Optimization of an in silico cardiac cell model for proarrhythmia risk assessment S Dutta, KC Chang, KA Beattie, J Sheng, PN Tran, WW Wu, M Wu, ... Frontiers in Physiology 8, 616, 2017 | 191 | 2017 |
Uncertainty quantification reveals the importance of data variability and experimental design considerations for in silico proarrhythmia risk assessment KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ... Frontiers in physiology 8, 917, 2017 | 91 | 2017 |
Evaluation of an in silico cardiac safety assay: using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge KA Beattie, C Luscombe, G Williams, J Munoz-Muriedas, DJ Gavaghan, ... Journal of pharmacological and toxicological methods 68 (1), 88-96, 2013 | 73 | 2013 |
Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics KA Beattie, AP Hill, R Bardenet, Y Cui, JI Vandenberg, DJ Gavaghan, ... The Journal of physiology 596 (10), 1813-1828, 2018 | 71 | 2018 |
Four ways to fit an ion channel model M Clerx, KA Beattie, DJ Gavaghan, GR Mirams Biophysical Journal 117 (12), 2420-2437, 2019 | 59 | 2019 |
Considering discrepancy when calibrating a mechanistic electrophysiology model CL Lei, S Ghosh, DG Whittaker, Y Aboelkassem, KA Beattie, CD Cantwell, ... Philosophical Transactions of the Royal Society A 378 (2173), 20190349, 2020 | 58 | 2020 |
Rapid characterization of hERG channel kinetics II: temperature dependence CL Lei, M Clerx, KA Beattie, D Melgari, JC Hancox, DJ Gavaghan, ... Biophysical Journal 117 (12), 2455-2470, 2019 | 48 | 2019 |
Reproducible model development in the cardiac electrophysiology Web Lab AC Daly, M Clerx, KA Beattie, J Cooper, DJ Gavaghan, GR Mirams Progress in biophysics and molecular biology 139, 3-14, 2018 | 26 | 2018 |
Ten simple rules for surviving an interdisciplinary PhD S Demharter, N Pearce, K Beattie, I Frost, J Leem, A Martin, ... PLOS Computational Biology 13 (5), e1005512, 2017 | 11 | 2017 |
Corrigendum: Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment S Dutta, KC Chang, KA Beattie, J Sheng, PN Tran, WW Wu, M Wu, ... Frontiers in physiology 8, 1025, 2017 | 6 | 2017 |
Mathematical modelling of drug-ion channel interactions for cardiac safety assessment KA Beattie University of Oxford, 2015 | 5 | 2015 |
Voltage protocol design for determining hERG channel kinetics K Beattie, T de Boer, D Gavaghan, J Louttit, G Mirams Journal of Pharmacological and Toxicological Methods, 164, 2015 | 3 | 2015 |
Mathematical modelling of hERG channel kinetics using sinusoidal voltage protocols KA Beattie, R Bardenet, JB Louttit, JI Vandenberg, AP Hill, DJ Gavaghan, ... Elsevier 88 (2), 2017 | 2 | 2017 |
Novel voltage protocols for determining hERG channel kinetics GR Mirams, K Beattie, JB Louttit, T de Boer, DJ Gavaghan Biophysical Journal 108 (2), 121a, 2015 | 2 | 2015 |
Exploring temperature-dependence of hERG channel kinetics using sine wave voltage protocols K Beattie, D Melgari, J Hancox, G Mirams Journal of Pharmacological and Toxicological Methods 100 (81), 339-340, 2016 | | 2016 |
6 Can you teach an old dog new tricks? The anti-malarial hydroxychloroquine shows promise in cardiac rate control through actions at the sino-atrial node RA Capel, GR Mirams, KA Beattie, DJ Paterson, DA Terrar, RAB Burton Heart 101 (Suppl 6), A2-A2, 2015 | | 2015 |
Department of Computer Science Student Conference 2014 A Potter, J Buys, S Gogioso, A Hadzishanovic, A Jones, K Beattie, L Chen | | 2014 |
Supplementary material for: Evaluation of an In-Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge KA Beattie, C Luscombe, G Williams, J Munoz-Muriedas, DJ Gavaghan, ... | | 2013 |
Evaluation of computational modelling as a preclinical proarrhythmic safety assay K Beattie, D Gavaghan, G Mirams, G Williams Journal of Pharamcological and Toxicological Methods 86, 2013 | | 2013 |
Evaluation of computational modelling as a preclinical proarrhythmic safety assay G Mirams, K Beattie, Y Cui, C Luscombe, G Williams, D Gavaghan, ... In-vitro Toxicology, 2012 | | 2012 |