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yue, Hong
yue, Hong
Dana-Farber Cancer Institute/Harvard Medical School
Verified email at dfci.harvard.edu
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Cited by
Year
Mapping the degradable kinome provides a resource for expedited degrader development
KA Donovan, FM Ferguson, JW Bushman, NA Eleuteri, D Bhunia, SS Ryu, ...
Cell 183 (6), 1714-1731. e10, 2020
1702020
Comprehensive characterization of protein–protein interactions perturbed by disease mutations
F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ...
Nature genetics 53 (3), 342-353, 2021
1282021
Acute pharmacological degradation of Helios destabilizes regulatory T cells
NSGESF Eric S. Wang, Alyssa L. Verano, Radosław P. Nowak, J. Christine Yuan ...
Nature Chemical biology, 2021
592021
Selective degradation of GSPT1 by cereblon modulators identified via a focused combinatorial library
CE Powell, G Du, J Che, Z He, KA Donovan, H Yue, ES Wang, RP Nowak, ...
ACS chemical biology 15 (10), 2722-2730, 2020
582020
Chemo-proteomics exploration of HDAC degradability by small molecule degraders
Y Xiong, KA Donovan, NA Eleuteri, N Kirmani, H Yue, A Razov, ...
Cell chemical biology 28 (10), 1514-1527. e4, 2021
462021
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
G Du, J Jiang, NJ Henning, N Safaee, E Koide, RP Nowak, KA Donovan, ...
Cell chemical biology 29 (10), 1470-1481. e31, 2022
372022
Small-molecule approaches to targeted protein degradation
TB Faust, KA Donovan, H Yue, PP Chamberlain, ES Fischer
Annual Review of Cancer Biology 5, 181-201, 2021
332021
Structural basis of regulated m7G tRNA modification by METTL1–WDR4
J Li, L Wang, Q Hahn, RP Nowak, T Viennet, EA Orellana, ...
Nature 613 (7943), 391-397, 2023
302023
Discovery of a potent degrader for fibroblast growth factor receptor 1/2
G Du, J Jiang, Q Wu, NJ Henning, KA Donovan, H Yue, J Che, W Lu, ...
Angewandte Chemie 133 (29), 16041-16047, 2021
302021
Crystal structure of the death effector domains of caspase-8
C Shen, H Yue, J Pei, X Guo, T Wang, JM Quan
Biochemical and Biophysical Research Communications 463 (3), 297-302, 2015
292015
Structure-based design of benzo [e] isoindole-1, 3-dione derivatives as selective GSK-3β inhibitors to activate Wnt/β-catenin pathway
H Yue, F Lu, C Shen, JM Quan
Bioorganic Chemistry 61, 21-27, 2015
232015
E3-specific degrader discovery by dynamic tracing of substrate receptor abundance
A Hanzl, E Barone, S Bauer, H Yue, RP Nowak, E Hahn, EV Pankevich, ...
Journal of the American Chemical Society 145 (2), 1176-1184, 2023
162023
Attenuated response to SARS-CoV-2 vaccine in patients with asymptomatic precursor stages of Multiple Myeloma and Waldenstrom Macroglobulinemia: Results of the IMPACT Study
Y Konishi, R Sklavenitis-Pistofidis, H Yue, F Ferrari, ED Lightbody, ...
Cancer Cell 40, 6-8, 2022
162022
Enantioselective synthesis of the ABC-tricyclic core of phomactin A by a γ-hydroxylation strategy
G Du, W Bao, J Huang, S Huang, H Yue, W Yang, L Zhu, Z Liang, CS Lee
Organic letters 17 (9), 2062-2065, 2015
112015
Rapid “mix and read” assay for scalable detection of SARS-CoV-2 antibodies in patient plasma
H Yue, RP Nowak, D Overwijn, NC Payne, S Fischinger, C Atyeo, ...
medRxiv, 2020.09. 01.20184101, 2020
72020
A highly substrate-selective metal nanoreactor using a template-imprinted memory
X Liu, H Yue, S Li, W Li
Journal of Inorganic and Organometallic Polymers and Materials 19, 335-341, 2009
72009
Methods for Quantitative Assessment of Protein Degradation
RP Nowak, H Yue, EY Park, ES Fischer
Targeted Protein Degradation: Methods and Protocols, 247-263, 2021
62021
Redirecting the neo-substrate specificity of cereblon-targeting PROTACs to Helios
AL Verano, I You, KA Donovan, N Mageed, H Yue, RP Nowak, ES Fischer, ...
ACS Chemical Biology 17 (9), 2404-2410, 2022
32022
Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader
M Teng, J Jiang, ES Wang, Q Geng, ST Toenjes, KA Donovan, N Mageed, ...
Angewandte Chemie 135 (18), e202302364, 2023
22023
Expanding the HDAC druggable landscape beyond enzymatic activity
J Olivet, SG Choi, S Sierra, TM O’Grady, M de la Fuente Revenga, F Laval, ...
bioRxiv, 2022.12. 07.519454, 2022
12022
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