Lukas Chavez
Lukas Chavez
Assistant Professor, Department of Medicine, University of California, San Diego (UCSD)
Verified email at - Homepage
Cited by
Cited by
DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis
F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ...
The lancet oncology 18 (5), 682-694, 2017
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
M Ko, J An, HS Bandukwala, L Chavez, T Äijö, WA Pastor, MF Segal, H Li, ...
Nature 497 (7447), 122-126, 2013
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57-62, 2016
Large conserved domains of low DNA methylation maintained by Dnmt3a
M Jeong, D Sun, M Luo, Y Huang, GA Challen, B Rodriguez, X Zhang, ...
Nature genetics 46 (1), 17-23, 2014
MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments
M Lienhard, C Grimm, M Morkel, R Herwig, L Chavez
Bioinformatics 30 (2), 284-286, 2014
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
Y Huang, L Chavez, X Chang, X Wang, WA Pastor, J Kang, ...
Proceedings of the National Academy of Sciences 111 (4), 1361-1366, 2014
PET-guided treatment in patients with advanced-stage Hodgkin's lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin …
P Borchmann, H Goergen, C Kobe, A Lohri, R Greil, DA Eichenauer, ...
The Lancet 390 (10114), 2790-2802, 2017
Innate-like functions of natural killer T cell subsets result from highly divergent gene programs
I Engel, G Seumois, L Chavez, D Samaniego-Castruita, B White, ...
Nature immunology 17 (6), 728-739, 2016
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage
L Chavez, J Jozefczuk, C Grimm, J Dietrich, B Timmermann, H Lehrach, ...
Genome research 20 (10), 1441-1450, 2010
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ...
The Lancet Oncology 19 (6), 785-798, 2018
Dynamic Changes in Chromatin Accessibility Occur in CD8+ T Cells Responding to Viral Infection
JP Scott-Browne, IF López-Moyado, S Trifari, V Wong, L Chavez, A Rao, ...
Immunity 45 (6), 1327-1340, 2016
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility
G Seumois, L Chavez, A Gerasimova, M Lienhard, N Omran, L Kalinke, ...
Nature immunology 15 (8), 777-788, 2014
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine
JP Etchegaray, L Chavez, Y Huang, KN Ross, J Choi, B Martinez-Pastor, ...
Nature cell biology 17 (5), 545-557, 2015
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ...
Nature 553 (7686), 101-105, 2018
Acute loss of TET function results in aggressive myeloid cancer in mice
J An, E González-Avalos, A Chawla, M Jeong, IF López-Moyado, W Li, ...
Nature communications 6 (1), 1-14, 2015
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome
P Panwalkar, J Clark, V Ramaswamy, D Hawes, F Yang, C Dunham, ...
Acta neuropathologica 134 (5), 705-714, 2017
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