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Charlie Lees
Charlie Lees
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Year
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
52212012
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ...
Nature genetics 42 (12), 1118-1125, 2010
31562010
Guidelines for the management of inflammatory bowel disease in adults
C Mowat, A Cole, AL Windsor, T Ahmad, I Arnott, R Driscoll, S Mitton, ...
Gut 60 (5), 571-607, 2011
17632011
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ...
Nature genetics 43 (3), 246-252, 2011
17202011
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
M Parkes, JC Barrett, NJ Prescott, M Tremelling, CA Anderson, SA Fisher, ...
Nature genetics 39 (7), 830-832, 2007
14422007
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ...
Nature genetics 39 (11), 1329-1337, 2007
14332007
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
12582017
Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease
JF Rahier, F Magro, C Abreu, A Armuzzi, S Ben-Horin, Y Chowers, ...
Journal of Crohn's and Colitis 8 (6), 443-468, 2014
10212014
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
Nature 464 (7289), 713-720, 2010
9362010
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ...
The Lancet 387 (10014), 156-167, 2016
8462016
New IBD genetics: common pathways with other diseases
CW Lees, JC Barrett, M Parkes, J Satsangi
Gut 60 (12), 1739-1753, 2011
8042011
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
Data and Analysis Group: Spencer Chris CA chris. spencer@ well. ox. ac. uk 5 ...
Nature genetics 41 (12), 1330-1334, 2009
6312009
International IBD Genetics Consortium (IIBDGC). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
6302012
Fine-mapping inflammatory bowel disease loci to single-variant resolution
H Huang, M Fang, L Jostins, M Umićević Mirkov, G Boucher, ...
Nature 547 (7662), 173-178, 2017
6182017
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019
5912019
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
SA Fisher, M Tremelling, CA Anderson, R Gwilliam, S Bumpstead, ...
Nature genetics 40 (6), 710-712, 2008
5472008
The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing
NA Kennedy, AW Walker, SH Berry, SH Duncan, FM Farquarson, P Louis, ...
PloS one 9 (2), e88982, 2014
3412014
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172-179, 2015
3382015
HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease
A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ...
Gastroenterology 158 (1), 189-199, 2020
3152020
European Crohn’s and Colitis Organisation (ECCO)
JF Rahier, F Magro, C Abreu, A Armuzzi, S Ben-Horin, Y Chowers, ...
Second European evidence-based consensus on the prevention, diagnosis and …, 2014
3042014
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