Electrochemical synthesis of hindered primary and secondary amines via proton-coupled electron transfer D Lehnherr, Y Lam, MC Nicastri, J Liu, JA Newman, EL Regalado, ... Journal of the American Chemical Society 142 (1), 468-478, 2019 | 95 | 2019 |
Enzymatic kinetic resolution of piperidine atropisomers: synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336 B Morgan, A Zaks, DR Dodds, J Liu, R Jain, S Megati, FG Njoroge, ... The Journal of Organic Chemistry 65 (18), 5451-5459, 2000 | 79 | 2000 |
Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral β-amino acid derivatives N Ikemoto, DM Tellers, SD Dreher, J Liu, A Huang, NR Rivera, E Njolito, ... Journal of the American Chemical Society 126 (10), 3048-3049, 2004 | 77 | 2004 |
Improved syntheses of α-BOC-aminoketones from α-BOC-amino-Weinreb amides using a pre-deprotonation protocol J Liu, N Ikemoto, D Petrillo, JD Armstrong III Tetrahedron letters 43 (46), 8223-8226, 2002 | 69 | 2002 |
Extending the range of supercritical fluid chromatography by use of water-rich modifiers J Liu, EL Regalado, I Mergelsberg, CJ Welch Organic & biomolecular chemistry 11 (30), 4925-4929, 2013 | 67 | 2013 |
Chaotropic effects in sub/supercritical fluid chromatography via ammonium hydroxide in water-rich modifiers: enabling separation of peptides and highly polar pharmaceuticals at … J Liu, AA Makarov, R Bennett, IA Haidar Ahmad, J DaSilva, M Reibarkh, ... Analytical chemistry 91 (21), 13907-13915, 2019 | 60 | 2019 |
Synthesis of [1, 2, 4] triazolo [4, 3-α] piperazines via highly reactive chloromethyloxadiazoles J Balsells, L DiMichele, J Liu, M Kubryk, K Hansen, JD Armstrong Organic letters 7 (6), 1039-1042, 2005 | 60 | 2005 |
Practical routes to the triarylsulfonyl chloride intermediate of a β3 adrenergic receptor agonist N Ikemoto, J Liu, KMJ Brands, JM McNamara, PJ Reider Tetrahedron 59 (8), 1317-1325, 2003 | 47 | 2003 |
Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry EL Regalado, MC Kozlowski, JM Curto, T Ritter, MG Campbell, ... Organic & Biomolecular Chemistry 12 (14), 2161-2166, 2014 | 46 | 2014 |
A facile method for the preparation of 4-hydroxy-Δ2-isoxazolines via a cycloaddition/oxidation procedure employing nitrile oxides and vinylboronic esters RH Wallace, J Liu Tetrahedron Letters 35 (41), 7493-7496, 1994 | 38 | 1994 |
An efficient method for the preparation of optically active 4-hydroxy-Δ2-isoxazolines RH Wallace, J Liu, KK Zong, A Eddings Tetrahedron letters 38 (39), 6791-6794, 1997 | 35 | 1997 |
Enhanced fluidity liquid chromatography: A guide to scaling up from analytical to preparative separations R Bennett, M Biba, J Liu, IAH Ahmad, MB Hicks, EL Regalado Journal of Chromatography A 1595, 190-198, 2019 | 34 | 2019 |
Total synthesis of chaetoglobin A via catalytic, atroposelective oxidative phenol coupling H Kang, C Torruellas, J Liu, MC Kozlowski Organic letters 20 (18), 5554-5558, 2018 | 34 | 2018 |
Sodium percarbonate: A multifunctional reagent for the preparation of optically active 4-hydroxy-Δ2-isoxazolines J Liu, A Eddings, RH Wallace Tetrahedron letters 38 (39), 6795-6798, 1997 | 34 | 1997 |
Convergent Kilo-Scale Synthesis of a Potent Renin Inhibitor for the Treatment of Hypertension LC Campeau, SJ Dolman, D Gauvreau, E Corley, J Liu, EN Guidry, ... Organic Process Research & Development 15 (5), 1138-1148, 2011 | 33 | 2011 |
Asymmetric Syntheses IV: Enantioselective Synthesis of (R)-Benzylic Amines Via Alkylation of D-Camphor Ketimine J Yaozhong, L Guilan, L Jinchu, ZC Chengdu Synthetic Communications 17 (13), 1545-1548, 1987 | 32 | 1987 |
A novel enantioselective alkylation and its application to the synthesis of an anticancer agent SC Kuo, F Chen, D Hou, A Kim-Meade, C Bernard, J Liu, S Levy, GG Wu The Journal of Organic Chemistry 68 (12), 4984-4987, 2003 | 31 | 2003 |
Expanding the range of sub/supercritical fluid chromatography: advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis GL Losacco, JO DaSilva, J Liu, EL Regalado, JL Veuthey, D Guillarme Journal of Chromatography A 1642, 462048, 2021 | 28 | 2021 |
Highly selective synthesis of 2-substituted-5-hydroxy-6-oxo-1, 6-dihydropyrimidine-4-carboxylic acid derivatives using a novel protected dihydroxyfumarate SD Dreher, N Ikemoto, V Gresham, J Liu, PG Dormer, J Balsells, D Mathre, ... Tetrahedron letters 45 (31), 6023-6025, 2004 | 18 | 2004 |
Improved preparation of a key hydroxylamine intermediate for relebactam: Rate enhancement of benzyl ether hydrogenolysis with dabco J Yin, M Weisel, Y Ji, Z Liu, J Liu, DJ Wallace, F Xu, BD Sherry, N Yasuda Organic Process Research & Development 22 (3), 273-277, 2018 | 16 | 2018 |