Mario L. Suva
Mario L. Suva
Associate Professor, Massachusetts General Hospital, Broad Institute, Harvard Medical School
Verified email at
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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ...
Science 344 (6190), 1396-1401, 2014
An integrative model of cellular states, plasticity, and genetics for glioblastoma
C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ...
Cell 178 (4), 835-849. e21, 2019
Insulator dysfunction and oncogene activation in IDH mutant gliomas
WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ...
Nature 529 (7584), 110-114, 2016
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ...
Nature 565 (7738), 234-239, 2019
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ...
Nature 539 (7628), 309-313, 2016
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
ML Suvā, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ...
Cell 157 (3), 580-594, 2014
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ...
Science 355 (6332), eaai8478, 2017
Epigenetic reprogramming in cancer
ML Suvā, N Riggi, BE Bernstein
Science 339 (6127), 1567-1570, 2013
Electrical and synaptic integration of glioma into neural circuits
HS Venkatesh, W Morishita, AC Geraghty, D Silverbush, SM Gillespie, ...
Nature 573 (7775), 539-545, 2019
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
EZH2 is essential for glioblastoma cancer stem cell maintenance
ML Suvā, N Riggi, M Janiszewska, I Radovanovic, P Provero, JC Stehle, ...
Cancer research 69 (24), 9211-9218, 2009
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
RL Flynn, KE Cox, M Jeitany, H Wakimoto, AR Bryll, NJ Ganem, F Bersani, ...
Science 347 (6219), 273-277, 2015
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell stem cell 20 (2), 233-246. e7, 2017
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
C Dostert, G Guarda, JF Romero, P Menu, O Gross, A Tardivel, ML Suva, ...
PloS one 4 (8), e6510, 2009
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
M Janiszewska, ML Suvā, N Riggi, RH Houtkooper, J Auwerx, ...
Genes & development 26 (17), 1926-1944, 2012
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ...
Nature medicine 26 (5), 792-802, 2020
Development of Ewing's sarcoma from primary bone marrow–derived mesenchymal progenitor cells
N Riggi, L Cironi, P Provero, ML Suvà, K Kaloulis, C Garcia-Echeverria, ...
Cancer research 65 (24), 11459-11468, 2005
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate
L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ...
Nature medicine 24 (8), 1192-1203, 2018
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma
N Riggi, B Knoechel, SM Gillespie, E Rheinbay, G Boulay, ML Suvā, ...
Cancer cell 26 (5), 668-681, 2014
Identification of cancer stem cells in Ewing's sarcoma
ML Suvà, N Riggi, JC Stehle, K Baumer, S Tercier, JM Joseph, D Suvà, ...
Cancer research 69 (5), 1776-1781, 2009
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