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Adrian  M. Dubuc, Ph.D
Adrian M. Dubuc, Ph.D
Roswell Park Comprehensive Cancer Center
Verified email at RoswellPark.Org
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Cited by
Cited by
Year
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
9722012
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6432014
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ...
Nature genetics 41 (4), 465-472, 2009
4942009
Clonal selection drives genetic divergence of metastatic medulloblastoma
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ...
Nature 482 (7386), 529-533, 2012
4852012
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ...
Cell 153 (5), 1064-1079, 2013
4362013
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ...
Acta neuropathologica 123, 615-626, 2012
4252012
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ...
The lancet oncology 14 (12), 1200-1207, 2013
4052013
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition
JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ...
Nature communications 7 (1), 11589, 2016
3832016
Institutional implementation of clinical tumor profiling on an unselected cancer population
LM Sholl, K Do, P Shivdasani, E Cerami, AM Dubuc, FC Kuo, EP Garcia, ...
JCI insight 1 (19), 2016
3822016
Cytogenetic prognostication within medulloblastoma subgroups
DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ...
Journal of clinical oncology 32 (9), 886-896, 2014
3582014
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
PA Northcott, T Hielscher, A Dubuc, S Mack, D Shih, M Remke, ...
Acta neuropathologica 122, 231-240, 2011
2732011
Molecular subgroups of medulloblastoma
PA Northcott, AM Dubuc, S Pfister, MD Taylor
Expert review of neurotherapeutics 12 (7), 871-884, 2012
2012012
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126, 917-929, 2013
1982013
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
AM Dubuc, M Remke, A Korshunov, PA Northcott, SH Zhan, ...
Acta neuropathologica 125, 373-384, 2013
1902013
MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma
S Venkataraman, DK Birks, I Balakrishnan, I Alimova, PS Harris, PR Patel, ...
Journal of Biological Chemistry 288 (3), 1918-1928, 2013
1232013
A molecularly integrated grade for meningioma
J Driver, SE Hoffman, S Tavakol, E Woodward, EA Maury, V Bhave, ...
Neuro-oncology 24 (5), 796-808, 2022
1192022
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells
PS Harris, S Venkataraman, I Alimova, DK Birks, AM Donson, J Knipstein, ...
BMC cancer 12, 1-13, 2012
1032012
Medulloblastoma subgroups remain stable across primary and metastatic compartments
X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ...
Acta neuropathologica 129, 449-457, 2015
1012015
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics …
P Horak, M Griffith, AM Danos, BA Pitel, S Madhavan, X Liu, C Chow, ...
Genetics in Medicine 24 (5), 986-998, 2022
992022
The current state of clinical interpretation of sequence variants
DC Hoskinson, AM Dubuc, H Mason-Suares
Current opinion in genetics & development 42, 33-39, 2017
962017
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