Follow
Hojong Yoon
Hojong Yoon
Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
TB Faust*, H Yoon*, RP Nowak, KA Donovan, Z Li, Q Cai, NA Eleuteri, ...
Nature chemical biology 16 (1), 7-14, 2020
1562020
Small-molecule-induced polymerization triggers degradation of BCL6
M Słabicki*, H Yoon*, J Koeppel*, L Nitsch, SSR Burman, C Di Genua, ...
Nature 588 (7836), 164-168, 2020
1532020
Targeted protein degradation as a powerful research tool in basic biology and drug target discovery
T Wu, H Yoon, Y Xiong, SE Dixon-Clarke, RP Nowak, ES Fischer
Nature Structural & Molecular Biology 27 (7), 605-614, 2020
1322020
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
G Du, J Jiang, NJ Henning, N Safaee, E Koide, RP Nowak, KA Donovan, ...
Cell chemical biology 29 (10), 1470-1481. e31, 2022
372022
A pyrazolo [3, 4-d] pyrimidin-4-amine derivative containing an isoxazole moiety is a selective and potent inhibitor of RET gatekeeper mutants
H Yoon*, Y Kwak*, S Choi, H Cho, ND Kim, T Sim
Journal of medicinal chemistry 59 (1), 358-373, 2016
312016
Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach
A Nonami, M Sattler, E Weisberg, Q Liu, J Zhang, MP Patricelli, ...
Blood, The Journal of the American Society of Hematology 125 (20), 3133-3143, 2015
312015
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
YD Li, MW Ma, MM Hassan, M Hunkeler, M Teng, K Puvar, R Lumpkin, ...
BioRxiv, 2023
222023
Rationally designed covalent BCL6 inhibitor that targets a tyrosine residue in the homodimer interface
M Teng, SB Ficarro, H Yoon, J Che, J Zhou, ES Fischer, JA Marto, ...
ACS Medicinal Chemistry Letters 11 (6), 1269-1273, 2020
222020
Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor
H Yoon*, I Shin*, Y Nam, ND Kim, KB Lee, T Sim
European journal of medicinal chemistry 125, 1145-1155, 2017
202017
Asymmetric synthesis of (+)-lentiginosine using a chiral aziridine based approach
H Yoon, KS Cho, T Sim
Tetrahedron: Asymmetry 25 (6-7), 497-502, 2014
192014
Double blockade of glioma cell proliferation and migration by temozolomide conjugated with NPPB, a chloride channel blocker
M Park, C Song, H Yoon, KH Choi
ACS Chemical Neuroscience 7 (3), 275-285, 2016
182016
Identification of Thieno [3, 2-d] pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3
H Cho*, I Shin*, H Yoon*, E Jeon, J Lee, Y Kim, SS Ryu, C Song, ...
Journal of Medicinal Chemistry, 2021
152021
Heteroarylamine derivatives as protein kinase inhibitors
TB Sim, HJ Yoon, JH Yoon, WY Hur, EJ Roh, YU Kwak
US Patent 9,586,936, 2017
112017
BTBBCL6 dimers as building blocks for reversible drug-induced protein oligomerization
L Nitsch, P Jensen, H Yoon, J Koeppel, SSR Burman, ES Fischer, ...
Cell Reports Methods 2 (4), 2022
72022
Identification of novel resorcinol amide derivatives as potent and specific pyruvate dehydrogenase kinase (PDHK) inhibitors
H Cho, I Shin, K Cho, H Yoon, EK Yoo, MJ Kim, S Park, IK Lee, ND Kim, ...
Journal of Medicinal Chemistry 62 (18), 8461-8479, 2019
72019
Stereoselective synthesis of (+)-polyoxamic acid starting with a chiral aziridine
H Yoon, T Sim
Synthesis, 3276-3280, 2013
72013
In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3
G Hwang, H Kim, H Yoon, C Song, DK Lim, T Sim, J Lee
International Journal of Nanomedicine, 5345-5357, 2017
52017
Asymmetric Synthesis of (−)-6-Desmethyl-Fluvirucinine A1 Via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions
H Moon*, H Yoon*, C Lim, J Jang, JJ Yi, JK Lee, J Lee, Y Na, WS Son, ...
Molecules 23 (9), 2351, 2018
42018
Induced protein degradation for therapeutics: past, present, and future
H Yoon, JC Rutter, YD Li, BL Ebert
The Journal of Clinical Investigation 134 (1), 2024
32024
2, 3, 5-substituted thiophene compound as protein kinase inhibitor
TB Sim, WY Hur, C man Song, HJ Yoon, SH Choi, HN Cho, HG Choi, ...
US Patent 10,442,796, 2019
22019
The system can't perform the operation now. Try again later.
Articles 1–20