Henry Brem
Henry Brem
Harvey Cushing Professor, Chairman Dept of Neurosurgery, Johns Hopkins School of Medicine
Verified email at - Homepage
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Detection of circulating tumor DNA in early-and late-stage human malignancies
C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ...
Science translational medicine 6 (224), 224ra24-224ra24, 2014
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
H Brem, S Piantadosi, PC Burger, M Walker, R Selker, NA Vick, K Black, ...
The Lancet 345 (8956), 1008-1012, 1995
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
SGM Piccirillo, BA Reynolds, N Zanetti, G Lamorte, E Binda, G Broggi, ...
Nature 444 (7120), 761-765, 2006
Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
J Zeng, AP See, J Phallen, CM Jackson, Z Belcaid, J Ruzevick, N Durham, ...
International Journal of Radiation Oncology* Biology* Physics 86 (2), 343-349, 2013
Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project
ER Laws, IF Parney, W Huang, F Anderson, AM Morris, A Asher, ...
Journal of neurosurgery 99 (3), 467-473, 2003
Independent association of extent of resection with survival in patients with malignant brain astrocytoma
MJ McGirt, KL Chaichana, M Gathinji, FJ Attenello, K Than, A Olivi, ...
Journal of neurosurgery 110 (1), 156-162, 2009
Polylactic acid (PLA) controlled delivery carriers for biomedical applications
B Tyler, D Gullotti, A Mangraviti, T Utsuki, H Brem
Advanced drug delivery reviews 107, 163-175, 2016
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas
H Brem, MS Mahaley, NA Vick, KL Black, SC Schold, PC Burger, ...
Journal of neurosurgery 74 (3), 441-446, 1991
Multi-pulse drug delivery from a resorbable polymeric microchip device
ACR Grayson, IS Choi, BM Tyler, PP Wang, H Brem, MJ Cima, R Langer
Nature materials 2 (11), 767-772, 2003
Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas
MJ McGirt, KL Chaichana, FJ Attenello, JD Weingart, K Than, PC Burger, ...
Neurosurgery 63 (4), 700-708, 2008
Inhibition of tumor angiogenesis mediated by cartilage.
H Brem, J Folkman
The Journal of experimental medicine 141 (2), 427-439, 1975
Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma
KL Chaichana, I Jusue-Torres, R Navarro-Ramirez, SM Raza, ...
Neuro-oncology 16 (1), 113-122, 2014
Paclitaxel: a review of adverse toxicities and novel delivery strategies
NI Marupudi, JE Han, KW Li, VM Renard, BM Tyler, H Brem
Expert opinion on drug safety 6 (5), 609-621, 2007
Isolations of a cartilage factor that inhibits tumor neovascularization
R Langer, H Brem, K Falterman, M Klein, J Folkman
Science 193 (4247), 70-72, 1976
Patterns of care for adults with newly diagnosed malignant glioma
SM Chang, IF Parney, W Huang, FA Anderson, AL Asher, M Bernstein, ...
Jama 293 (5), 557-564, 2005
Controlled local delivery of chemotherapeutic agents for treating solid tumors
H Brem, RS Langer, AJ Domb
US Patent 5,626,862, 1997
Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease
JE Conway, D Chou, RE Clatterbuck, H Brem, DM Long, D Rigamonti
Neurosurgery 48 (1), 55-63, 2001
Advancing the field of drug delivery: taking aim at cancer
MA Moses, H Brem, R Langer
Cancer cell 4 (5), 337-341, 2003
Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophosphamide, and paclitaxel from a biodegradable polymer implant in the monkey brain
LK Fung, MG Ewend, A Sills, EP Sipos, R Thompson, M Watts, ...
Cancer research 58 (4), 672-684, 1998
Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord
Y Wang, S Springer, M Zhang, KW McMahon, I Kinde, L Dobbyn, J Ptak, ...
Proceedings of the National Academy of Sciences 112 (31), 9704-9709, 2015
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