Mark Donowitz
Mark Donowitz
Professor of Medicine and Physiology, Johns Hopkins University School of Medicine
Verified email at
Cited by
Cited by
The burden of selected digestive diseases in the United States
RS Sandler, JE Everhart, M Donowitz, E Adams, K Cronin, C Goodman, ...
Gastroenterology 122 (5), 1500-1511, 2002
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
SJ Grille, A Bellacosa, J Upson, AJ Klein-Szanto, F Van Roy, W Lee-Kwon, ...
Cancer research 63 (9), 2172-2178, 2003
TAZ: a novel transcriptional co‐activator regulated by interactions with 14‐3‐3 and PDZ domain proteins
F Kanai, PA Marignani, D Sarbassova, R Yagi, RA Hall, M Donowitz, ...
The EMBO journal, 2000
Evolutionary origins of eukaryotic sodium/proton exchangers
CL Brett, M Donowitz, R Rao
American Journal of Physiology-Cell Physiology 288 (2), C223-C239, 2005
cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein
CHC Yun, S Oh, M Zizak, D Steplock, S Tsao, CM Tse, EJ Weinman, ...
Proceedings of the National Academy of Sciences 94 (7), 3010-3015, 1997
NC Zachos, M Tse, M Donowitz
Annu. Rev. Physiol. 67, 411-443, 2005
Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3).
CM Tse, SR Brant, MS Walker, J Pouyssegur, M Donowitz
Journal of Biological Chemistry 267 (13), 9340-9346, 1992
A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions
G Noel, NW Baetz, JF Staab, M Donowitz, O Kovbasnjuk, MF Pasetti, ...
Scientific reports 7 (1), 45270, 2017
Human intestinal enteroids: a new model to study human rotavirus infection, host restriction, and pathophysiology
K Saxena, SE Blutt, K Ettayebi, XL Zeng, JR Broughman, SE Crawford, ...
Journal of virology 90 (1), 43-56, 2016
NHE2 and NHE3 are human and rabbit intestinal brush-border proteins
WA Hoogerwerf, SC Tsao, O Devuyst, SA Levine, CH Yun, JW Yip, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 270 (1 …, 1996
Na+/H+ exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling
MJ Mahon, M Donowitz, CC Yun, GV Segre
Nature 417 (6891), 858-861, 2002
Mammalian Na+/H+ exchanger gene family: structure and function studies
CH Yun, CM Tse, SK Nath, SA Levine, SR Brant, M Donowitz
American Journal of Physiology-Gastrointestinal and Liver Physiology 269 (1 …, 1995
Akt as a mediator of cell death
HR Luo, H Hattori, MA Hossain, L Hester, Y Huang, W Lee-Kwon, ...
Proceedings of the National Academy of Sciences 100 (20), 11712-11717, 2003
SLC9/NHE gene family, a plasma membrane and organellar family of Na+/H+ exchangers
M Donowitz, CM Tse, D Fuster
Molecular aspects of medicine 34 (2-3), 236-251, 2013
Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and pathophysiology
NC Zachos, O Kovbasnjuk, J Foulke-Abel, J In, SE Blutt, HR De Jonge, ...
Journal of Biological Chemistry 291 (8), 3759-3766, 2016
Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line.
SA Levine, MH Montrose, CM Tse, M Donowitz
Journal of Biological Chemistry 268 (34), 25527-25535, 1993
Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2)
CM Tse, SA Levine, CH Yun, MH Montrose, PJ Little, J Pouyssegur, ...
Journal of Biological Chemistry 268 (16), 11917-11924, 1993
NaCl uptake by the branchial epithelium in freshwater teleost fish: an immunological approach to ion-transport protein localization
JM Wilson, P Laurent, BL Tufts, DJ Benos, M Donowitz, AW Vogl, ...
Journal of Experimental Biology 203 (15), 2279-2296, 2000
Squalamine Inhibits Angiogenesis and Solid Tumor Growth in Vivo and Perturbs Embryonic Vasculature
AK Sills Jr, JI Williams, BM Tyler, DS Epstein, EP Sipos, JD Davis, ...
Cancer Research 58 (13), 2784-2792, 1998
Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle
L Vernetti, A Gough, N Baetz, S Blutt, JR Broughman, JA Brown, ...
Scientific reports 7 (1), 42296, 2017
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