Variant of TREM2 Associated with the Risk of Alzheimer's Disease T Jonsson, H Stefansson, S Steinberg, I Jonsdottir, PV Jonsson, ... New England Journal of Medicine 368 (2), 107-116, 2013 | 2655 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2196 | 2019 |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2145 | 2011 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 906 | 2017 |
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 644 | 2020 |
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions VM Van Deerlin, PMA Sleiman, M Martinez-Lage, A Chen-Plotkin, ... Nature genetics 42 (3), 234-239, 2010 | 594 | 2010 |
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ... Archives of neurology 67 (12), 1473-1484, 2010 | 497 | 2010 |
Evidence for brain glucose dysregulation in Alzheimer's disease Y An, VR Varma, S Varma, R Casanova, E Dammer, O Pletnikova, ... Alzheimer's & dementia 14 (3), 318-329, 2018 | 402 | 2018 |
A multi-network approach identifies protein-specific co-expression in asymptomatic and symptomatic Alzheimer’s disease NT Seyfried, EB Dammer, V Swarup, D Nandakumar, DM Duong, L Yin, ... Cell systems 4 (1), 60-72. e4, 2017 | 398 | 2017 |
Loss of apolipoprotein E receptor LR11 in Alzheimer disease CR Scherzer, K Offe, M Gearing, HD Rees, G Fang, CJ Heilman, ... Archives of neurology 61 (8), 1200-1205, 2004 | 385 | 2004 |
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease S Steinberg, H Stefansson, T Jonsson, H Johannsdottir, A Ingason, ... Nature genetics 47 (5), 445-447, 2015 | 370 | 2015 |
Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection L Liao, D Cheng, J Wang, DM Duong, TG Losik, M Gearing, HD Rees, ... Journal of Biological Chemistry 279 (35), 37061-37068, 2004 | 353 | 2004 |
The lipoprotein receptor LR11 regulates amyloid β production and amyloid precursor protein traffic in endosomal compartments K Offe, SE Dodson, JT Shoemaker, JJ Fritz, M Gearing, AI Levey, JJ Lah Journal of Neuroscience 26 (5), 1596-1603, 2006 | 335 | 2006 |
Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease S Palmqvist, H Zetterberg, N Mattsson, P Johansson, ... Neurology 85 (14), 1240-1249, 2015 | 333 | 2015 |
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 313 | 2018 |
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease S Rangaraju, EB Dammer, SA Raza, P Rathakrishnan, H Xiao, T Gao, ... Molecular neurodegeneration 13, 1-25, 2018 | 308 | 2018 |
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, ... Proceedings of the National Academy of Sciences 110 (41), 16562-16567, 2013 | 302 | 2013 |
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly AJ Ho, JL Stein, X Hua, S Lee, DP Hibar, AD Leow, ID Dinov, AW Toga, ... Proceedings of the National Academy of Sciences 107 (18), 8404-8409, 2010 | 294 | 2010 |
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats CK Jones, AE Brady, AA Davis, Z Xiang, M Bubser, MN Tantawy, AS Kane, ... Journal of Neuroscience 28 (41), 10422-10433, 2008 | 283 | 2008 |
Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional–executive network function in Alzheimer’s disease DA Wolk, BC Dickerson, Alzheimer’s Disease Neuroimaging Initiative, ... Proceedings of the National Academy of Sciences 107 (22), 10256-10261, 2010 | 274 | 2010 |