Shin-Heng Chiou
Shin-Heng Chiou
Assistant Professor, Rutgers University
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Organoid modeling of the tumor immune microenvironment
JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ...
Cell 175 (7), 1972-1988. e16, 2018
Nfib promotes metastasis through a widespread increase in chromatin accessibility
SK Denny, D Yang, CH Chuang, JJ Brady, JS Lim, BM Grüner, SH Chiou, ...
Cell 166 (2), 328-342, 2016
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
SH Chiou, IP Winters, J Wang, S Naranjo, C Dudgeon, FB Tamburini, ...
Genes & development 29 (14), 1576-1585, 2015
Gpr124 is essential for blood–brain barrier integrity in central nervous system disease
J Chang, MR Mancuso, C Maier, X Liang, K Yuki, LU Yang, JW Kwong, ...
Nature medicine 23 (4), 450-460, 2017
Comprehensive T cell repertoire characterization of non-small cell lung cancer
A Reuben, J Zhang, SH Chiou, RM Gittelman, J Li, WC Lee, J Fujimoto, ...
Nature communications 11 (1), 603, 2020
Up-regulation of inhibitory natural killer receptors CD94/NKG2A with suppressed intracellular perforin expression of tumor-infiltrating CD8+ T lymphocytes in human cervical …
BC Sheu, SH Chiou, HH Lin, SN Chow, SC Huang, HN Ho, SM Hsu
Cancer Research 65 (7), 2921-2929, 2005
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis
CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ...
Nature medicine 23 (3), 291-300, 2017
Current concepts of tumor-infiltrating lymphocytes in human malignancies
SH Chiou, BC Sheu, WC Chang, SC Huang, H Hong-Nerng
Journal of reproductive immunology 67 (1-2), 35-50, 2005
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
J Li, M Zaslavsky, Y Su, J Guo, MJ Sikora, V van Unen, A Christophersen, ...
Science 376 (6590), eabi9591, 2022
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity
IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ...
Nature communications 8 (1), 2053, 2017
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ...
Immunity 54 (3), 586-602. e8, 2021
An in vivo multiplexed small-molecule screening platform
BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ...
Nature methods 13 (10), 883-889, 2016
BLIMP1 induces transient metastatic heterogeneity in pancreatic cancer
SH Chiou, VI Risca, GX Wang, D Yang, BM Grüner, AS Kathiria, RK Ma, ...
Cancer discovery 7 (10), 1184-1199, 2017
Obligate progression precedes lung adenocarcinoma dissemination
DR Caswell, CH Chuang, D Yang, SH Chiou, S Cheemalavagu, ...
Cancer discovery 4 (7), 781-789, 2014
In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls
W Jiang, JR Birtley, SC Hung, W Wang, SH Chiou, C Macaubas, ...
Nature communications 10 (1), 5247, 2019
Integration of high-risk human papillomavirus DNA correlates with HLA genotype aberration and reduced HLA class I molecule expression in human cervical carcinoma
BC Sheu, SH Chiou, WC Chang, SN Chow, HH Lin, RJ Chen, SC Huang, ...
Clinical Immunology 115 (3), 295-301, 2005
Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance
SH Chiou, M Dorsch, E Kusch, S Naranjo, MM Kozak, AC Koong, ...
Scientific reports 8 (1), 14008, 2018
Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis
P Shahi, D Park, AC Pond, M Seethammagari, SH Chiou, K Cho, ...
PloS one 7 (1), e30814, 2012
Expression of inhibitory natural killer receptors on tumor-infiltrating CD8+ T lymphocyte lineage in human endometrial carcinoma
WC Chang, SC Huang, PL Torng, DY Chang, WC Hsu, SH Chiou, ...
International Journal of Gynecologic Cancer 15 (6), 2005
The E3 ligase c‐Cbl regulates dendritic cell activation
SH Chiou, P Shahi, RT Wagner, H Hu, N Lapteva, M Seethammagari, ...
EMBO reports 12 (9), 971-979, 2011
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