Recovering gene interactions from single-cell data using data diffusion D Van Dijk, R Sharma, J Nainys, K Yim, P Kathail, AJ Carr, C Burdziak, ... Cell 174 (3), 716-729. e27, 2018 | 1505 | 2018 |
The emergent landscape of the mouse gut endoderm at single-cell resolution S Nowotschin, M Setty, YY Kuo, V Liu, V Garg, R Sharma, CS Simon, ... Nature 569 (7756), 361-367, 2019 | 345 | 2019 |
Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies SC Wei, NAAS Anang, R Sharma, MC Andrews, A Reuben, JH Levine, ... Proceedings of the National Academy of Sciences 116 (45), 22699-22709, 2019 | 319 | 2019 |
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer K Ganesh, H Basnet, Y Kaygusuz, AM Laughney, L He, R Sharma, ... Nature cancer 1 (1), 28-45, 2020 | 194 | 2020 |
MAGIC: A diffusion-based imputation method reveals gene-gene interactions in single-cell RNA-sequencing data D Dijk, J Nainys, R Sharma, P Kaithail, AJ Carr, KR Moon, L Mazutis, ... BioRxiv, 111591, 2017 | 181 | 2017 |
Negative co-stimulation constrains T cell differentiation by imposing boundaries on possible cell states SC Wei, R Sharma, NAAS Anang, JH Levine, Y Zhao, JJ Mancuso, ... Immunity 50 (4), 1084-1098. e10, 2019 | 100 | 2019 |
SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data S Persad, ZN Choo, C Dien, N Sohail, I Masilionis, R Chaligné, T Nawy, ... Nature Biotechnology 41 (12), 1746-1757, 2023 | 83 | 2023 |
MACHETE identifies interferon-encompassing chromosome 9p21. 3 deletions as mediators of immune evasion and metastasis FM Barriga, KM Tsanov, YJ Ho, N Sohail, A Zhang, T Baslan, AN Wuest, ... Nature Cancer 3 (11), 1367-1385, 2022 | 71 | 2022 |
Natural genetic variation reveals key features of epigenetic and transcriptional memory in virus-specific CD8 T cells J van der Veeken, Y Zhong, R Sharma, L Mazutis, P Dao, D Pe’er, ... Immunity 50 (5), 1202-1217. e7, 2019 | 53 | 2019 |
Adult human glioblastomas harbor radial glia-like cells R Wang, R Sharma, X Shen, AM Laughney, K Funato, PJ Clark, ... Stem Cell Reports 14 (2), 338-350, 2020 | 52 | 2020 |
Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors J Fisher, R Sharma, DW Don, M Barisa, MO Hurtado, P Abramowski, ... Science signaling 12 (598), eaax1872, 2019 | 43 | 2019 |
CD49b defines functionally mature Treg cells that survey skin and vascular tissues X Fan, B Moltedo, A Mendoza, AN Davydov, MB Faire, L Mazutis, ... Journal of Experimental Medicine 215 (11), 2796-2814, 2018 | 40 | 2018 |
Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement K Showalter, R Spiera, C Magro, P Agius, V Martyanov, JM Franks, ... Annals of the rheumatic diseases 80 (2), 228-237, 2021 | 27 | 2021 |
Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies A Glasner, SA Rose, R Sharma, H Gudjonson, T Chu, JA Green, ... Nature immunology 24 (6), 1020-1035, 2023 | 23 | 2023 |
Learning time-varying information flow from single-cell epithelial to mesenchymal transition data S Krishnaswamy, N Zivanovic, R Sharma, D Pe’er, B Bodenmiller PLoS One 13 (10), e0203389, 2018 | 21 | 2018 |
Quantum state synthesis of superconducting resonators R Sharma, FW Strauch Physical Review A 93 (1), 012342, 2016 | 19 | 2016 |
Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution ME Monberg, H Geiger, JJ Lee, R Sharma, A Semaan, V Bernard, J Wong, ... Nature communications 13 (1), 3652, 2022 | 18 | 2022 |
States that “look the same” with respect to every basis in a mutually unbiased set I Amburg, R Sharma, DM Sussman, WK Wootters Journal of Mathematical Physics 55 (12), 2014 | 18 | 2014 |
Age-related epithelial defects limit thymic function and regeneration AI Kousa, L Jahn, K Zhao, AE Flores, D Acenas, E Lederer, ... Nature Immunology 25 (9), 1593-1606, 2024 | 4 | 2024 |
Erratum:“states that ‘look the same’with respect to every basis in a mutually unbiased set”[J. Math. Phys. 55, 122206 (2014)] I Amburg, R Sharma, DM Sussman, WK Wootters Journal of Mathematical Physics 56 (3), 2015 | 3 | 2015 |