| The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity B Viollet, F Andreelli, SB Jørgensen, C Perrin, A Geloen, D Flamez, J Mu, ... The Journal of clinical investigation 111 (1), 91-98, 2003 | 631 | 2003 |
| Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis D Scheuner, DV Mierde, B Song, D Flamez, JWM Creemers, K Tsukamoto, ... Nature medicine 11 (7), 757-764, 2005 | 473 | 2005 |
| Selective inhibition of eukaryotic translation initiation factor 2α dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic β-cell … M Cnop, L Ladriere, P Hekerman, F Ortis, AK Cardozo, Z Dogusan, ... Journal of Biological Chemistry 282 (6), 3989-3997, 2007 | 362 | 2007 |
| Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells K Moens, H Heimberg, D Flamez, P Huypens, E Quartier, Z Ling, ... Diabetes 45 (2), 257-261, 1996 | 333 | 1996 |
| Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models B Viollet, F Andreelli, SB Jørgensen, C Perrin, D Flamez, J Mu, ... Biochemical Society Transactions 31 (1), 216-219, 2003 | 287 | 2003 |
| A globin in the nucleus! E Geuens, I Brouns, D Flamez, S Dewilde, JP Timmermans, L Moens Journal of Biological Chemistry 278 (33), 30417-30420, 2003 | 218 | 2003 |
| Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor-/-mice. RA Pederson, M Satkunarajah, CH McIntosh, LA Scrocchi, D Flamez, ... Diabetes 47 (7), 1046-1052, 1998 | 202 | 1998 |
| Cytokines interleukin-1β and tumor necrosis factor-α regulate different transcriptional and alternative splicing networks in primary β-cells F Ortis, N Naamane, D Flamez, L Ladriere, F Moore, DA Cunha, ML Colli, ... Diabetes 59 (2), 358-374, 2010 | 190 | 2010 |
| Detailed transcriptome atlas of the pancreatic beta cell B Kutlu, D Burdick, D Baxter, J Rasschaert, D Flamez, DL Eizirik, N Welsh, ... BMC medical genomics 2, 1-11, 2009 | 157 | 2009 |
| Glucose-regulated gene expression maintaining the glucose-responsive state of β-cells F Schuit, D Flamez, A De Vos, D Pipeleers Diabetes 51 (suppl_3), S326-S332, 2002 | 139 | 2002 |
| Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1 D Delmeire, D Flamez, SA Hinke, JJ Cali, D Pipeleers, F Schuit Diabetologia 46, 1383-1393, 2003 | 138 | 2003 |
| Double-stranded RNA induces pancreatic β-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways Z Dogusan, M Garcia, D Flamez, L Alexopoulou, M Goldman, ... Diabetes 57 (5), 1236-1245, 2008 | 132 | 2008 |
| Disruption of the γ-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of β-cells CA Gysemans, L Ladriere, H Callewaert, J Rasschaert, D Flamez, ... Diabetes 54 (8), 2396-2403, 2005 | 128 | 2005 |
| Critical role for cataplerosis via citrate in glucose-regulated insulin release D Flamez, V Berger, M Kruhøffer, T Orntoft, D Pipeleers, FC Schuit Diabetes 51 (7), 2018-2024, 2002 | 126 | 2002 |
| Dual glucagon recognition by pancreatic β-cells via glucagon and glucagon-like peptide 1 receptors K Moens, D Flamez, CV Schravendijk, Z Ling, D Pipeleers, F Schuit Diabetes 47 (1), 66-72, 1998 | 122 | 1998 |
| Glucagon-like peptide 1 receptor signaling influences topography of islet cells in mice Z Ling, D Wu, Y Zambre, D Flamez, DJ Drucker, DG Pipeleers, FC Schuit Virchows Archiv 438, 382-387, 2001 | 115 | 2001 |
| Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas I Rooman, J Lardon, D Flamez, F Schuit, L Bouwens Gastroenterology 121 (4), 940-949, 2001 | 106 | 2001 |
| T1DBase: integration and presentation of complex data for type 1 diabetes research EM Hulbert, LJ Smink, EC Adlem, JE Allen, DB Burdick, OS Burren, ... Nucleic acids research 35 (suppl_1), D742-D746, 2007 | 94 | 2007 |
| Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate E Louagie, NA Taylor, D Flamez, AJM Roebroek, NA Bright, S Meulemans, ... Proceedings of the National Academy of Sciences 105 (34), 12319-12324, 2008 | 91 | 2008 |
| Altered cAMP and Ca2+ signaling in mouse pancreatic islets with glucagon-like peptide-1 receptor null phenotype. D Flamez, P Gilon, K Moens, A Van Breusegem, D Delmeire, LA Scrocchi, ... Diabetes 48 (10), 1979-1986, 1999 | 91 | 1999 |
