| Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2430 | 2014 |
| Pharmacogenetics: from bench to byte—an update of guidelines JJ Swen, M Nijenhuis, A de Boer, L Grandia, AH Maitland‐van der Zee, ... Clinical Pharmacology & Therapeutics 89 (5), 662-673, 2011 | 1203 | 2011 |
| Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions A Vermes, HJ Guchelaar, J Dankert Journal of Antimicrobial Chemotherapy 46 (2), 171-179, 2000 | 894 | 2000 |
| The risk of cancer in users of statins MR Graaf, AB Beiderbeck, ACG Egberts, DJ Richel, HJ Guchelaar Journal of clinical oncology 22 (12), 2388-2394, 2004 | 619 | 2004 |
| Cardiotoxicity of cytotoxic drugs KJM Schimmel, DJ Richel, RBA Van den Brink, HJ Guchelaar Cancer treatment reviews 30 (2), 181-191, 2004 | 550 | 2004 |
| Clinical pharmacokinetics of tyrosine kinase inhibitors NP van Erp, H Gelderblom, HJ Guchelaar Cancer treatment reviews 35 (8), 692-706, 2009 | 470 | 2009 |
| Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and … KE Caudle, K Sangkuhl, M Whirl‐Carrillo, JJ Swen, CE Haidar, TE Klein, ... Clinical and translational science 13 (1), 116-124, 2020 | 425 | 2020 |
| Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis JAM Wessels, TWJ Huizinga, HJ Guchelaar Rheumatology 47 (3), 249-255, 2008 | 425 | 2008 |
| Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer MR Graaf, DJ Richel, CJF van Noorden, HJ Guchelaar Cancer treatment reviews 30 (7), 609-641, 2004 | 367 | 2004 |
| DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis LM Henricks, CATC Lunenburg, FM de Man, D Meulendijks, ... The Lancet Oncology 19 (11), 1459-1467, 2018 | 331 | 2018 |
| Making sense of big data in health research: towards an EU action plan C Auffray, R Balling, I Barroso, L Bencze, M Benson, J Bergeron, ... Genome medicine 8, 1-13, 2016 | 326 | 2016 |
| Liposomal drug formulations in cancer therapy: 15 years along the road M Slingerland, HJ Guchelaar, H Gelderblom Drug discovery today 17 (3-4), 160-166, 2012 | 316 | 2012 |
| A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent‐onset rheumatoid arthritis JAM Wessels, SM van der Kooij, S le Cessie, W Kievit, P Barerra, ... Arthritis & Rheumatism 56 (6), 1765-1775, 2007 | 298 | 2007 |
| Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single‐nucleotide polymorphisms in genes coding for folate pathway enzymes JAM Wessels, JK de Vries‐Bouwstra, BT Heijmans, PE Slagboom, ... Arthritis & Rheumatism 54 (4), 1087-1095, 2006 | 296 | 2006 |
| Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy MP Goetz, K Sangkuhl, HJ Guchelaar, M Schwab, M Province, ... Clinical Pharmacology & Therapeutics 103 (5), 770-777, 2018 | 295 | 2018 |
| Pharmacogenetics: from bench to byte JJ Swen, I Wilting, AL De Goede, L Grandia, H Mulder, DJ Touw, ... Clinical pharmacology & therapeutics 83 (5), 781-787, 2008 | 292 | 2008 |
| Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium CH van der Wouden, A Cambon‐Thomsen, E Cecchin, KC Cheung, ... Clinical Pharmacology & Therapeutics 101 (3), 341-358, 2017 | 289 | 2017 |
| Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment HJ Guchelaar, A Vermes, JH Meerwaldt Supportive care in cancer 5, 281-288, 1997 | 251 | 1997 |
| Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer MJ Deenen, J Tol, AM Burylo, VD Doodeman, A De Boer, A Vincent, ... Clinical Cancer Research 17 (10), 3455-3468, 2011 | 247 | 2011 |
| Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity NP van Erp, K Eechoute, AA van der Veldt, JB Haanen, AKL Reyners, ... Journal of Clinical Oncology 27 (26), 4406-4412, 2009 | 237 | 2009 |
Hans GelderblomLUMCVerified email at lumc.nl
