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Roshan Kumar
Roshan Kumar
Research Fellow
Verified email at umich.edu
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Cited by
Cited by
Year
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron
R Singhal, SR Mitta, NK Das, SA Kerk, P Sajjakulnukit, S Solanki, ...
The Journal of clinical investigation 131 (12), 2021
1262021
S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation
R Kumar, DK Jangir, G Verma, S Shekhar, P Hanpude, S Kumar, ...
Scientific reports 7 (1), 44558, 2017
662017
Regulation of the redox metabolome and thiol proteome by hydrogen sulfide
R Kumar, R Banerjee
Critical reviews in biochemistry and molecular biology 56 (3), 221-235, 2021
322021
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer
HN Bell, AK Huber, R Singhal, N Korimerla, RJ Rebernick, R Kumar, ...
Cell metabolism 35 (1), 134-149. e6, 2023
302023
A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H2S oxidation
R Kumar, AP Landry, A Guha, V Vitvitsky, HJ Lee, K Seike, P Reddy, ...
Journal of Biological Chemistry 298 (1), 2022
302022
Partially oxidized DJ-1 inhibits α-synuclein nucleation and remodels mature α-synuclein fibrils in vitro
R Kumar, S Kumar, P Hanpude, AK Singh, T Johari, S Majumder, TK Maiti
Communications biology 2 (1), 395, 2019
272019
The mitochondrial NADH pool is involved in hydrogen sulfide signaling and stimulation of aerobic glycolysis
V Vitvitsky, R Kumar, M Libiad, A Maebius, AP Landry, R Banerjee
Journal of Biological Chemistry 296, 2021
252021
Ellagic acid inhibits α-synuclein aggregation at multiple stages and reduces its cytotoxicity
S Kumar, R Kumar, M Kumari, R Kumari, S Saha, NS Bhavesh, TK Maiti
ACS Chemical Neuroscience 12 (11), 1919-1930, 2021
222021
Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease
R Kumari, R Kumar, S Kumar, AK Singh, P Hanpude, D Jangir, TK Maiti
Journal of Biological Chemistry 295 (11), 3466-3484, 2020
222020
Extracellular α-synuclein disrupts membrane nanostructure and promotes S-nitrosylation-induced neuronal cell death
R Kumar, R Kumari, S Kumar, DK Jangir, TK Maiti
Biomacromolecules 19 (4), 1118-1129, 2018
212018
Role of sporadic Parkinson disease associated mutations A18T and A29S in enhanced α-Synuclein fibrillation and cytotoxicity
S Kumar, DK Jangir, R Kumar, M Kumari, NS Bhavesh, TK Maiti
ACS Chemical Neuroscience 9 (2), 230-240, 2018
202018
Hydrogen sulfide stimulates lipid biogenesis from glutamine that is dependent on the mitochondrial NAD (P) H pool
S Carballal, V Vitvitsky, R Kumar, DA Hanna, M Libiad, A Gupta, ...
Journal of Biological Chemistry 297 (2), 2021
152021
A Metabolic Paradigm for Hydrogen Sulfide Signaling via Electron Transport Chain Plasticity
D Hanna, R Kumar, R Banerjee
Antioxidants & Redox Signaling 38 (1-3), 57-67, 2023
132023
Gas regulation of complex II reversal via electron shunting to fumarate in the mammalian ETC
R Banerjee, R Kumar
Trends in biochemical sciences 47 (8), 689-698, 2022
102022
S-nitrosylation of OTUB1 alters its stability and Ubc13 binding
R Kumari, R Kumar, AK Dey, S Saha, TK Maiti
ACS Chemical Neuroscience 13 (10), 1517-1525, 2022
72022
A redox cycle with complex II promotes sulfide quinone oxidoreductase dependent H2S oxidation
R Kumar, AP Landry, A Guha, V Vitvitsky, HJ Lee, K Seike, P Reddy, ...
bioRxiv, 2021.09. 08.459449, 2021
32021
Sulfide oxidation promotes hypoxic angiogenesis and neovascularization
R Kumar, V Vitvitsky, A Sethaudom, R Singhal, S Solanki, S Alibeckoff, ...
Nature Chemical Biology, 1-11, 2024
12024
H2S preconditioning induces long-lived perturbations in O2 metabolism
DA Hanna, J Diessl, A Guha, R Kumar, A Andren, C Lyssiotis, R Banerjee
Proceedings of the National Academy of Sciences 121 (12), e2319473121, 2024
12024
Rapid HPLC method reveals dynamic shifts in coenzyme Q redox state
V Vitvitsky, R Kumar, J Diessl, DA Hanna, R Banerjee
Journal of Biological Chemistry, 107301, 2024
2024
Protein redox modification and its implication in neurodegenerative diseases
R Kumar
Manipal, 0
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Articles 1–20