| A role for α-synuclein in the regulation of dopamine biosynthesis RG Perez, JC Waymire, E Lin, JJ Liu, F Guo, MJ Zigmond Journal of Neuroscience 22 (8), 3090-3099, 2002 | 965 | 2002 |
| Mutagenesis identifies new signals for β-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Aβ42 RG Perez, S Soriano, JD Hayes, B Ostaszewski, W Xia, DJ Selkoe, ... Journal of Biological Chemistry 274 (27), 18851-18856, 1999 | 543 | 1999 |
| The β-amyloid precursor protein of Alzheimer’s disease enhances neuron viability and modulates neuronal polarity RG Perez, H Zheng, LHT Van der Ploeg, EH Koo Journal of Neuroscience 17 (24), 9407-9414, 1997 | 360 | 1997 |
| Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease W Xia, J Zhang, R Perez, EH Koo, DJ Selkoe Proceedings of the National Academy of Sciences 94 (15), 8208-8213, 1997 | 350 | 1997 |
| α-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells XM Peng, R Tehranian, P Dietrich, L Stefanis, RG Perez Journal of cell science 118 (15), 3523-3530, 2005 | 338 | 2005 |
| The contribution of alpha synuclein to neuronal survival and function–Implications for Parkinson's disease MJ Benskey, RG Perez, FP Manfredsson Journal of neurochemistry 137 (3), 331-359, 2016 | 261 | 2016 |
| Could a loss of α‐synuclein function put dopaminergic neurons at risk? RG Perez, TG Hastings Journal of neurochemistry 89 (6), 1318-1324, 2004 | 194 | 2004 |
| Enhanced Release of Amyloid-Protein from Codon 670/671 Swedish Mutant-Amyloid Precursor Protein Occurs in Both Secretory and Endocytic Pathways (∗) RG Perez, SL Squazzo, EH Koo Journal of Biological Chemistry 271 (15), 9100-9107, 1996 | 166 | 1996 |
| Serine 129 phosphorylation reduces the ability of α-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo H Lou, SE Montoya, TNM Alerte, J Wang, J Wu, X Peng, CS Hong, ... Journal of Biological Chemistry 285 (23), 17648-17661, 2010 | 146 | 2010 |
| Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death H Lou, P Fan, RG Perez, H Lou Bioorganic & medicinal chemistry 19 (13), 4021-4027, 2011 | 141 | 2011 |
| Increased dopamine turnover after partial loss of dopaminergic neurons: compensation or toxicity? MJ Zigmond, TG Hastings, RG Perez Parkinsonism & related disorders 8 (6), 389-393, 2002 | 136 | 2002 |
| Alpha‐synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells R Tehranian, SE Montoya, AD Van Laar, TG Hastings, RG Perez Journal of neurochemistry 99 (4), 1188-1196, 2006 | 134 | 2006 |
| α-Synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice TNM Alerte, AA Akinfolarin, EE Friedrich, SA Mader, CS Hong, RG Perez Neuroscience letters 435 (1), 24-29, 2008 | 127 | 2008 |
| α-Synuclein binds the KATP channel at insulin-secretory granules and inhibits insulin secretion X Geng, H Lou, J Wang, L Li, AL Swanson, M Sun, D Beers-Stolz, ... American Journal of Physiology-Endocrinology and Metabolism 300 (2), E276-E286, 2011 | 106 | 2011 |
| Effects of GDNF on 6‐OHDA‐induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK SD Ugarte, E Lin, E Klann, MJ Zigmond, RG Perez Journal of neuroscience research 73 (1), 105-112, 2003 | 100 | 2003 |
| S‐allyl cysteine activates the Nrf2‐dependent antioxidant response and protects neurons against ischemic injury in vitro and in vivo H Shi, X Jing, X Wei, RG Perez, M Ren, X Zhang, H Lou Journal of neurochemistry 133 (2), 298-308, 2015 | 91 | 2015 |
| 14-3-3ζ contributes to tyrosine hydroxylase activity in MN9D cells: Localization of dopamine regulatory proteins to mitochondria J Wang, H Lou, CJ Pedersen, AD Smith, RG Perez Journal of biological chemistry 284 (21), 14011-14019, 2009 | 89 | 2009 |
| Tenascin in the developing chick visual system: distribution and potential role as a modulator of retinal axon growth RG Perez, W Halfter Developmental biology 156 (1), 278-292, 1993 | 81 | 1993 |
| FTY720/fingolimod reduces synucleinopathy and improves gut motility in A53T mice: contributions of pro-brain-derived neurotrophic factor (Pro-BDNF) and mature BDNF G Vidal-Martínez, J Vargas-Medrano, C Gil-Tommee, D Medina, NT Garza, ... Journal of Biological Chemistry 291 (39), 20811-20821, 2016 | 74 | 2016 |
| X11α modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence GD King, RG Perez, ML Steinhilb, JR Gaut, RS Turner Neuroscience 120 (1), 143-154, 2003 | 70 | 2003 |
Michael ZigmondUniversity of PittsburghVerified email at pitt.edu
