|MAP kinase signalling pathways in cancer|
AS Dhillon, S Hagan, O Rath, W Kolch
Oncogene 26 (22), 3279-3290, 2007
|Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions|
Biochemical Journal 351 (2), 289-305, 2000
|Protein kinase Cα activates RAF-1 by direct phosphorylation|
W Kolch, G Heidecker, G Kochs, R Hummel, H Vahidi, H Mischak, ...
Nature 364 (6434), 249-252, 1993
|Coordinating ERK/MAPK signalling through scaffolds and inhibitors|
Nature reviews Molecular cell biology 6 (11), 827-837, 2005
|Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP|
K Yeung, T Seitz, S Li, P Janosch, B McFerran, C Kaiser, F Fee, ...
Nature 401 (6749), 173-177, 1999
|Overexpression of protein kinase C-delta and-epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.|
H Mischak, JA Goodnight, W Kolch, G Martiny-Baron, C Schaechtle, ...
Journal of Biological Chemistry 268 (9), 6090-6096, 1993
|Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression|
A Kieser, HA Weich, G Brandner, D Marmé, W Kolch
Oncogene 9 (3), 963-970, 1994
|Signalling ballet in space and time|
BN Kholodenko, JF Hancock, W Kolch
Nature reviews Molecular cell biology 11 (6), 414-426, 2010
|Raf-1 protein kinase is required for growth of induced NIH/3T3 cells|
W Kolch, G Heidecker, P Lloyd, UR Rapp
Nature 349 (6308), 426-428, 1991
|The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity|
CJ Gloeckner, N Kinkl, A Schumacher, RJ Braun, E O'Neill, T Meitinger, ...
Human molecular genetics 15 (2), 223-232, 2006
|Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway|
RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch
Biochemical Journal 392 (2), 249-261, 2005
|Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease|
DM Good, P Zürbig, A Argiles, HW Bauer, G Behrens, JJ Coon, M Dakna, ...
Molecular & cellular proteomics 9 (11), 2424-2437, 2010
|Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein|
K Yeung, P Janosch, B McFerran, DW Rose, H Mischak, JM Sedivy, ...
Molecular and cellular biology 20 (9), 3079-3085, 2000
|Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells|
S Kao, RK Jaiswal, W Kolch, GE Landreth
Journal of Biological Chemistry 276 (21), 18169-18177, 2001
|Regulation and role of Raf-1/B-Raf heterodimerization|
LK Rushworth, AD Hindley, E O'Neill, W Kolch
Molecular and cellular biology 26 (6), 2262-2272, 2006
|Raf kinase inhibitor protein interacts with NF-κB-inducing kinase and TAK1 and inhibits NF-κB activation|
KC Yeung, DW Rose, AS Dhillon, D Yaros, M Gustafsson, D Chatterjee, ...
Molecular and cellular biology 21 (21), 7207-7217, 2001
|RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein|
D Matallanas, D Romano, K Yee, K Meissl, L Kucerova, D Piazzolla, ...
Molecular cell 27 (6), 962-975, 2007
|Epstein–Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade|
A Kieser, E Kilger, O Gires, M Ueffing, W Kolch, W Hammerschmidt
The EMBO journal 16 (21), 6478-6485, 1997
|Raf family kinases: old dogs have learned new tricks|
D Matallanas, M Birtwistle, D Romano, A Zebisch, J Rauch, ...
Genes & cancer 2 (3), 232-260, 2011
|Mechanism of inhibition of Raf-1 by protein kinase A|
S Häfner, HS Adler, H Mischak, P Janosch, G Heidecker, A Wolfman, ...
Molecular and cellular biology 14 (10), 6696-6703, 1994