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Dennis Discher
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Year
Matrix elasticity directs stem cell lineage specification
AJ Engler, S Sen, HL Sweeney, DE Discher
Cell 126 (4), 677-689, 2006
143172006
Tissue cells feel and respond to the stiffness of their substrate
DE Discher, P Janmey, Y Wang
Science 310 (5751), 1139-1143, 2005
67972005
Polymer vesicles
DE Discher, A Eisenberg
Science 297 (5583), 967-973, 2002
40172002
Polymersomes: tough vesicles made from diblock copolymers
BM Discher, YY Won, DS Ege, JCM Lee, FS Bates, DE Discher, ...
Science 284 (5417), 1143-1146, 1999
3449*1999
Growth factors, matrices, and forces combine and control stem cells
DE Discher, DJ Mooney, PW Zandstra
Science 324 (5935), 1673-1677, 2009
28502009
Shape effects of filaments versus spherical particles in flow and drug delivery
YAN Geng, P Dalhaimer, S Cai, R Tsai, M Tewari, T Minko, DE Discher
Nature nanotechnology 2 (4), 249-255, 2007
26842007
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments
AJ Engler, MA Griffin, S Sen, CG Bonnemann, HL Sweeney, DE Discher
The Journal of cell biology 166 (6), 877-887, 2004
19312004
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ...
Science 341 (6149), 1240104, 2013
17212013
Substrate compliance versus ligand density in cell on gel responses
A Engler, L Bacakova, C Newman, A Hategan, M Griffin, D Discher
Biophysical journal 86 (1), 617-628, 2004
13632004
Bio-inspired, bioengineered and biomimetic drug delivery carriers
JW Yoo, DJ Irvine, DE Discher, S Mitragotri
Nature reviews Drug discovery 10 (7), 521-535, 2011
11522011
Mesenchymal stem cell perspective: cell biology to clinical progress
MF Pittenger, DE Discher, BM Péault, DG Phinney, JM Hare, AI Caplan
NPJ Regenerative medicine 4 (1), 22, 2019
9592019
Mitotic progression following DNA damage enables pattern recognition within micronuclei
SM Harding, JL Benci, J Irianto, DE Discher, AJ Minn, RA Greenberg
Nature 548 (7668), 466-470, 2017
9572017
Minimal" Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles
PL Rodriguez, T Harada, DA Christian, DA Pantano, RK Tsai, DE Discher
Science 339 (6122), 971-975, 2013
9552013
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
AJ Engler, C Carag-Krieger, CP Johnson, M Raab, HY Tang, ...
Journal of cell science 121 (22), 3794-3802, 2008
9312008
Physical plasticity of the nucleus in stem cell differentiation
JD Pajerowski, KN Dahl, FL Zhong, PJ Sammak, DE Discher
Proceedings of the National Academy of Sciences 104 (40), 15619-15624, 2007
8822007
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance
MF Berry, AJ Engler, YJ Woo, TJ Pirolli, LT Bish, V Jayasankar, KJ Morine, ...
American Journal of Physiology-Heart and Circulatory Physiology 290 (6 …, 2006
8572006
Self-porating polymersomes of PEG–PLA and PEG–PCL: hydrolysis-triggered controlled release vesicles
F Ahmed, DE Discher
Journal of controlled release 96 (1), 37-53, 2004
7652004
Molecular weight dependence of polymersome membrane structure, elasticity, and stability
H Bermudez, AK Brannan, DA Hammer, FS Bates, DE Discher
Macromolecules 35 (21), 8203-8208, 2002
6112002
Polymer vesicles in vivo: correlations with PEG molecular weight
PJ Photos, L Bacakova, B Discher, FS Bates, DE Discher
Journal of Controlled Release 90 (3), 323-334, 2003
6062003
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug
F Ahmed, RI Pakunlu, A Brannan, F Bates, T Minko, DE Discher
Journal of Controlled Release 116 (2), 150-158, 2006
6042006
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Articles 1–20