Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13535* | 2021 |
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition S Doll, B Proneth, YY Tyurina, E Panzilius, S Kobayashi, I Ingold, M Irmler, ... Nature chemical biology 13 (1), 91-98, 2017 | 2823 | 2017 |
Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1939 | 2013 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1019 | 2021 |
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ... Nature 541 (7635), 81-86, 2017 | 908 | 2017 |
Novel biomarkers for pre‐diabetes identified by metabolomics R Wang‐Sattler, Z Yu, C Herder, AC Messias, A Floegel, Y He, K Heim, ... Molecular systems biology 8 (1), 615, 2012 | 794 | 2012 |
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations M Kolz, T Johnson, S Sanna, A Teumer, V Vitart, M Perola, M Mangino, ... PLoS genetics 5 (6), e1000504, 2009 | 781 | 2009 |
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ... Nature communications 9 (1), 2941, 2018 | 774 | 2018 |
Systematic screen for human disease genes in yeast LM Steinmetz, C Scharfe, AM Deutschbauer, D Mokranjac, ZS Herman, ... Nature genetics 31 (4), 400-404, 2002 | 666 | 2002 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 652 | 2019 |
The transcriptional landscape of age in human peripheral blood MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ... Nature communications 6 (1), 1-14, 2015 | 642 | 2015 |
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium N Soranzo, TD Spector, M Mangino, B Kühnel, A Rendon, A Teumer, ... Nature genetics 41 (11), 1182-1190, 2009 | 622 | 2009 |
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity CJ Gloeckner, N Kinkl, A Schumacher, RJ Braun, E O'Neill, T Meitinger, ... Human molecular genetics 15 (2), 223-232, 2006 | 580 | 2006 |
Differences between human plasma and serum metabolite profiles Z Yu, G Kastenmüller, Y He, P Belcredi, G Möller, C Prehn, J Mendes, ... PloS one 6 (7), e21230, 2011 | 574 | 2011 |
Genetic diagnosis of Mendelian disorders via RNA sequencing LS Kremer, DM Bader, C Mertes, R Kopajtich, G Pichler, A Iuso, TB Haack, ... Nature communications 8 (1), 15824, 2017 | 548 | 2017 |
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects A Döring, C Gieger, D Mehta, H Gohlke, H Prokisch, S Coassin, G Fischer, ... Nature genetics 40 (4), 430-436, 2008 | 526 | 2008 |
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 509 | 2018 |
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study JC Chambers, M Loh, B Lehne, A Drong, J Kriebel, V Motta, S Wahl, ... The lancet Diabetes & endocrinology 3 (7), 526-534, 2015 | 485 | 2015 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 462 | 2010 |
Phenotypic spectrum associated with mutations of the mitochondrial polymerase γ gene R Horvath, G Hudson, G Ferrari, N Fütterer, S Ahola, E Lamantea, ... Brain 129 (7), 1674-1684, 2006 | 458 | 2006 |