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Paulo A. Gameiro
Paulo A. Gameiro
Principal Investigator, NOVA Medical School | Universidade Nova de Lisboa
Bestätigte E-Mail-Adresse bei nms.unl.pt
Titel
Zitiert von
Zitiert von
Jahr
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang, K Hiller, ...
Nature 481 (7381), 380-384, 2012
19142012
Oncogenic K‐Ras decouples glucose and glutamine metabolism to support cancer cell growth
D Gaglio, CM Metallo, PA Gameiro, K Hiller, LS Danna, C Balestrieri, ...
Molecular systems biology 7 (1), 523, 2011
5542011
In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation
PA Gameiro, J Yang, AM Metelo, R Pérez-Carro, R Baker, Z Wang, ...
Cell metabolism 17 (3), 372-385, 2013
3502013
Cofactor Balance by Nicotinamide Nucleotide Transhydrogenase (NNT) Coordinates Reductive Carboxylation and Glucose Catabolism in the Tricarboxylic Acid (TCA) Cycle*♦
PA Gameiro, LA Laviolette, JK Kelleher, O Iliopoulos, G Stephanopoulos
Journal of Biological Chemistry 288 (18), 12967-12977, 2013
1312013
Cytotoxic T-cells mediate exercise-induced reductions in tumor growth
H Rundqvist, P Veliça, L Barbieri, PA Gameiro, D Bargiela, M Gojkovic, ...
Elife 9, e59996, 2020
1302020
Loss of RBF1 changes glutamine catabolism
BN Nicolay, PA Gameiro, K Tschöp, M Korenjak, AM Heilmann, JM Asara, ...
Genes & development 27 (2), 182-196, 2013
962013
Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers
A Okazaki, PA Gameiro, D Christodoulou, L Laviollette, M Schneider, ...
The Journal of clinical investigation 127 (5), 1631-1645, 2017
882017
Nutrient deprivation elicits a transcriptional and translational inflammatory response coupled to decreased protein synthesis
PA Gameiro, K Struhl
Cell reports 24 (6), 1415-1424, 2018
822018
13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells
J Zhang, WS Ahn, PA Gameiro, MA Keibler, Z Zhang, G Stephanopoulos
Methods in enzymology 542, 369-389, 2014
602014
Targeted profiling of RNA translation reveals mTOR-4EBP1/2-independent translation regulation of mRNAs encoding ribosomal proteins
BB Li, C Qian, PA Gameiro, CC Liu, T Jiang, TM Roberts, K Struhl, ...
Proceedings of the National Academy of Sciences 115 (40), E9325-E9332, 2018
362018
Lactate potentiates differentiation and expansion of cytotoxic T cells
H Rundqvist, P Veliça, L Barbieri, PA Gameiro, PP Cunha, M Gojkovic, ...
BioRxiv, 571745, 2019
102019
Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells
L Barbieri, P Veliça, PA Gameiro, PP Cunha, IP Foskolou, E Rullman, ...
Frontiers in Immunology 14, 359, 2023
92023
Metabolic turnover and dynamics of modified ribonucleosides by 13C labeling
PA Gameiro, V Encheva, MS Dos Santos, JI MacRae, J Ule
Journal of Biological Chemistry 297 (5), 2021
32021
On the reprogramming of the Krebs cycle in hypoxic and VHL-deficient cancer cells
PA Gameiro
22014
Lactate regulation of activation in CD8+ T cells
L Barbieri, P Veliça, PA Gameiro, PP Cunha, IP Foskolou, D Bargiela, ...
bioRxiv, 2021.12. 14.472728, 2021
12021
Systems-level analysis of cancer metabolism
PA Gameiro, CM Metallo, G Stephanopoulos
Systems Metabolic Engineering, 349-381, 2012
12012
Cytotoxic T-cells mediate an exercise-induced reduction in tumor growth
R Johnson, H Rundqvist, P Velica, L Barbieri, P Gameiro, D Bargiela, ...
eLife Sciences Publications Ltd, 2020
2020
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