primed mice harboring physiologically relevant titers of anti-AAV antibodies CM Treleaven, TJ Tamsett, J Bu, JA Fidler, SP Sardi, GD Hurlbut, ... Molecular Therapy 20 (9), 1713-1723, 2012 | 39 | 2012 |
Disease progression in a mouse model of amyotrophic lateral sclerosis: the influence of chronic stress and corticosterone JA Fidler, CM Treleaven, A Frakes, TJ Tamsett, M McCrate, SH Cheng, ... The FASEB Journal 25 (12), 4369, 2011 | 39 | 2011 |
Distribution of acid sphingomyelinase in rodent and non-human primate brain after intracerebroventricular infusion RJ Ziegler, EA Salegio, JC Dodge, J Bringas, CM Treleaven, SD Bercury, ... Experimental neurology 231 (2), 261-271, 2011 | 37 | 2011 |
Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of … JC Dodge, TJ Tamsett, CM Treleaven, TV Taksir, P Piepenhagen, ... Alzheimer's Research & Therapy 14 (1), 19, 2022 | 7 | 2022 |
Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery CM Treleaven, T Tamsett, JA Fidler, TV Taksir, SH Cheng, ... Plos one 6 (1), e16313, 2011 | 5 | 2011 |
Structure–Activity Relationship Evaluation of Wasp Toxin β-PMTX Leads to Analogs with Superior Activity for Human Neuronal Sodium Channels CE Garrison, W Guan, M Kato, T Tamsett, T Patel, Y Sun, TP Pathak ACS Medicinal Chemistry Letters 11 (3), 353-357, 2019 | 2 | 2019 |
Sodium activated potassium channels (K (Na)) are modulated by nicotinamide adenine dinucleotide (NAD+) in adult dorsal root ganglion (DRG) neurons TJ Tamsett State University of New York at Buffalo, 2008 | 1 | 2008 |
SAR evaluation of wasp toxin-PMTX leads to analogs with superior efficacy for human neuronal sodium channels C Garrison, W Guan, M Kato, T Tamsett, T Patel, Y Sun, T Pathak ACS Medicinal Chemistry Letters, 2019 | | 2019 |