| Molecular features of the copper binding sites in the octarepeat domain of the prion protein CS Burns, E Aronoff-Spencer, CM Dunham, P Lario, NI Avdievich, ... Biochemistry 41 (12), 3991-4001, 2002 | 498 | 2002 |
| Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis TS Kang, D Georgieva, N Genov, MT Murakami, M Sinha, RP Kumar, ... The FEBS journal 278 (23), 4544-4576, 2011 | 363 | 2011 |
| Crystal structure of the DNA modifying enzyme beta‐glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose. A Vrielink, W Rüger, HP Driessen, PS Freemont The EMBO journal 13 (15), 3413-3422, 1994 | 348 | 1994 |
| The structure of l‐amino acid oxidase reveals the substrate trajectory into an enantiomerically conserved active site PD Pawelek, J Cheah, R Coulombe, P Macheroux, S Ghisla, A Vrielink The EMBO journal, 2000 | 325 | 2000 |
| Crystal structure of cholesterol oxidase from Brevibacterium sterolicum refined at 1.8 Å resolution A Vrielink, LF Lloyd, DM Blow Journal of molecular biology 219 (3), 533-554, 1991 | 260 | 1991 |
| Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases J Li, A Vrielink, P Brick, DM Blow Biochemistry 32 (43), 11507-11515, 1993 | 259 | 1993 |
| Crystal structure of LAAO from Calloselasma rhodostoma with an L-phenylalanine substrate: insights into structure and mechanism IM Moustafa, S Foster, AY Lyubimov, A Vrielink Journal of molecular biology 364 (5), 991-1002, 2006 | 185 | 2006 |
| Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox … PI Lario, N Sampson, A Vrielink Journal of molecular biology 326 (5), 1635-1650, 2003 | 171 | 2003 |
| Crystal Structure Determination of Cholesterol Oxidase from Streptomyces and Structural Characterization of Key Active Site Mutants, QK Yue, IJ Kass, NS Sampson, A Vrielink Biochemistry 38 (14), 4277-4286, 1999 | 170 | 1999 |
| Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair R Coulombe, KQ Yue, S Ghisla, A Vrielink Journal of Biological Chemistry 276 (32), 30435-30441, 2001 | 153 | 2001 |
| Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding A Anandan, GL Evans, K Condic-Jurkic, ML O’Mara, CM John, NJ Phillips, ... Proceedings of the National Academy of Sciences 114 (9), 2218-2223, 2017 | 133 | 2017 |
| Cholesterol oxidase: biochemistry and structural features A Vrielink, S Ghisla The FEBS journal 276 (23), 6826-6843, 2009 | 133 | 2009 |
| Crystal structure of a bifunctional aldolase–dehydrogenase: Sequestering a reactive and volatile intermediate BA Manjasetty, J Powlowski, A Vrielink Proceedings of the National Academy of Sciences 100 (12), 6992-6997, 2003 | 127 | 2003 |
| Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomes C Carrie, E Giraud, O Duncan, L Xu, Y Wang, S Huang, R Clifton, ... Journal of Biological Chemistry 285 (46), 36138-36148, 2010 | 126 | 2010 |
| The structure of the neisserial lipooligosaccharide phosphoethanolamine transferase A (LptA) required for resistance to polymyxin C Wanty, A Anandan, S Piek, J Walshe, J Ganguly, RW Carlson, ... Journal of molecular biology 425 (18), 3389-3402, 2013 | 122 | 2013 |
| Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity B Ahvazi, R COULOMBE, M Delarge, M VEDADI, L ZHANG, E Meighen, ... Biochemical Journal 349 (3), 853-861, 2000 | 106 | 2000 |
| The binding and release of oxygen and hydrogen peroxide are directed by a hydrophobic tunnel in cholesterol oxidase L Chen, AY Lyubimov, L Brammer, A Vrielink, NS Sampson Biochemistry 47 (19), 5368-5377, 2008 | 101 | 2008 |
| Structure and characterization of the glycan moiety of L‐amino‐acid oxidase from the Malayan pit viper Calloselasma rhodostoma A Geyer, TB Fitzpatrick, PD Pawelek, K Kitzing, A Vrielink, S Ghisla, ... European Journal of Biochemistry 268 (14), 4044-4053, 2001 | 86 | 2001 |
| Cholesterol oxidases: a study of nature's approach to protein design NS Sampson, A Vrielink Accounts of chemical research 36 (9), 713-722, 2003 | 80 | 2003 |
| Detergents in membrane protein purification and crystallisation A Anandan, A Vrielink The next generation in membrane protein structure determination, 13-28, 2016 | 64 | 2016 |
Nicole SampsonUniversity Professor of Chemistry, University of RochesterVerified email at rochester.edu
