| Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9 MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ... Cell reports 17 (5), 1453-1461, 2016 | 276 | 2016 |
| Mutant NPM1 maintains the leukemic state through HOX expression L Brunetti, MC Gundry, D Sorcini, AG Guzman, YH Huang, ... Cancer cell 34 (3), 499-512. e9, 2018 | 239 | 2018 |
| DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A YH Huang, J Su, Y Lei, L Brunetti, MC Gundry, X Zhang, M Jeong, W Li, ... Genome biology 18, 1-11, 2017 | 210 | 2017 |
| NPM1-mutated acute myeloid leukemia: from bench to bedside B Falini, L Brunetti, P Sportoletti, MP Martelli Blood, The Journal of the American Society of Hematology 136 (15), 1707-1721, 2020 | 190 | 2020 |
| Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... Blood, The Journal of the American Society of Hematology 137 (5), 624-636, 2021 | 177 | 2021 |
| DNMT3A in Leukemia L Brunetti, MC Gundry, MA Goodell Cold Spring Harbor perspectives in medicine 7 (2), a030320, 2017 | 173 | 2017 |
| Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells MP Martelli, I Gionfriddo, F Mezzasoma, F Milano, S Pierangeli, F Mulas, ... Blood, The Journal of the American Society of Hematology 125 (22), 3455-3465, 2015 | 157 | 2015 |
| CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression K Fousek, J Watanabe, SK Joseph, A George, X An, TT Byrd, JS Morris, ... Leukemia 35 (1), 75-89, 2021 | 137 | 2021 |
| CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice MP Martelli, V Pettirossi, C Thiede, E Bonifacio, F Mezzasoma, D Cecchini, ... Blood, The Journal of the American Society of Hematology 116 (19), 3907-3922, 2010 | 136 | 2010 |
| Aerobic plus resistance exercise in obese older adults improves muscle protein synthesis and preserves myocellular quality despite weight loss G Colleluori, L Aguirre, U Phadnis, K Fowler, R Armamento-Villareal, ... Cell metabolism 30 (2), 261-273. e6, 2019 | 103 | 2019 |
| Dactinomycin in NPM1-mutated acute myeloid leukemia B Falini, L Brunetti, MP Martelli New England Journal of Medicine 373 (12), 1180-1182, 2015 | 73 | 2015 |
| Nutrient‐sensitive transcription factors TFEB and TFE 3 couple autophagy and metabolism to the peripheral clock N Pastore, A Vainshtein, NJ Herz, T Huynh, L Brunetti, TJ Klisch, ... The EMBO journal 38 (12), e101347, 2019 | 66 | 2019 |
| CD200/OX2, a cell surface molecule with immuno-regulatory function, is consistently expressed on hairy cell leukaemia neoplastic cells L Brunetti, R Di Noto, G Abate, M Gorrese, A Gravetti, M Raia, G Scalia, ... British journal of haematology, 665-667, 2009 | 61 | 2009 |
| Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics B Falini, P Sportoletti, L Brunetti, MP Martelli British journal of haematology 170 (3), 305-322, 2015 | 54 | 2015 |
| How I diagnose and treat NPM1-mutated AML B Falini, L Brunetti, MP Martelli Blood, The Journal of the American Society of Hematology 137 (5), 589-599, 2021 | 51 | 2021 |
| Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma Q Tan, L Brunetti, MWC Rousseaux, HC Lu, YW Wan, JP Revelli, Z Liu, ... Proceedings of the National Academy of Sciences 115 (7), E1511-E1519, 2018 | 49 | 2018 |
| Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin L Brunetti, V Di Battista, A Venanzi, G Schiavoni, MP Martelli, S Ascani, ... Leukemia 31 (5), 1238-1240, 2017 | 49 | 2017 |
| Actinomycin D targets NPM1c-primed mitochondria to restore PML-driven senescence in AML therapy HC Wu, D Rérolle, C Berthier, R Hleihel, T Sakamoto, S Quentin, ... Cancer discovery 11 (12), 3198-3213, 2021 | 43 | 2021 |
| TFEB regulates murine liver cell fate during development and regeneration N Pastore, T Huynh, NJ Herz, A Calcagni’, TJ Klisch, L Brunetti, KH Kim, ... Nature communications 11 (1), 2461, 2020 | 39 | 2020 |
| Highly efficient gene disruption of murine and human hematopoietic progenitor cells by CRISPR/Cas9 L Brunetti, MC Gundry, A Kitano, D Nakada, MA Goodell JoVE (Journal of Visualized Experiments), e57278, 2018 | 38 | 2018 |
Brunangelo FaliniProfessor of Hematology, University of Perugia, ItalyVerified email at unipg.it
